Please help me to answer the following question. Questions 1 through
14, for each statement, mark T for true.
example . Insulin: a,b,d true
a. is a polypeptide T
b. for human use is extracted from pig pancreas T
c. is administered orally
d. acts by enhancing cellular uptake of glucose T
e. acts by enhancing cellular utilization of glucose
1. Relaxation of the uterus may be induced by
a. progesterone
b. salbutamol
c. ethanol
d. prostaglandin E2
e. oxytocin
2. In combined oral contraceptives, oestrogens
a. inhibit luteinising hormone (LH) release
b. inhibit follicle stimulating hormone (FSH) release
c. cause increased risk of blood clotting
d. cause thickening of cervical mucus
e. inhibit ovulation
3. Which of the following drugs may be used to stimulate ovulation in
infertile women?
a. ethinyl oestradiol
b. clomiphene
c. bromocriptine
d. follicle stimulating hormone (FSH)
e. luteinising hormone (LH)
4. Thyroxin toxicity includes
a. intolerance to heat
b. diarrhea
c. precipitation of angina pectoris
d. tremor
e. anorexia
5. Synthetic steroids like prednisolone
a. are useful analgesics in the treatment of rheumatoid arthritis
b. are anti-inflammatory
c. *cause diuresis
d. *cause dissolution of lymphoid tissue
e. are useful in the treatment of severe chronic asthma
6. Blood glucose levels in a diabetic patient may be lowered by
a. cigarette smoking
b. subcutaneous injection of adrenaline
c. administration of insulin
d. administration of glucagon
e. administration of codeine
7. Long term prednisolone therapy in humans causes
a. suppression of antibody synthesis
b. hypertension
c. lowered resistance to infection
d. a reduced rate of wound healing
e. increased secretion of ACTH
8. The drug carbimazole diminishes thyroid function by
a. preventing tri-iodothyroxine (T3) and thyroxin (T4) release
b. inhibiting formation of iodinated tyrosyl residues
c. preventing iodine uptake by the gland
d. producing thyroid atrophy
e. inhibiting organic combination of iodine
9. Warfarin
a. is added to blood, which is to be used for transfusion to prevent
coagulation
b. acts by reducing the production of thromboplastins
c. is found naturally in mast cells
d. has its action antagonized by protamine
e. is destroyed in the GIT
Anti-infective agents
10. Sulfonamide antibacterial drugs
a. destroy the bacterial cell wall
b. are bacteriostatic
c. combine with pteridine
d. block utilization of para-amino-benzoic acid (PABA)
e. prevent synthesis of folic acid
11. Which of the following is/are correct about action of penicillin?
a. production of osmotically sensitive bacteria
b. arrest of protein synthesis
c. inhibition of folic acid metabolism
d. inhibition of bacterial cell wall synthesis
e. destruction of mature bacterial cell wall
12. Chloramphenicol
a. only inhibits 70s and not 80s ribosomes
b. binds to bacterial single-stranded DNA
c. inhibits bacterial cell wall synthesis
d. cannot pass through mitochondrial membranes
e. cannot pass through plasma membranes
13. Trimethoprim acts
a. to reduce the supply of 1-carbon units
b. by combining with 80s ribosomes
c. is an antimetabolite
d. by blocking utilization of para-amino-benzoic acid (PABA)
e. by inhibiting bacterial dihydrofolate reductase more than animal
dihydrofolate reductase
14. Which of the following is/are correct about antiviral agents?
a. relapse is common with continued treatment with ganciclovir for
cytomegalovirus retinitis infected AIDS patients
b. ribavirin may be given by aerosol for respiratory syncytial virus
infections
c. amantadine may be given orally in conjunction with influenza
vaccine
d. acyclovir may be given orally for initial genital herpes infections
e. idoxuridine may be applied topically for type 2 genital herpes
infections |