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Q: In Vivo Models Of Cancer Research ( Answered,   0 Comments )
Question  
Subject: In Vivo Models Of Cancer Research
Category: Science > Biology
Asked by: greatone100-ga
List Price: $2.00
Posted: 26 Nov 2002 14:13 PST
Expires: 26 Dec 2002 14:13 PST
Question ID: 115064
Typical means used to evaluate the effects of a drug in animal models
of cancer include which of the following? (there may be more than one)
a. measurement of % inhibition of tumor growth
b. measurement of time of delay for the tumore to grow to a certain
size
c. measurement of the weight changes of the lungs in experimental lung
metastatic tumor models
d. measurement of time to death
Answer  
Subject: Re: In Vivo Models Of Cancer Research
Answered By: synarchy-ga on 03 Dec 2002 03:14 PST
 
Hi -

These are all measured endpoints in various studies.

Answers a,b are similar methods for estimating the effect upon growth
- answer b is an example of a threshold type measurement.  A company
which offers services such as these:
http://www.artp.org/pros-tum/BAS_pt27e.htm

A description of cancer research including studies which use "time to
death"
http://www.rxlist.com/cgi/generic2/nilutam_cp.htm

An abstract describing a study using lung weight to measure tumor
growth:
http://www.oncolyticsbiotech.com/022801p1.html

search:
Google: drug tumor animal model "tumor growth"
Google: tumor animal model "time to death"
Google: tumor animal model "lung weight"
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