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Q: harsh chemicals ( Answered 5 out of 5 stars,   3 Comments )
Question  
Subject: harsh chemicals
Category: Science > Chemistry
Asked by: anonymous777-ga
List Price: $50.00
Posted: 22 Jan 2003 15:06 PST
Expires: 21 Feb 2003 15:06 PST
Question ID: 147187
i need the exact order of these chemicals from most to least harsh on
ur skin/
ammonium lauryl sulfate,ammonium laureth sulfate, sodium lauryl
sulfate, and sodium laureth sulfate. i have read many contridicting
reports on the web and i cant find one exact ansewr. all of these are
found in shampoos and i need documentation or 100% proof what is the
harshest chemicals in order. i find many people saying that ammoniums
are worse then the soduims, and then i find that ammonum laurth is
better then sodium laurth, and then i find that sodium laurth is the
best and soduim lauryl is the worst???? what is what!!! can u find a
100% answer?? call a chemist if need be. thanks for ur help!
Answer  
Subject: Re: harsh chemicals
Answered By: tutuzdad-ga on 22 Jan 2003 20:10 PST
Rated:5 out of 5 stars
 
Dear anonymous777-ga;

Thank you for allowing me an opportunity to answer your interesting
question.

In order to answer your question, I direct you to this document
wherein an independent organization called the Cosmetic Ingredient
Review (CIR) (an independent panel comprised of a seven expert members
in the fields of dermatology, pharmacology, chemistry, and toxicology)
reported their findings regarding the safety of these substances:

Taken from: SLS ALERT
http://www.healthy-communications.com/slsalert.html

The report says in part:

“Sodium Laureth Sulfate and Ammonium Laureth Sulfate are cosmetic
detergents that exert emulsifying action…these two ingredients produce
eye and/or skin irritation in experimental animals and in some human
test subjects; irritation may occur in some users of cosmetic
formulations containing the ingredients under consideration. The
irritant effects are similar to those produced by other detergents,
and the severity of the irritation appears to increase directly with
concentration. However, Sodium and Ammonium Laureth Sulfate have not
evoked adverse responses in any other toxicologic testing.”

“It is recognized that Sodium and Ammonium Laureth Sulfate may induce
eye and skin irritation. However, on the basis of the available
information, the Panel concludes that Sodium Laureth Sulfate and
Ammonium Laureth Sulfate are  not as safe as presently used in
cosmetic products in amounts over 2%.. Most consumer products contain
more than 20% of sls.”

These finding were published in the “Journal of the American College
of Toxicology”, Volume 2, Number 5, pp. 1-34, 1983.

The Review goes on to say, in part:

“Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate are irritants in
patch testing at concentrations of 2 percent and greater, and that
irritation increases with ingredient concentration…”

“The longer these ingredients stay in contact with the skin, the
greater the likelihood of irritation…”

“Although Sodium Lauryl Sulfate is not carcinogenic in experimental
animals, it has been shown that it causes severe epidermal changes to
the area of the skin of mice to which it was applied.”

“…studies of rat skin treated with radiolabelled Sodium Lauryl Sulfate
found heavy deposition of the detergent on the skin surface and in the
hair follicles; damage to the hair follicle could result from such
deposition.”

“Further, it has been reported that 1 percent and 5 percent Sodium
Lauryl Sulfate produced significant number of comedones when applied
to the pinna of albino rabbits. These two problems - possible hair
loss and comedone formation - along with proven irritancy…”

“Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate appear to pose less
potential hazard when in products designed for brief, discontinuous
use, following which they are thoroughly rinsed from the surface of
the skin. However, consumers who use these products daily and are
exposed at much higher rates, thus increasing the cumulative effect of
using these chemicals.”

“…the reports also are in agreement that this is a chemical that
should be reduced, reformulated or taken out of the products in public
consumption products.”

These findings were also published in the “Journal of the American
College of Toxicology”, Volume 2, Number 7, pp. 127-181, 1983.

Clearly then, if your term “harsh” refers to potential irritation and
damage to the skin and the hair follicle, both Sodium Laureth Sulfate
and Ammonium Laureth Sulfate have been found to pose roughly the same
potential threat as the other in terms of “harshness”, while neither
has been found to be nearly as harsh as either Sodium Lauryl Sulfate
or Ammonium Lauryl Sulfate, which again are relatively equal in terms
of “harshness”. Regardless of what you may have read, heard or been
told by labels, manufacturers or retailers, this information, in the
form of a formal, independent toxicology report has been published by
one of the most eminent toxicology journals in existence.

Below you will find that I have carefully defined my search strategy
for you in the event that you need to search for more information. By
following the same type of searches that I did you may be able to
enhance the research I have provided even further. I hope you find
that that my research exceeds your expectations. If you have any
questions about my research please post a clarification request prior
to rating the answer. Otherwise, I welcome your rating and your final
comments and I look forward to working with you again in the near
future. Thank you for bringing your question to us.

Best regards;
Tutuzdad-ga


INFORMATION SOURCES

HEALTHY COMMUNICATIONS - SLS ALERT
http://www.healthy-communications.com/slsalert.html


JOURNAL OF AMERICAN COLLEGE OF TOXICOLOGY
http://www.aromaleigh.com/finreponsafa.html


SEARCH STRATEGY


SEARCH ENGINE USED:

Google ://www.google.com


SEARCH TERMS USED:


“Sodium Laureth Sulfate”

“Ammonium Laureth Sulfate”

“Sodium Laureth Sulfate”

“Ammonium Laureth Sulfate”

Toxicology “Sodium Laureth Sulfate”

Toxicology “Ammonium Laureth Sulfate”

Toxicology “Sodium Laureth Sulfate”

Toxicology “Ammonium Laureth Sulfate”

Hazards “Sodium Laureth Sulfate”

Hazards “Ammonium Laureth Sulfate”

Hazards “Sodium Laureth Sulfate”

Hazards “Ammonium Laureth Sulfate”

Request for Answer Clarification by anonymous777-ga on 22 Jan 2003 20:45 PST
the info is great but i need u to put them in a order for me. in all
the research u found what is the order of harshness on the skin from 1
to 4. 1 being the most harh and 4 being the least. thank u

Request for Answer Clarification by anonymous777-ga on 22 Jan 2003 20:47 PST
my only concern for these chemicals are in my shampoos

Clarification of Answer by tutuzdad-ga on 23 Jan 2003 06:40 PST
Dear anonymous777-ga;

Again, according to the “Journal of the American College of
Toxicology" two of these chemical components are virtually alike in
terms of harshness while the second two are almost like the other as
well.

Based on the information I read on the second source I provided for
you, if I had to list them in single order, 1 (being least harsh) to
(4 being most harsh) the list would look like this:

1. Sodium Laureth Sulfate
2. Ammonium Laureth Sulfate 
3. Sodium Lauryl Sulfate
4. Ammonium Lauryl Sulfate 

I tend to agree also with the statement by "tehuti-ga" below. It seems
that as "lauryl" is transformed into "laureth" it also looses some of
it irritating properties. This places the "laureths" higher on the
desirability scale than the "lauryls". While sodium (in this case)
refers to a mild surfactant, ammonium is (in this case) little more
than an acid detergent. So you see, what ultimately determines how
tempered these chemical are is how much of the sodium or ammonium is
actually used (percentage, ratio, parts per, or whatever)and whether
or not it has been married up with a lauryl or laureth.

Just to recap, I derived my information from a widely respected
journal. I too have seen some claims to the contrary but almost all of
the sites I saw were sites that were either old (prior to the studies
I offered) or they are owned and operated by a biased retailer or
manufacturer whose claims and motives I tend to question.

Regards;
tutuzsdad-ga
anonymous777-ga rated this answer:5 out of 5 stars

Comments  
Subject: Re: harsh chemicals
From: bobbie7-ga on 22 Jan 2003 20:57 PST
 
Hello anonymous777-ga,

I found this article that may interest you.

Look at the label!!! Here is a guide to how gentle your shampoo is
according to the surfactant used:

Ammonium Lauryl Sulfate - very, very, harsh

Ammonium Laureth Sulfate- very harsh but better than the above

Sodium Lauryl Sulfate- better than the above, but still a little harsh

Sodium Laureth Sulfate-gentle, great pick!

TEA lauryl Sulfate-good pick

TEA Laureth Sulfate-good pick
http://www.geocities.com/HotSprings/4266/shampoo.html

I hope this helps.

--Bobbie7-ga (Researcher)
Subject: Re: harsh chemicals
From: anonymous777-ga on 22 Jan 2003 21:28 PST
 
thanks but my problem is that i have found other sites put those same
chemicals in a differeny order.
Subject: Re: harsh chemicals
From: tehuti-ga on 23 Jan 2003 02:35 PST
 
The ethoxylation of the "lauryl" forms into the "laureth" forms
reduces irritancy to a certain extent. To get an estimate of relative
harshness, you need to have comparative objective data for the
chemicals tested simultaneously at the same concentrations in the same
system, eg Draize scores.  I did spend time on this question last
night, however, while I found data giving Draize scores for sodium
lauryl vs. sodium laureth sulfate, and "primary irritation scores"
(which given that the citation I found was from a 1967 paper, I
presume to refer to Draize scores) for sodium lauryl vs. ammonium
lauryl sulfate, I was unable to get similar data for sodium laureth
vs. ammonium laureth sulfate, ammonium laureth vs ammonium lauryl
sulfate and ammonium laureth vs. sodium lauryl sulfate, and therefore
felt myself unable to give you the answer you were seeking, namely the
ranking order of all four compounds.

All four chemicals are anionic surfactants, which as a class are
harsher than other types of surfactants.  Thus, manufacturers of some
baby shampoos exclude all anionic surfactants, and confine themselves
to using only amphoteric surfactants instead.

However, there is a further complication.  The irritancy of
surfactants has been found to correlate with their critical micellar
concentration: the higher the CMC, the greater the irritancy. It is
possible to reduce the CMC by the addition of other compounds.  This
is part of the art and science of cosmetic formulation. Also,
irritancy is strongly dependent on the concentration of the surfactant
used in a product.

For these reasons, it is not really possible to say that Product A is
worse than Product B simply because it contains one anionic surfactant
compared to another. You need to know the overall irritancy score of
the formulation.  That is why the testing of cosmetics and toiletries
involves not just the testing of individual ingredients, but also the
testing of the finished product.  However, this data is unlikely to be
available, except to the manufacturer.  A laboratory I know, which is
involved in the development of non-animal tests for cosmetics, has in
the past tested finished formulations in their systems for some
manufacturers, and had to sign confidentiality agreements not to
release this data to anyone else. Even if this data were available, it
would be difficult to make an absolute comparison between two
products, except if they had been tested in the same laboratory at the
same time, because the test systems used do have a certain level of
inherent variability.  Furthermore, some of the test systems used do
not produce absolute values as such, but simply permit the test
substance to be classed as non-irritant, mildly irritant, moderately
irritant or severely irritant.

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