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The cervix, whilst often a primary site of cancer development, is not
a common site for metastasis of other primary tumors. Breast tumors
appear to be capable of this rare feat (primarily lobular type breast
cancer and signet ring breast cancer) as are ovarian cancers.
Epithelial tumors are also apparently capable (see reference 7)
Abstracts of case reports of breast cancer to the cervix (articles not
available online):
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11269991&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9432828&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9250327&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9684585&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9639771&dopt=Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10518190&dopt=Abstract
Abstracts of ovarian cancer to cervix, article not available online:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3988124&dopt=Abstract
Case reports of breast cancer metastatic to cervix available online
with a subscription:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9887251&dopt=Abstract
Other references to case reports and reviews of the literature, for
which even an abstract is not available online:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10489810&dopt=Abstract
1. Stemmerman GN: Extrapelvic carcinoma metastatic to the uterus. Am J
Obstet Gynecol 82:12611266, 1961
2. Yazigi R, Sandstad J, Munoz AK: Breast cancer metastasizing to the
uterine cervix. Cancer 61:2558 2560, 1988
3. Merino MJ, Livolsi VA: Signet ring carcinoma of the female breast:
a
clinicopathologic analysis of 24 cases. Cancer 48:1830 1837, 1981
4. Fiorella RM, Beckwith LG, Miller LK, Kragel PJ: Metastatic signet
ring
carcinoma of the breast as a source of positive cervicovaginal
cytology.
Acta Cytol 37:948 952, 1993
5. Piura B, Bar-David J, Goldstein J: Abnormal uterine bleeding as a
presenting
sign of metastatic signet ring cell carcinoma originating in the
breast: case report. Br J Obstet Gynaecol 92:645 648, 1984
6. Mazur MT, Hsueh S, Gersell DJ: Metastases to the female genital
tract:
analysis of 325 cases. Cancer 63:593596, 1984
7. Lemoine NR, Hall PA: Epithelial tumors metastatic to the uterine
cervix:
a study of 33 cases and review of the literature. Cancer 57:20022005,
1986
8. Abrams HL, Spiro R, Goldstein N: Metastases in carcinoma: analysis
of
1000 autopsied cases. Cancer 3:7485, 1950
9. Kumar NB, Hart WR: Metastases to the uterine corpus from
extragenital
cancers. Cancer 50:21632169, 1988
10. Banoono F, Labes J, Goodman PA: Uterine leiomyoma containing
metastatic
breast carcinoma. Am J Obstet Gynecol 111:427 430, 1971
Please let me know if you have further questions.
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