Hello Caroline.
Thank you for your question.
Firstly, answers and comments provided on Google Answers are general
information, and are not intended to be a substitute for informed
professional medical, or other professional advice.
When calculating the dosage for Augmentin suspension for pediatric
patients, it is based on the amoxicillin component according to the
information provided in this detailed publication about Augmentin
Powder for Oral Suspension and Chewable Tablets by GlaxoSmithKline
published in May 2002.
Source: GlaxoSmithKline Website
http://us.gsk.com/products/assets/us_augmentin_powder.pdf
AUGMENTIN
amoxicillin/clavulanate potassium
Powder for Oral Suspension and Chewable Tablets
Page 11
-------------------------
DOSAGE AND ADMINISTRATION
-------------------------
Dosage:
Pediatric Patients:
*** Based on the amoxicillin component, Augmentin should be dosed as
follows:
Neonates and infants aged < 12 weeks (3 months):
“Due to incompletely developed renal function affecting elimination of
amoxicillin in this age group, the recommended dose of Augmentin is 30
mg/kg/day divided q12h, based on the amoxicillin component.
Clavulanate elimination is unaltered in this age group. Experience
with the 200 mg/5 mL formulation in this age group is limited and,
thus, use of the 125 mg/5 mL oral suspension is recommended.”
There is a chart for the dosage for patients aged 12 weeks (3 months)
and older on page 12 of this publication.
Each strength of Augmentin suspension is available as a chewable
tablet for use by older children.
Page 12
Pediatric patients weighing 40 kg and more should be dosed according
to the following adult recommendations:
“The usual adult dose is 1 Augmentin 500 mg tablet every 12 hours or 1
Augmentin 250 mg tablet every 8 hours. For more severe infections and
infections of the respiratory tract, the dose should be 1 Augmentin
875 mg tablet every 12 hours or 1 Augmentin 500 mg tablet every 8
hours. Among adults treated with 875 mg every 12 hours, significantly
fewer experienced severe diarrhea or withdrawals with diarrhea vs.
adults treated with 500 mg every 8 hours.”
“The Augmentin 250 mg tablet and the 250 mg chewable tablet do not
contain the same amount of clavulanic acid (as the potassium salt).
The Augmentin 250 mg tablet contains 125 mg of clavulanic acid,
whereas the 250 mg chewable tablet contains 62.5 mg of clavulanic
acid. Therefore, the Augmentin 250 mg tablet and the 250 mg chewable
tablet should not be substituted for each other, as they are not
interchangeable.”
NOTE:
“Due to the different amoxicillin to clavulanic acid ratios in the
Augmentin 250 mg tablet (250/125) versus the Augmentin 250 mg chewable
tablet (250/62.5), the Augmentin 250 mg tablet should not be used
until the child weighs at least 40 kg and more.”
Page 13
Administration:
Augmentin may be taken without regard to meals; however, absorption of
clavulanate potassium is enhanced when Augmentin is administered at
the start of a meal. To minimize the potential for gastrointestinal
intolerance, Augmentin should be taken at the start of a meal.
How Supplied:
AUGMENTIN 125 MG/5 ML FOR ORAL SUSPENSION: Each 5 mL of reconstituted
banana-flavored suspension contains 125 mg amoxicillin and 31.25 mg
clavulanic acid as the potassium salt.
NDC 0029-6085-39....................75 mL bottle
NDC 0029-6085-22...................150 mL bottle
NDC 0029-6085-23...................100 mL bottle
Source: GlaxoSmithKline Website
http://us.gsk.com/products/assets/us_augmentin_powder.pdf
Augmentin Website
http://www.augmentin.com/
Search Criteria:
dosage for Augmentin suspension for a child,
I hope you find this helpful, and I must emphasize that answers given
here are for general information, and are not intended to be a
substitute for informed medical advice.
Best Regards,
Bobbie7-ga |
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