I need to know whether others once-a-day products like ZYDOL XL
(marketed by Pharmacia) and Dromadol XL (marketed by IVAX), are on the
market (any country) or not. I am looking for neither twice daily
tramadol products, nor "standard" tramadol products (three or four
times a day), but ONCE-A-DAY tramadol products, like ZYDOL XL and
DROMADOL XL, which are both currently on the market in the UK.

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Clarification of Question by tom136-ga on 26 Feb 2003 01:56 PST

maybe "controlled release", "extended release", "sustained release",
"long action" terms can be of help for the search.

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Clarification of Question by tom136-ga on 26 Feb 2003 02:32 PST

I would like to identify a product(s) like stated in the question, in
ANY COUNTRY around the world.
Thanks!

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Clarification of Question by tom136-ga on 26 Feb 2003 02:37 PST

I need the answer in the next 2 hours. If I don't get the answer by
then, unfortunately I 'll have to close the question. Thanks!

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Request for Question Clarification by czh-ga on 26 Feb 2003 07:50 PST

It is past your original deadline. Are you still interested? Is there
a new deadline? Thanks.

czh

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Clarification of Question by tom136-ga on 26 Feb 2003 08:35 PST

Hi czh, 
Well, yes. Now I could wait until tomorrow until this time (around 24
hs from now). But I would like to point out that I will accept as a
valid answer only the reference to once-daily tramadol product(s) on
the market (except in the UK), and not drugs or products which are
currently under development.
Said that, I would like to thank you for your effort, which I
appreciate very much.
Kind regards! 
Tom136

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Clarification of Question by tom136-ga on 26 Feb 2003 12:56 PST

Hi czh-ga.
Thank you very much for your effort! Yes, I knew the info about the trials.
Kind regards,
Tom136

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Clarification of Question by tom136-ga on 26 Feb 2003 13:04 PST

Hi, I was able to find another once-a-day tramadol product. It is
marketed in Spain by Zambon, under the name Zytram.
http://www.zambon.es/visita_vade/vademecum/vadem/zytram.htm
Thus, I will close the question.
Thank you very much to everyone who had a look to this question, and
tried to answer it.
Search strategy employed: 
I found it using a kind of "chain search" strategy:
1) I used "once-daily tramadol" (the first result mentioned "Napp
Pharmaceuticals"
2)I searched using: Napp AND tramadol
3)In one of the results I found the word Zytram. 
4)I used that name to find out that it is marketed in Spain, and
perhaps in Italy.

Regards,
Tom136

Hello tom136-ga,

I'm not posting this as an answer because I haven't had time to
research which of these products are the once-daily formulation, but
here's a table that shows you all the different names tramadol goes by
and the various drug companies associated with each name.

http://www.ic-network.com/glossary/glossarypain.html
You are here: IC Network > Drug Glossary > Pain Medications
Oral Medications - Pain Medications
Tramadol
Brand Name: Ultram
Manufacturer(s): Allegiance/Allscrips , Ortho McNeil Pharmaceuticals
Clinical Pharmacology: Opioid Analgesic - moderate to moderately
severe pain
Related Research & Web Sites: Drug Monograph
Possible Side Effects: Headache, dizziness, sleepiness. nausea
Availability in Other Countries:
Country -- Drug Name -- Manufacturer

I'll keep looking in hope that I can beat your deadline.

Good luck.

czh

Dear cyh-ga: many thanks for the link. However, it does not answer
what I am looking for. I have already an extensive listing of
trademarks with tramadol products, but I would like to find others
tramadol once-a-day formulation currently on the market(apart from
ZYDOL XL and Dromadol XL, which are marketed in the UK). I know that
some formulations are being tested in the US, Europe and Japan, but
what I am looking for is another/others currently marketed once-a-day
tramadol products, in the world (except UK). The links seems not to be
updated for a long time.
Anyway, thanks again.
Tom136

Hi czh,
Well, yes. Now I could wait until tomorrow until this time (around 24
hs from now). But I would like to point out that I will accept as a
valid answer only the reference to once-daily tramadol product(s) on
the market (except in the UK), and not drugs or products which are
currently under development.
Said that, I would like to thank you for your effort, which I
appreciate very much.
Kind regards!
Tom136

Hello again tom136-ga,

I took another look and reviewed the literature for tramadol products
under the following names: Adolonta , Nobligan, Tramal, Contramal,
Dolzam, Theradol, Tiparol, Topalgic, Tralgiol, Tramadolar, Tramagetic,
Tramake.

None of them come in the once-a-day version. As you already know, both
recent US and European trials have gone well and it’s anticipated that
the once-a-day tramadol products will be approved in 2003. I’m sorry I
couldn’t come up with anything.

czh