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Q: missy( nizoral and denorex selsun ( Answered 5 out of 5 stars,   0 Comments )
Subject: missy( nizoral and denorex selsun
Category: Science > Chemistry
Asked by: anonymous777-ga
List Price: $100.00
Posted: 29 Jan 2003 13:14 PST
Expires: 28 Feb 2003 13:14 PST
Question ID: 152053
can u compare the denorex shampoo to nizoral and selsun blue
moistureizng shampoo??? which will be better for me ??? which can i
use more offten and is the most mild???

Request for Question Clarification by missy-ga on 29 Jan 2003 13:49 PST
Good afternoon!

I'm pulling the ingredient lists right now.

A once-over of the Nizoral usage instructions states that it should be
used only a couple times a week, for 8 weeks:

"use every 3-4 days for up to 8 weeks if needed, or as directed by a
doctor. Then use only as needed to control dandruff."

Nizoral Anti Dandruff Shampoo

There are some chemicals listed that I haven't seen on any of the
other products I've investigated for you, so this may take a bit of
searching to make sure I have everything for you.  Please bear with me
while I dig these new ones up.


Clarification of Question by anonymous777-ga on 29 Jan 2003 13:58 PST
dont forget about the selsun blue moisturizing treatment as well tha]nks!!!
Subject: Re: missy( nizoral and denorex selsun
Answered By: missy-ga on 29 Jan 2003 18:14 PST
Rated:5 out of 5 stars
Hello Johnny!

I have an answer for you, and has the research today ever been

Let's start with the ingredient lists:

**Denorex Advanced Formula***
Active Ingredients: Pyrithione Zinc 2%  
Inactive Ingredients: Citric Acid, Cocamide MEA, Cocamidopropyl
Betaine, FD&C Blue No. 1, FD&C Yellow No. 5, Fragrance, Glycol
Stearate, Magnesium Aluminum Silicate, Menthol,
Methylchloroisothiazolinone, Panthenol (Pro-Vitamin B5),
Polyquaternium-10, Propylene Glycol, Purified Water, Sodium Laureth
Sulfate, Vitamin E, May Contain Sodium Hydroxide

A detailed description of these ingredients and their uses can be
found on a previous answer:


***Nizoral Anti Dandruff Shampoo*** 
Active Ingredients: Contains: Ketoconazole (1 %)

Inactive Ingredients: Water, Sodium Laureth Sulfate, Cocamide MEA,
Sodium Cocoyl Sarcosinate, Glycol Distearate, Acrylic Acid Polymer
(Carbomer 1342), Fragrance, Sodium Chloride, Tetrasodium EDTA,
Butylated Hydroxytoluene, Quaternium-15, Polyquaternium-7, Sodium
Hydroxide, Hydrochloric Acid, FD&C Blue No. 1

Nizoral Anti Dandruff Shampoo

***Selsun Blue Dandruff Shampoo, Moisturizing Treatment***
Active Ingredients: Per container: Selenium Sulfide Lotion 1%

Inactive Ingredients: Aloe, Ammonium Laureth Sulfate, Ammonium Lauryl
Sulfate, Citric Acid, Cocamide DEA, Ditallow Phthalic Acid Amide
(hydrogenated), Dimethicone, DMDM Hydantoin, FD&C Blue #1, Fragrance,
Hydroxypropyl Methylcellulose, Purified Water, Sodium Citrate, Sodium
Isostearoyl Lactylate, Titanium Dioxide

Selsun Blue Dandruff Shampoo, Moisturizing Treatment 

In previous product evaluations, we discussed the following

Sodium Laureth Sulfate
Cocamide MEA
Glycol Distearate
Sodium Chloride
Tetrasodium EDTA
Sodium Hydroxide
FD&C Blue No. 1
Ammonium Laureth Sulfate
Ammonium Lauryl Sulfate
Citric Acid
Cocamide DEA
DMDM Hydantoin
Hydroxypropyl Methylcellulose

For details of each of these ingredients, please refer to the previous

Compare Chemicals In Shampoos

Tea Tree

American Crew




You can use the Edit-->Find In Page function in the menu bar of your
browser to locate any substance quickly.  Most of them are addressed
on the first answer.  Of course, if you’d like me to re-explain any of
them, just ask and I’ll be happy to do so.

Following are the ingredients which have not previously been

** Nizoral Anti Dandruff Shampoo**

**Ketoconazole (1 %) – a medication, used in this instance to help
control dandruff.  Comes with several precautions.

“Ketoconazole is used to treat skin infections such as jock itch,
athlete's foot, and ringworm; and fungal infections of the
fingernails, toenails, mouth (thrush), lungs, vagina, and blood.


The shampoo is used two times a week, about every 3 days, for 4 weeks.
Follow the directions on your prescription label carefully, and ask
your doctor or pharmacist to explain any part you do not understand.
Take ketoconazole exactly as directed. Do not take more or less of it
or take it more often than prescribed by your doctor.”

The Official Ketoconazole Site 

“Warnings: Adverse effects reported in patients receiving topical 2%
ketoconazole as a shampoo to the scalp include skin irritation,
abnormal hair texture, scalp pustules, dry skin, pruritis (itching),
and oiliness or dryness of the hair or scalp.  There have been reports
that use of 2% ketoconazole shampoo resulted in removal of the curl
from permanently waved hair.  Although there have been rare reports of
increased hair loss, it has not been determined to be directly due to
the use of topical 2% ketoconazole.”

ReGrowth Treatment Shampoo 

See also:

Rx Med - Nizoral Shampoo

Doctor Fungus – Ketoconazole 


**Sodium Cocoyl Sarcosinate – a coconut derivative.  Very mild.

“Sodium cocoyl sarcosinate is a derivative of coconut oil and the
amino acid, sarcosine. It is skin friendly and has the unusual ability
of producing a very rich lather in the presence of oil- the more oil,
the richer the lather!”


**Acrylic Acid Polymer (Carbomer 1342)  - I have not been able to find
a satisfactory explanation of what this substance is or why it is in
this shampoo.  I did, however, find a reference in a women’s hair loss

“I have not heard of burning scalp, but if you have used Nizoral 1%
you will notice thaat Acrylic acid Polymer is the 1st. inactive
ingredent. It's also used as a floor polish and many other industrial
uses AND is known as a skin and eye irritant”

Scalp Dyesthesia 

**Butylated Hydroxytoluene – also called BHT.  A preservative.

“An antioxidant and preservative used to prevent oils from turning

Make Your Own Cosmetics Glossary

**Quaternium-15 – a preservative and conditioning agent:

“Preservative used in cosmetics. Water soluble anti microbial agent
that fights bacteria. A quaternary ammonium salt”

“Quaternary Ammonium Salts (QUATS)
Quats comprise a large number of substances that are used extensively
as surfactants and antimicrobial agents. Compounds are quaternaries
only if they contain at least one nitrogen atom linked to four (Latin:
quater) alkyl or aryl groups. Many QUATS provide excellent
conditioning and antistatic properties making them the ideal hair

Make Your Own Cosmetics Glossary

**Hydrochloric Acid – a corrosive acid.  This is the same acid found
in the stomach.  Apparently, it’s used in this product as a solvent:

“hydrochloric acid

Also known as niliriaric acid, this corrosive chemical is present in
gastric juice (in dilute form) and is used in cosmetics as an oxidant
and solvent. It’s also used in nail bleach. Inhaling its fumes can
irritate mucous membranes.”

Skin Care Guide

I also found reference to the use of HCL in the preparation of hair
for hairpieces:

“Once the hair arrives at the factory, it is treated in a hydrochloric
acid bath to remove the cuticle. A word of warning - hydrochloric acid
is extremely hazardous. Please do not put yourself at risk by
experimenting with this chemical! But back to the problem. It’s not
the remy hair; remy hair is relatively easy to process and the damage
inflicted during de-cuticalization is slight.”

Non-Surgical Hair Restoration - What You Don’t Know Can Hurt You! 

**Selsun Blue Dandruff Shampoo, Moisturizing Treatment**

**Selenium Sulfide Lotion 1% (Antidandruff) – an anti-seborrheic
medication.  It comes with several precautions:

“Before Using This Medicine:
If you are using this medicine without a prescription, carefully read
and follow any precautions on the label. For selenium sulfide, the
following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or
allergic reaction to selenium sulfide. Also tell your health care
professional if you are allergic to any other substances, such as
preservatives or dyes.


Other medicines—Although certain medicines should not be used together
at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may
want to change the dose, or other precautions may be necessary. Tell
your health care professional if you are using any other topical
prescription or nonprescription (over-the-counter [OTC]) medicine that
is to be applied to the same area of the skin.



The dose of selenium sulfide will be different for different patients.
Follow your doctor's orders or the directions on the label. The
following information includes only the average doses of selenium
sulfide. If your dose is different, do not change it unless your
doctor tells you to do so.

    * For lotion dosage form:
          o For dandruff or seborrheic dermatitis:
                + Adults and children—If you are using the 1% lotion,
use on the scalp two times a week. If you are using the 2.5% lotion,
use on the scalp two times a week for two weeks, then use one time a
week or less often.


Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted
effects. Although not all of these side effects may occur, if they do
occur they may need medical attention.

Check with your doctor as soon as possible if the following side
effect occurs:
Less common or rare:  Skin irritation  

Other side effects may occur that usually do not need medical
attention. Check with your health care professional if any of the
following side effects continue or are bothersome:
More common:  Unusual dryness or oiliness of hair or scalp  
Less common:  Increase in normal hair loss”

Selenium Sulfide – Medline Plus 

**Ditallow Phthalic Acid Amide (hydrogenated) – unknown.  I cannot
locate anything which explains this substance.

**Sodium Citrate – a salt used as a stabilizer and to reduce acidity

“Sodium citrate - This crystalline salt is used in cosmetics as a
sequestrant and an alkalizer, and in foods as a buffering agent.”

Skin Care Guide

**Sodium Isostearoyl Lactylate – a conditioner and moisturizer,
derived from lactose (milk sugar)

“Sodium Isostearoyl Lactylate (a lactose based skin conditioner which
duplicates skin's naturally occurring moisturizers)”

Massage Specialists

**Titanium Dioxide – used for coloring and opacity (makes the product
opaque or not see-through)

“titanium dioxide

This white powder is used as a pigment in eye makeup, sunscreens and
foundation makeup (both powdered and liquid). It’s also used as an
opacifying agent, for its covering power, brilliance and reflectivity.
An inorganic salt that’s also used in house paint, enamels, plastics,
paper products and shoe whiteners, titanium dioxide shouldn’t be

Skin Care Guide


In comparing the three shampoos, I found myself quite alarmed by what
I was reading about the ingredients in the Nizoral shampoo.  Though
very mild conditioning agents are present, such as Sodium Cocoyl
Sarcosinate and Quaternium-15, the active ingredient, Ketoconazole,
may produce "skin irritation, abnormal hair texture, scalp pustules,
dry skin, pruritis (itching), and oiliness or dryness of the hair or
scalp".  Additionally, the inexplicable inclusion of Hydrochloric Acid
and Acrylic Acid Polymer, both of which are definite irritants, is
rather worrisome.

The possible side effects of the active ingredient and the
inexplicable inclusion of corrosive substances, combined with the
standard inclusion of Sodium Laureth Sulfate and Cocamide MEA, both of
which are somewhat drying, lead me to believe that this product is
probably not a good choice for you.

If you choose to use it, do so cautiously and exactly according to the
package instructions.

The Selsun Blue, while it does have a questionable ingredient
(Ditallow Phthalic Acid Amide, for which I could find no description),
offers Aloe as its primary ingredient.  Aloe is well known for its
soothing and moisturizing properties.  Its active ingredient, Selenium
Sulfide, may cause some side effects if used incorrectly; these side
effects appear to be considerably less bothersome.

The formula does include surfactants known to be somewhat drying
(Ammonium Laureth Sulfate, Ammonium Lauryl Sulfate, Cocamide DEA), but
they are in smaller proportions than the Aloe.

This formula is a better choice for you than the Nizoral, as long as
it is used exactly as the package directs.

Of the three, however, I would be more inclined to go with the Denorex
if you intend to use a dandruff shampoo daily, and are continuing to
use Rogaine.  In research over the past two days, I've found no
interaction warnings for Pyrithione Zinc (Denorex's active ingredient)
and no indication that it has any side effects.  There have been no
indications that it might cause drying of the hair or scalp, and no
cautions that one should consult a doctor before using it.  Further,
the formula contains Panthenol, Polyquaternium-10, Propylene Glycol
and Vitamin E, which are beneficial in helping maintain moisture in
both hair and skin.

The Denorex Advanced formula appears to be the milder choice for daily

If I can be of further assistance, please don't hesitate to ask for
clarification.  I'll be at my desk until about 2AM EST tonight, and
back again around 3PM EST tomorrow.


Search terms:  Listed ingredients

Request for Answer Clarification by anonymous777-ga on 30 Jan 2003 11:18 PST
what are all the "hasrh and drying" chemicles in selsun blue again and
can u do another compare chemiclas with t-gel normal version, thanks

Clarification of Answer by missy-ga on 30 Jan 2003 11:43 PST

The ingredients known to be somewhat drying or irritating in Selsun
Blue are Ammonium Laureth Sulfate, Ammonium Lauryl Sulfate, Cocamide
DEA, and DMDM Hydantoin (which releases formaldehyde, which is known
to cause allergic reactions in some individuals.

The T-Gel shampoo is made by Neutrogena, yes?  I'll get right on that!


Clarification of Answer by missy-ga on 30 Jan 2003 13:40 PST
Hello Johnny!  How are you today?

Let’s have a look at Neutrogena’s T-Gel Shampoo:

Active Ingredients: 2% Neutar Solubilized Coal Tar Extract (0.5% Coal

Inactive Ingredients: Purified Water, Sodium Laureth Sulfate, Cocamide
DEA, Laureth-4, Fragrance, Cocamidopropyl Betaine, Imidazolidinyl
Urea, Methylparaben, Propylparaben, Sodium Chloride, Citric Acid,
Tetrasodium EDTA

Neutrogena T-Gel Shampoo, Original 

Neutrogena T-Gel shampoo has long been touted as a safe, gentle
treatment for dandruff and other scalp ailments.  In fact, over the
years, Neutrogena has become synonymous with “gentle” – their soaps
and shampoos are highly recommended for acne and allergy sufferers,
and are even used in nursing homes in the care of the elderly (who
tend to suffer from very dry skin).

Because T-Gel is a medicated shampoo, it does come with some
precautions, notably:

“Use caution in exposing skin to sunlight after applying this product
.  It may increase your tendency to sunburn for up to 24 hours after
application.  Do not use for prolonged periods without consulting a
physician.  Do not use this product with other forms of psoriasis
therapy such as ultraviolet radiation or prescription drugs unless
directed to do so by a physician.”

Of the ingredients listed, we’ve already discussed the following:

Purified Water
Sodium Laureth Sulfate
Cocamide DEA
Cocamidopropyl Betaine
Sodium Chloride
Citric Acid
Tetrasodium EDTA

Descriptions of the above ingredients can be found on the other
answers, but I will be happy to re-explain any of them you’d like. 
Just ask!

That leaves us with:

**Coal Tar Extract – a coal derivative, used to treat dandruff and
other skin ailments.

According to MedLine Plus Drug Information:

“Coal tar is used to treat eczema, psoriasis, seborrheic dermatitis,
and other skin disorders.


Proper Use of This Medicine

Use this medicine only as directed

After applying coal tar, protect the treated area from direct sunlight
and do not use a sunlamp for 72 hours, unless otherwise directed by
your doctor, since a severe reaction may occur. Also, make sure you
have removed all the coal tar medicine from your skin before you go
back into direct sunlight or use a sunlamp.

Do not apply this medicine to infected, blistered, raw, or oozing
areas of the skin”


For shampoo dosage form:

 Adults—Use once a day to once a week or as directed by your

Coal Tar (Topical) 

Coal tar is one of only five ingredients certified by the FDA as safe
and effective for use in controlling dandruff and other skin ailments:

FDA Consumer 10/01/1994

**Laureth-4 – an “ethyloxylated alcohol”, derived from coconut. 
Laureth 4 is a surfactant and “dispersant” (allows product to flow

Laureth 4

**Imidazolidinyl Urea – also spelled “Inaidazolidinyl” - an

“Inaidazolidinyl Urea - A by-product of human metabolism used as an
anti microbial agent.”

Make Your Own Cosmetics Glossary

As with the other shampoos compared, there are some ingredients which
may cause drying: Sodium Laureth Sulfate, Cocamide DEA, Cocamidopropyl
Betaine.  They are, however, listed as mild or “low irritant”, and are
less drying than other common surfactants (such as the *Lauryl
Sulfates).  Most shampoos on the market today contain at least one of
these surfactants, some contain several.  As long as you use your
shampoos according to package directions, the drying effect should be
minimal (if any).

Neutrogena’s active ingredient has been listed in several references
as effective for treating dandruff, is certified by the FDA, and
appears to have very minimal side effects – namely some UV
sensitivity.  (This is easily remedied by wearing a hat outdoors.) 
T-Gel comes highly recommended from sites such as and
The Bald Truth as a mild, safe solution for dandruff control.

Like Denorex, Neutrogena T-Gel bills itself as mild enough for daily
use.  I’ve found nothing in my research that would indicate otherwise.
 Both are mild, and the active ingredients cause minimal to no side

The Bald Truth, a site dedicated to dealing with hair loss, recommends
that medicated shampoos be used no more than three times a week, which
is consistent with most package instructions, and alternated with a
moisturizing shampoo:

“Note: After initial use, The Bald Truth recommends a maintenence
regimen. The use of either medicated shampoo should not be used more
than 3x per week, but should be used consistently to maintain

Click “Shampoo Rotation” link 

This is apparently to allow you the chance to give your scalp a break
from the medication, and allow you to use your favorite moisturizing
or conditioning shampoo in rotation.

I hope this helps!  If you need further assistance, just ask!


Search terms:  listed ingredients
anonymous777-ga rated this answer:5 out of 5 stars and gave an additional tip of: $50.00

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