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Q: age probability distribution for pancreatic cancer death ( Answered,   1 Comment )
Question  
Subject: age probability distribution for pancreatic cancer death
Category: Health > Conditions and Diseases
Asked by: whitney-ga
List Price: $10.00
Posted: 16 Jan 2003 02:00 PST
Expires: 15 Feb 2003 02:00 PST
Question ID: 144120
what percentage of deaths caused by pancreatic cancer occur at age 32
or younger?  for an additional $10, same question but instead of
drawing from all who died of pancreatic cancer, just draw from smokers
dying of pancreatic cancer.

Request for Question Clarification by answerfinder-ga on 16 Jan 2003 04:30 PST
I have found statistics for percentage of deaths but the age group is
34 and younger. Is this acceptable? I have been unable to find
comparable data for smokers. However the site contains extensive
information on other pancreatic cancer statistics.
answerfinder-ga

Clarification of Question by whitney-ga on 16 Jan 2003 15:10 PST
that's okay.
Answer  
Subject: Re: age probability distribution for pancreatic cancer death
Answered By: tar_heel_v-ga on 16 Jan 2003 16:35 PST
 
whitney..

Thank you for your quesion.  According to the National Cancer
Institute:
"Pancreatic cancer is rare in the 30-54 years age group. In the 55-69
years age group, incidence rates in the black populations exceed those
for whites by about 60%. This difference diminishes somewhat among
persons aged 70 years and older. Incidence rates for Japanese men and
women exceed those for the white population in the oldest age group.
Racial/ethnic patterns in mortality rates by age group closely follow
those seen in the incidence rates.

Cigarette smoking has been identified consistently as an important
risk factor for cancer of the pancreas. Other risk factors which have
been suggested, but not confirmed include coffee drinking, high fat
diets, diabetes mellitus and some occupations."

Below are statistics that give the mortality rate based upon age:

Age   Death Rate per 100,000 Cases
00-04             0.0042 
05-09             0.0020 
10-14             0.0010
15-19             0.0063
20-24             0.0327
25-29             0.0631
30-34             0.2166
Source:
National Cancer Institute
U.S. Mortality Crude Rates, Total U.S., 1969-1999
http://canques.seer.cancer.gov/cgi-bin/cq_submit?dir=seer1999&db=9&rpt=LINE&sel=1^26^1^^0^&x=Age%20at%20death^1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18&y=Race^0,1,2&dec=4

Regarding the rate among smokers, I didn't find specific data, however
I did find the following data:
----
Study finds smoking triggers earlier pancreatic cancer
"A study of almost 500 people with hereditary pancreatitis found that
smokers developed pancreatic cancer about 20 years earlier than
nonsmokers did"
http://www.post-gazette.com/healthscience/20010711cancer0711p2.asp
----
"Pancreatic cancer in smoking males is increased by 41%
Pancreatic cancer in smoking females is increased by 19%"
MORTALITY AND MORBIDITY RATES ASSOCIATED WITH TOBACCO USE
http://members.aol.com/NurseVH/smoking2.html
----
Cigarette smoking and pancreas cancer: A case-control study of the
search programme of the IARC
"Risk of pancreas cancer was found to increase with increasing
lifetime consumption of cigarettes, the relative risk rising to 2.70
(95% C.I. 1.95 to 3.74) in the highest intake category"
International Journal of Cancer Volume 67, Issue 1, 1996. Pages: 63-71
http://www3.interscience.wiley.com/cgi-bin/abstract/59964/START
----
"In 1985, pancreatic cancer deaths attributable to smoking were 29_
for men & 34_ for women"
Indiana Tobacco Control Center
http://iumeded.med.iupui.edu/tobacco/smoker-chewer/male_chart.html
----
"Cigarette smoking is at least a contributory and may be a causal
factor in the development of pancreatic cancer. It is estimated that
24% of pancreatic cancer in males and 19% in females is attributable
to smoking"
Other cancers caused by or associated with smoking
http://www.quit.org.au/quit/FandI/fandi/c03s4.htm
----

Thanks again for your question. If you need any additional
clarification, please let me know.  You can get extremely granular
data at The National Cancer Institute Surveillance, Epidemiology, and
End Results (S.E.E.R.) Website:

Incidences of Pancreatic Cancer
http://seer.cancer.gov/faststats/html/inc_pancreas.html

Mortality of Pancreatic Cancer
http://seer.cancer.gov/faststats/html/mor_pancreas.html

Prevelance of Pancreatic Cancer
http://seer.cancer.gov/faststats/html/pre_pancreas.html

Regards,

-THV

Search Strategy:
Pancreatic Cancer mortality rates
Pancreatic Cancer mortality rates smokers

Request for Answer Clarification by whitney-ga on 16 Jan 2003 22:39 PST
could you specifically answer the question as in "xx% of pancreatic
cancer deaths occur at age 34 and below" and show me what data you
used to arrive at that.  thanks!

Clarification of Answer by tar_heel_v-ga on 17 Jan 2003 09:02 PST
In 1998, there were 28,335 deaths in the United States attributed to
pancreatic cancer.  Of that number, 150 were in individuals aged 34
and under.  This equals out to less than 1% of all the deaths caused
be pancreatic cancer occuring in individuals 34 years old or younger. 
You can see the specific breakdown by 5 year age groups at
http://www.cdc.gov/nchs/data/mortab/98gm3_02.pdf.  You will need Adobe
Acrobat Reader to view this file.

I hope this clarification answers your questions.  If you need
additional information, please let me know.

Regards,

-THV

Source:
National Center for Health Statistics Mortality Tables, GMIII_2_98
http://www.cdc.gov/nchs/data/mortab/98gm3_02.pdf
Comments  
Subject: Re: age probability distribution for pancreatic cancer death
From: answerfinder-ga on 17 Jan 2003 09:05 PST
 
From the pdf file http://seer.cancer.gov/csr/1973_1999/overview/overview15.pdf
the following appears:
Table I-13
AGE DISTRIBUTION (%) OF DEATHS BY SITE, 1995-99
All Races, Both Sexes
Pancreas
Ages 0 – 34   0.2% of a total of 139,112 deaths.
answerfinder-ga

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