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Q: medical research allergy treatment ( Answered 5 out of 5 stars,   0 Comments )
Question  
Subject: medical research allergy treatment
Category: Health > Conditions and Diseases
Asked by: pragmaticaaa-ga
List Price: $10.00
Posted: 26 Apr 2003 00:19 PDT
Expires: 26 May 2003 00:19 PDT
Question ID: 195660
all clinical trials medical reseach  double blind studies on enzyme
potentiated desensitization for food allergy
Answer  
Subject: Re: medical research allergy treatment
Answered By: bcguide-ga on 07 May 2003 02:43 PDT
Rated:5 out of 5 stars
 
Hi,

I'm not sure that anyone can give you a list of ALL clinical medical
research on this topic. However, searching Pub Med for EPD results in
15 pages of citations with 20 studies on each page. Most are from the
1990s, but the latest were published in 2002. This link will lead you
to the results:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Display&dopt=pubmed_pubmed&from_uid=11913061

According to an article in "The Ear Nose & Throat Journal
http://www.findarticles.com/cf_0/m0BUM/3_81/84540935/p1/article.jhtml?term=EPD
"McEwen Laboratories is actively working to satisfy all FDA
requirements to eventually gain approval for routine use of EPD by
physicians in the United States. An investigational study to evaluate
the effectiveness of EPD in the treatment of hay fever is being
developed. We anticipate that the study will start sometime in 2003."

Looking for current clinical trials is less helpful.

The National Institutes of Health has a listing of clinical trials in
the US. None fit the category you are looking for. You might keep
track to see if one comes up.
http://www.clinicaltrials.gov/

They also have studies at:
http://clinicalstudies.info.nih.gov/

Entering food allergy in the search give 53 studies about food - none
of which are on food allergies
(http://clinicalstudies.info.nih.gov/cgi/processqry3.pl?sort=1&search=food&searchtype=0&patient_type=All&protocoltype=All&institute=%25&conditions=All)
and 8 for allergies (http://clinicalstudies.info.nih.gov/cgi/processqry3.pl?sort=1&search=allergy&searchtype=0&patient_type=All&protocoltype=All&institute=%25&conditions=All)
none of which apply to your question.

National Institutes of Allergy and Infectious Diseases (NIAID)lists
clinical trials (http://www.niaid.nih.gov/clintrials/) again, none for
food allergies.

CenterWatch is another database of clinical trials
(http://www.centerwatch.com/search.asp) they list one that might be
relevant:

Radiant Research http://www.protocaretrials.com/participate.asp is
doing allergy studies, but does not list the studies. You can fill in
your information and they will contact you if you match the criteria
for any of their trials.

"The metaRegister of Controlled Trials is a searchable, international
database of ongoing randomised controlled trials in all areas of
healthcare. At present, the mRCT also contains some completed trials.
Offering access to more than 14,000 records, the mRCT is free."
http://www.controlled-trials.com/

Peanut allergies provoking medical symptoms (P.A.C.S) - the trial is
completed. Contact details  University Child Health, G level, Centre
Block
Southampton General Hospital
Tremona Road
Southampton
SO16 6YD
United Kingdom 
http://www.controlled-trials.com/mrct/trial/FOOD/1046/38457.html

Double-blind, placebo-controlled food challenge using enteric-coated
sulphite capsules in patients with suspected sulphite sensitivity
Mrs IJ Skypala 
Contact details  Nutrition & Dietetics
Royal Brompton & Harefield NHS Trust
Sydney Street
London
SW3 6NP
United Kingdom
Tel: 020 7351 8079
Fax: 020 7351 8990
Email: I.Skypala@rbh.nthames.nhs.uk 
http://www.controlled-trials.com/mrct/trial/FOOD/1046/23091.html

It isn't clear that either of these two use EPD, but they may have.

The FDA does not list any current activity in regard to research
trials for approval of EPD.
http://www.fda.gov/ora/orasrch.htm

They have lifted the ban on importing it for personal use according to
one site:
http://www.epdallergy.com/personal_importation.htm

A 1999 article from Medical Economics Magazine asks, "Was this doctor
"unconventional" enough to lose his license.(includes related articles
on his case and his unconventional methods)(internist Robert J.
Sinaiko)." The article gives some information on a California doctor
who was involved in legal action due to prescribing EPD and other
alternative treatments.
http://www.findarticles.com/cf_0/m3229/12_76/55174883/p1/article.jhtml?
term=Enzyme-potentiated+desensitization 

The Townsend Letter for Doctors and Patients adds comments on this
case.
http://www.findarticles.com/cf_0/m0ISW/2002_August-Sept/90794468/p2/article.jhtml?term=Enzyme-potentiated+desensitization


Search terms: 
EPD
clinical trials database
Enzyme-potentiated desensitization

Hope this helps.

Regards,
bcguide-ga
pragmaticaaa-ga rated this answer:5 out of 5 stars and gave an additional tip of: $5.00
excellent thank you

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