hi tom136,
Here is a list of companies involved in nasal drug delivery:
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Aventis Pharma UK
"Nasal Delivery Platforms - There are several formulation and product
approaches. Namely, Aerosols - propellant driven (solution and
suspensions), Aerosols - aqueous sprays & pumps (solution and
suspensions), Powders – device options are available.
For all of the options there are Aventis Delivery Technologies
available. We have a number of products available and currently market
both aqueous solutions and pressurised nasal products..."
http://www.aventispharma.co.uk/main/0,1003,EN-GB-29940-48171--,00.html
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MatTek Corporation
"...The nasal route is an attractive alternative to conventional oral
or parenteral drug delivery. The nasal mucosa provides a moist and
highly vascularized membrane, crucial to rapid absorption into the
blood stream, thus facilitating faster transport to the site of
action. The two main disadvantages of nasal delivery are the limited
maximum dose per spray and the rapidity of clearance from the nasal
cavity. These difficulties can best be addressed early in drug
development. In vitro screening of drug formulations can provide an
efficient and cost-effective method of identifying lead candidates
prior to in vivo testing. We have evaluated the ability of a large
number of drug formulations to penetrate mucous membranes using
MatTek's EpiAirway™ System..."
http://www.mattek.com/pages/news/wn008
-----------------------------------
BD Pharmaceutical Systems
"BD Pharmaceutical Systems is the industry leader in providing
quality, prefillable parenteral drug delivery systems for the
pharmaceutical industry. Whether it's a prefilled syringe, nasal drug
delivery device, IV infusion system, diluent syringe, dry drug
reconstitution system, a safety needle or the latest in self-injection
technology, BD delivers."
http://www.bd.com/pharmaceuticals/
-----------------------------------
Bespak
"Bespak, founded more than 40 years ago, has established a reputation
as a leading supplier of drug delivery technologies and services to
the pharmaceutical and biotechnology industries.
The company’s comprehensive capabilities have enabled it to develop
proprietary drug delivery devices and technologies, many protected by
worldwide patents. These include pressurised metered dose inhalers and
actuators, dose counters, breath co-ordinated and breath-activated
devices, dry powder inhalers and electrostatic atomisation and a range
of unit and multi-dose, liquid and dry powder nasal devices..."
http://www.bespak.co.uk/company.asp?id=25
-----------------------------------
Lyfjathróun Biopharmaceuticals
"Our technical collaboration with Lyfjathroun continues to exceed
expectations. As a result of this success, we have reached agreement
with this Reykjavik-based nasal drug formulation business to undertake
a much more extensive programme based on proprietary formulation
technology licensed to Bespak. The new agreement, which works on three
systemically acting drugs, accelerates our Nasal strategy while
decreasing its risk"
http://www.lyf.is/news/index.html
-----------------------------------
Optinose
"OptiNose is a Norwegian R&D company developing innovative devices for
nasal delivery of vaccines and drugs (liquid and powder) with topical
or systemic action..."
http://www.optinose.no/
-----------------------------------
West Pharmacuticals
"West is a leader in nasal delivery. West's technologies allow
enhanced systemic or local drug delivery for a variety of diseases..."
http://www.westpharma.com/drug%20delivery/nasal_delivery.asp
-----------------------------------
CIIT Centers for Health Research
"Bespak (LSE:BPK), the innovator of drug delivery technologies, and
the CIIT Centers for Health Research, a leader in respiratory and
inhalation science, have today announced the initiation of a
significant research collaboration in the area of nasal drug
delivery..."
http://www.ciit.org/News/Bespak
-----------------------------------
Meridica
"...Xcelonase™ is Meridica’s nasal drug delivery device and is
currently at an early stage of development. Xcelonase will be designed
to exceed the market standards in nasal drug delivery and will be
suitable for a wide range of formulations. It is suitable for nasal
delivery in both adults and children..."
http://www.meridica.com/technology.html
-----------------------------------
New Millennium Pharmaceutical Research Inc
Dittert and Hussain developed the nasal spray at their company, New
Millennium Pharmaceutical Research Inc., at Advanced Science and
Technology Commercialization Center on the UK campus.
http://www.nextdaymedications.com/viagra-nasal-spray.htm
* I could not find an official website for New Millennium
Pharmaceutical Research Inc. but i found the following telephone
number:
New Millennium Pharmaceutical Research Inc. (NMPRI) TEL:257-2300, ext.
298 Advanced Science and Technology Commercialization Center
University Of Kentucky
-----------------------------------
Intranasal Technology, Inc. (ITI)
"Intranasal Technology, Inc. (ITI) is a development-stage
pharmaceutical and drug delivery company focused on capitalizing on
the advantages of administering prescription drugs into the human body
through the nasal cavity..."
http://www.intranasal.com/about.html
-----------------------------------
Pharmaceutical Profiles Ltd
"Pharmaceutical Profiles uses sophisticated product visualization
techniques to establish precisely how radiolabelled oral, pulmonary,
nasal, rectal or vaginal technologies deliver drugs to healthy human
volunteers and patients..."
http://www.pharmprofiles.com/what.htm
-----------------------------------
Aviron (Acquired By MedImmune, Inc.)
"FluMist™ (Influenza Virus Vaccine Live, Intranasal) is an
investigational live, attenuated vaccine delivered as a nasal mist
being developed for the prevention of influenza..."
http://www.aviron.com/pipeline/flumist.asp
-----------------------------------
Health Advances
"HA Experience in Biotechnology and Pharmaceuticals ...
Nasal drug delivery"
http://www.healthadvances.com/bio_pharm.html
-----------------------------------
Next Breath LLC
"Our mission is to serve as an effective liaison between innovators of
promising drug molecules and inventors of pulmonary and nasal drug
delivery devices. Next Breath can test that drug/device combination
under conditions satisfactory to regulatory agencies, while helping to
ensure the end product is acceptable to patients and clinicians..."
http://nextbreath.net/home.html
-----------------------------------
Schwartz Pharma AG
"Hauppauge, NY and Mequon, WI (January 7th, 1997) Nastech
Pharmaceutical Company, Inc. (NASDAQ: NSTK) and SCHWARZ PHARMA, Inc.
(ADR: SWPHY) today jointly announced that they have entered into an
agreement for U.S. marketing rights to Nastech's intranasal
scopolamine gel, which is expected to be the first scopolamine agent
indicated for both prevention and treatment of motion sickness."
http://www.schwarzpharma.com/index.php?node_id=310
-----------------------------------
I hope this helps!
regards,
Jack
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