The answer to your question is yes. I searched under "FALSE POSTITIVE
FOR DEMEROL URINE" and found the following:
Substances that may show up in your drug test known as "False
Athletes and hopeful job applicants often hinge their careers on a
clean drug test, but the use of certain antibiotics may cause an
unsuspecting person to test positive for heroin even though they've
never touched the drug.
Researchers led by Dr. Lindsey R. Baden of Harvard Medical School in
Boston, Massachusetts, investigated this problem after they came
across a patient in their practice who tested positive for opiates,
and who was also taking an antibiotic called levofloxacin. The patient
was nearly kicked out from a drug treatment center because of the
result, which later proved to be false.
Opiates are a class of drugs that include the illegal drug heroin, and
several other controlled drugs such as methadone, morphine, Demerol
In their study, Baden and colleagues tested 13 different types of
antibiotics, including levofloxacin and Cipro, all belonging to a
class of chemicals called quinolones, to see what effect they would
have on commercial opiate tests.
The researchers diluted the antibiotics to concentrations that would
be expected to occur in urine and then tested the antibiotic samples
using five different commercial tests to see if they would cause a
positive result for opiates.
Two antibiotics, levofloxacin and ofloxacin, caused a strong positive
result on four of the five tests.
Most of the other antibiotics also caused a positive result on at
least two or three of the five tests. For example, Cipro, the drug
given to thousands of people to fight possible anthrax exposure,
resulted in a positive test in one out of the five tests.
To confirm these results in people, they had six people take a
standard dose of one of the two antibiotics and collected their urine
samples every 6 hours for the next 48 hours.
On one of the five tests, all three patients taking levofloxacin
tested falsely positive within 2 hours and up to 22 hours after taking
the drug. The results were similar in patients taking ofloxacin, the
investigators report in the December 26th issue of The Journal of the
American Medical Association.
Baden told Reuters Health that he suspects that the false positives
result from the similar three-dimensional structures of opiates and
the antibiotics. He also pointed out that other types of chemicals
could cause a similar reaction.
According to Baden, it is possible that people have suffered
consequences of a false positive test, because ``a positive drug test
is often assumed true, while the protestations of the person being
tested are looked at as self-serving.''
Baden recommends that anyone who tests falsely positive for opiates
ask to have drug testing performed to confirm the result.
Substances in drug testing that may show a "False Positive"
Over-the-counter cold and allergy remedies that contain ephedrine,
pseudoephedrine, propylephedrine, phenylephrine or desoxyephedrine:
Nyquil, Contactd, Sudafed, Allerest 12-Hour, A.R.M., Triaminic 12,
Ornade, Tavist-D, Dimetapp, Sinex, Neosynephrine, Actifed, Bayer
Selectd Maximum Strength Sinus Pain Relief Caplets, Contact Non-Drowsy
Formula Sinus Caplets, Dristan Cold Caplets, Maximum Strength Sine-Aid
Tablets, Maximum Strengeth Sudafed Sinus Caplets, Maximum Strength
Tylenol Sinus Gelcaps, No Drowsiness Sinarest Tabs, Sinus Excedrin
Extra Sterength Caplets, Characol Sinus, Drixoral Cold and Flu,
Efidac/24, Phenegan-D, Robitussin Cold and Flu. Over-the-counter diet
aids containing phenylpropanolamine: Dexatrim, Accutrim.
Over-the-counter nasal sprays: Vicks inhaler, Afrin. Asthma
medication: Marax, Bronkaid tablets, Primatine Tablets. Prescription
medication: Amfeprainone, Cathne, Etafediabe, Morazone,
phendimetrazine, phenmetrazine, benzphetamine, fenfluramine,
dexfenfluramine, dexdenflurarnine, Redux, mephentermine, Mesocarb,
methoxyphenamine, phentermine, amineptine, Pholedrine,
hydroymethamphetamine, Dexedrine, amifepramone, clobenzorex,
fenproyorex, mefenorex, fenelylline, Didrex, dextroamphetamine,
methphenidate, Ritalin, pemoline, Cylert, selegiline, Deprenyl,
Over-the-counter NSAIDS: lbuprofen; Advil, Nuprin, Mediprim, Motrin,
Bayer Select Pain Relief Formula, Excedrin IB Caplets, Genpril,
Haltran, lbuprin, Midol 200, Pamprin, Trendar Cramp Relief Formula,
Cramp End Tablets, Medipren, Rufln, Naproxen, Aleve, Ketoprofen,
Orudis KT. Prescription NSAIDS: Anaprox, Tolectin, ifenoprofen,
flurbiprofen, oxaprozin, Ansaid, Clinoril, Dolobid, Feldene, Indocin,
Lodine, Meclomen, Motrin, Nalfon, Naprosyn, Orudis, Relafen, Voltaren.
Over-the-counter allergy preparations, sleep aids and antinausea
medications that contain promethazine: Phenergan, Promethegan.
Riboflavin (vitamin B2), Dronabinol, Edecrin.
Amoxicillin, tonic water
Poppy seeds, Emprin, Tylenol with codeine, Capital with codeine,
Margesic, rifampicin, Vicodin, Percodan, Percocet, Wygesic.
Fiorinol, Donnatol, some sleeping pills, antiasthmatic preparations
that contain phenobarbitol, Dilantin.
Most prescription sleeping pills and anti-anxiety medication.
Migraine medication: egotamine, Ergostat, Cafergot, Wigraine,
Imitrex. Hydergine, bromocription, methysergiside, lisuride, lysergol,
Artane, triprolidine, amitriptyline (Elavil), dicyclomine (Bentyl),
antinausea medications that contain promethazine: Phenergan,
This apparently is a very serious problem and many people are being
falsely accused of drug use when they are absolutely innocent.
I hope this information helps you out, Redhoss