Hello there
Due to the nature of your question you will be getting a lot of
quotes. It is our policy not to use quotes heavily but in this case I
hope I will be forgiven as the information contained is sensitive and
paraphrasing is certain to lead to errors.
1 - "What you need to know about ZOTON
Please read this leaflet carefully before you start to take your
medicine. It does not tell you everything about your medicine. If you
have any questions, please ask your doctor or chemist (pharmacist).
Keep this leaflet while you are taking your ZOTON. You may want to
read it again.
Things to remember about your medicine
As well as helping you, a medicine may have some effects you don’t
want. You can find more information about this in this leaflet.
Take your medicine exactly as your doctor tells you.
Keep taking your medicine until your doctor tells you to stop.
Keep your medicine where children cannot see or reach it.
To find out more about your medicine, please read on.
What’s in your medicine?
The active ingredient of ZOTON is Lansoprazole. Lansoprazole belongs
to a group of medicines known as proton pump inhibitors. ZOTON
Capsules come in two strengths containing either 15mg or 30mg of the
active ingredient lansoprazole. Each strength of capsule is a
different colour; 15mg capsules are yellow, 30mg capsules are two tone
lilac/purple. ZOTON Suspension 30mg is provided as gastro-resistant
granules for oral suspension. It is available as a single dose sachet
containing 30mg of the active ingredient lansoprazole. Each sachet
contains granules which should be mixed well with two tablespoons
(30ml) of tap water. When mixed with water the granules produce a pink
suspension with a strawberry flavour. ZOTON Capsules also contain the
following ingredients: Magnesium carbonate, sucrose, maize starch, low
substituted hydroxypropyl cellulose, hydroxypropylcellulose,
methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30 per
cent, talc, macrogol, titanium dioxide, polysorbate 80, colloidal
anhydrous silica, gelatin and colours: Opacode black ink and E171 plus
either E127 and E132 (30mg capsules) or E172 (15mg capsules). ZOTON
Suspension also contains the following ingredients: Magnesium
carbonate, sucrose, maize starch, low substituted hydroxypropyl
cellulose, hydroxypropylcellulose, methacrylic acid-ethyl acrylate
copolymer (1:1) dispersion 30 per cent, talc, macrogol, titanium
dioxide, polysorbate 80, colloidal anhydrous silica, mannitol,
docusate sodium, crospovidone, xanthan gum, strawberry flavour, citric
acid, magnesium stearate, E171 and E172. Each sachet provides 2.5g of
sucrose (sugar). If you are taking two or more sachets a day, ZOTON
Suspension will provide 5g or more of sucrose. Do not use if you are
known to suffer from a bowel or other condition that makes you
intolerant to certain sugars such as sucrose, fructose, glucose or
galactose. Ask your doctor if you are unsure.
ZOTON Capsules 15mg are available in packs of 28 or 56 capsules.
ZOTON Capsules 30mg are available in packs of 2, 7, 14, 28 or 56
capsules.
ZOTON Suspension 30mg is available in packs of 2 or 28 sachets.
The product licence holder of ZOTON Capsules and Suspension is
Cyanamid of Great Britain Limited, Fareham Road, Gosport, Hants, PO13,
0AS. The manufacturer of the capsules is Wyeth Medica Ireland, Little
Connell, Newbridge, County Kildare, Ireland. The manufacturer of Zoton
Suspension is Wyeth Lederle SpA., via Nettunense 90, Aprilia, Italy.
Your doctor has prescribed ZOTON, which works by reducing the amount
of acid your stomach produces. It helps to heal peptic ulcers or a
condition called reflux oesophagitis and to prevent them from
recurring. It may be used to relieve symptoms of dyspepsia such as
heartburn, stomach ache, nausea or bloating, caused by too much acid
in the stomach. ZOTON can be used to treat or prevent stomach or
duodenal ulcers while you continue to take NSAIDs. It can also provide
relief of symptoms associated with taking NSAIDs such as abdominal
pain. ZOTON may also be used with antibiotics to treat infection with
a bacterium called Helicobactor pylori. (See over to find out more
about these conditions). Please ask your doctor if you would like more
information.
Before taking your medicine
If the answer to any of the following questions is “yes”, please tell
your doctor or chemist. ZOTON may not be suitable for you.
are you pregnant or breast feeding?
do you have liver problems?
are you taking any other medicines, in particular the contraceptive
pill, phenytoin, carbamazepine, theophylline, warfarin or indigestion
mixtures?
are you allergic to any of the ingredients contained in ZOTON Capsules
or Suspension?
How to take your medicine
Always take your medicine as your doctor tells you to. Read the
chemist’s label to remind you how many sachets or capsules you should
take and how often you should take them. If you are taking one capsule
or sachet a day, you should try to take it at the same time each day.
If possible, you should take it first thing in the morning before
breakfast. You should swallow ZOTON Capsules whole with water. Do not
crush or chew them. ZOTON Suspension sachets should be emptied into a
small cup or glass containing two tablespoonfuls (30ml) of tap water,
and stirred until it has an even consistency. The mixture should be
swallowed immediately. WW 228/2 The usual adult dose for Helicobacter
pylori infection is ZOTON 30mg twice a day, one dose in the morning
and the other in the evening. ZOTON should not be used alone to treat
Helicobacter pylori infection. Your doctor will also prescribe two
antibiotics to be taken at the same time. The usual adult dose for
dyspepsia is ZOTON 30mg once a day for 2 to 4 weeks. The usual adult
dose for peptic ulcer or reflux oesophagitis is ZOTON 30mg once a day
for 4 or 8 weeks. After this time, if you are able to take capsules,
the dose may be reduced to 15mg once a day. If you are prescribed
ZOTON to treat an ulcer whilst continuing to take an NSAID, your
doctor will advise you of the correct dose depending on your symptoms.
This is usually either one dose of 15mg or one dose of 30mg a day for
4 or 8 weeks. If you are taking ZOTON to prevent an ulcer from forming
whilst you are taking an NSAID, you will usually be asked to take one
15mg dose or one 30mg dose a day. Your doctor will tell you how long
to take ZOTON for. If your stomach produces far too much acid, you
will usually be asked to take two 30mg capsules or two sachets a day
to start with. Your doctor may then increase or decrease this,
depending on your response. You will usually feel better before you
are completely healed. Therefore, it is important that you take all
the sachets or capsules that your doctor has prescribed for you. If
you forget to take a dose, take it as soon as you remember. However,
if it is almost time for your next dose, skip the missed dose and
continue taking the remaining sachets or capsules as normal. Do not
take a double dose. If you take more ZOTON than your doctor or chemist
advised, you should seek medical advice quickly.
After taking your medicine
Occasionally, ZOTON may cause side effects. Such side-effects do not
usually last for long. However, please see your doctor if any of the
following become severe or troublesome: Headaches, diarrhoea, stomach
pain, feelings of sickness, vomiting, taste disturbances, dizziness,
vertigo, confusion, blurred vision, hallucinations, feeling unwell,
constipation, wind, dry or sore mouth or throat, tiredness, burning or
prickling feeling, itching, hair thinning, muscle or joint pains,
fluid retention, swelling, depression. As with other acid-reducing
drugs, men taking lansoprazole may occasionally experience temporary
breast swelling or impotence. You should contact your doctor
immediately if you develop a rash, or reddening or blistering of the
skin. The majority of rashes are mild and self-limiting but
sensitivity to sunlight and more severe blistering rashes have
occurred rarely which may require medical treatment. You should also
see your doctor at once if you get a fever, any unexplained bruising
or bleeding, extreme fatigue, difficulty in urinating, if your skin or
whites of your eyes become more yellow than usual or if you experience
symptoms of an allergic reaction such as shortness of breath or face
swelling. As natural acid in the stomach helps to kill bacteria, the
lowering of acid by acid-reducing drugs such as ZOTON may make some
people more liable to suffer from certain stomach infections. If you
suffer from severe persistent diarrhoea and/or vomiting whilst taking
ZOTON you should consult your doctor. Other rare side effects include
kidney problems, inflammation of the liver or changes in kidney or
liver function. Please tell your doctor if you have any unwanted event
not listed above. Before you have any kind of surgery or emergency
treatment, tell the doctor in charge that you are taking ZOTON.
Storing your medicine
Keep your medicine in a safe place where children cannot see or reach
it. Keep your medicine in a dry place at room temperature (below 25°C)
in the original container. Do not put it in the fridge. If any sachets
or capsules are left at the end of your treatment, please take them
back to your chemist, who will get rid of them. Do not use this
medicine after the expiry date which is printed on your pack. This
leaflet was revised in October 2000
Other Information
Remember: This medicine is for you. Only a doctor can prescribe it for
you. Never give it to anybody else, even if their symptoms are the
same as yours. It could harm them.
*Trademark of and under Licence Agreement from Takeda Chemical
Industries Ltd., Japan.
†Trade mark
ZOTON is distributed by Wyeth Laboratories,
Huntercombe Lane South,
Taplow, Maidenhead, Berkshire SL6 0PH"
http://pharma.bmj.com/en/1/otherzotonpal.html - A commercial website
for health professionals.
2 - Enteric Asprin is an asprin with a safety coating to protect the
stomach. Side effects of aspirin may be: "Aspirin is a drug that has
some key benefits, but it can also cause some serious problems.
Aspirin has been used by the human race for many years. It was first
produced by the Bayer company.
It is has been thought that aspirin gets in the way of prostaglandin
production and causes a reduction in inflammation and pain.
Prostaglandin affects the flow of blood platelets, which are the key
in blood clotting. If plaque tears inside a coronary artery, then
clotting begins at that site. This may then cause cardiac arrest or a
myocardial infraction. In today’s day and age doctors can prescribe
medicine such as aspirin to patients that have a history of heart
disease. This can then reduce that person’s risk of a second event.
Aspirin is called an analgesic drug because it is a pain reliever.
Aspirin has many side effects that other pain relievers do not have.
Aspirin can cause gastro-intestinal discomfort if taken in large
doses. Another side effect is that is prevent blood from clotting.
Aspirin is not used in hospitals because of this reasoning. When you
are about to go into surgery your doctor will remind you not to take
aspirin 24 hours before surgery because this may cause complications
during surgery."
http://allsands.com/Health/historyofaspi_wvw_gn.htm - Aspirin Side
Effects - - There are several brands and manufacturers.
3 - Adalat LA is a trade name for Nifedipine which is a calcium
blocker. "Calcium channel blockers are used to treat high blood
pressure, angina, arrhythmias (irregular heart rhythm), Raynaud's
phenomenon (a narrowing of the blood vessels in the fingers, toes,
ears and nose) and to prevent vascular spasms in those who have had a
subarachnoid haemorrhage (bleeding into the space surrounding the
brain).
How do they work?
Calcium channel blockers reduce the flow of calcium into the heart and
smooth muscle cells (found in many tissues and organs in the body).
The body needs calcium in order for muscles to function correctly, but
decreasing the amount of calcium that reaches the muscles can help
blood vessel walls to relax and blood to flow more freely into the
heart. In turn, this can lower blood pressure and relieve angina pain.
Calcium channel blockers can also slow the electrical impulses that
pass through heart muscle and consequently can stabilise abnormal
heart rhythms.
Other drugs
If you are taking water tablets or ACE inhibitors, the hypotensive
(lowering of blood pressure) effect of calcium channel blockers can
become greater. Nifedipine can occasionally make glucose tolerance
worse if you are taking an oral hypoglycaemic tablet (taken for Type 2
diabetes). If you are also taking other anti-hypertensive (anti high
blood pressure) drugs, there can be an enhanced hypotensive effect.
Side effects
Side effects common to a majority of the calcium channel blockers are
headaches, dizziness, flushing, nausea, oedema (accumulation of fluid
in the body tissue) and palpitations."
With this drug, according to all the information I can find, you must
speak with your doctor about additional side effects and interactions.
4 - Atenolol - there is a lot of information available here. So,
rather than try to quote several pages of text, I am simply going to
send you to the Atenolol Home Page.
http://www.sunderland.ac.uk/~hs0dad/profile/atenolol/atenhmpg.htm - -
You will fine information ranging from chemical formulation to
effects. To read the general overviews which contain what you are
looking for, click on "type of drug." You will find full information
as to interactions and precautions.
5 - mirtazapine - Once again I am going to send you to a page. These
pages contain several articles covering what the drug is, does, and
many clinical reports relating to tests, success and failure. Here is
the abstract:
"Mirtazapine is a presynaptic alpha-2 antagonist that has dual action
by increasing noradrenergic and serotonergic neurotransmission. The
enhancement of serotonergic neurotransmission is specifically mediated
via 5-HT1 receptors because mirtazapine is a postsynaptic serotonergic
5-HT2 and 5-HT3 antagonist. In addition, mirtazapine has only a weak
affinity for 5-HT1 receptors and has very weak muscarinic
anticholinergic and histamine (H1) antagonist properties. As a
consequence of its unique pharmacodynamic properties, mirtazapine is
an effective, safe and well-tolerated addition to the antidepressant
armamentarium. Mirtazapine is well absorbed from the gastrointestinal
tract following oral administration, and it is extensively metabolized
in the liver to four metabolites via demethylation and hydroxylation,
followed by glucuronide conjugation. The unconjugated desmethyl
metabolite is pharmacologically less active than the parent compound.
Mirtazapine lacks auto-induction of hepatic isoenzymes. Although
mirtazapine is a substrate of P450 isoenzymes 1A2, 2D6 and 3A4, in
vitro studies show that it is not a potent inhibitor or inducer of any
of these enzymes. Mirtazapine has been evaluated in a worldwide
clinical development program involving approximately 4500 patients.
Controlled clinical trials involving almost 2800 mirtazapine-treated
patients have demonstrated the compound to be effective for the
treatment of moderate-to-serve major depression. Mirtazapine was
consistently superior to placebo, and equivalent in efficacy to the
tricyclic antidepressants amitriptyline, doxepin and clomipramine, but
with an improved tolerability profile. Mirtazapine has shown a rapid
onset of action in patients with predominantly severe depressive
illness in a comparative study against fluoxetine. Mirtazapine has a
unique tolerability profile, since the specific postsynaptic 5-HT2 and
5-HT3 receptor blockade of mirtazapine provides early antidepressant
effects without causing unwanted serotonin-related side-effects.
Transient somnolence, hyperphagia and weight gain are the most
commonly reported adverse events, which may be attributed to the
antihistaminic (H1) activity of mirtazapine at low doses. Somnolence,
the most commonly reported side-effect, appears to be less frequent at
higher dosages. Mirtazapine also demonstrates important anxiolytic and
sleep-improving effects, which may be related to its pharmacodynamic
properties. In addition, mirtazapine does not appear to be associated
with sexual dysfunction. Mirtazapine has shown no significant
cardiovascular adverse effects at multiples of 7 to 22 times the
maximum recommended dose. Mirtazapine is a unique addition to the
antidepressant armamentarium as first-line therapy in patients with
major depression and symptoms of anxiety/agitation or
anxiety/somatization or complaints of insomnia and as a useful
alternative in depressed patients who do not adequately respond to or
are intolerant of tricyclic antidepressants or serotonin-specific
reuptake inhibitors."
http://www.biopsychiatry.com/mirtazapine.html - the page name is:
"Review of the results from clinical studies on the efficacy, safety
and tolerability of mirtazapine for the treatment of patients with
major depression "
6 - Chloral Hydrate, sometimes simply called "knock out drops"
"Chloral Hydrate - Chloral Hydrate ( Noctec ) is a sedative with a
long history of use. Used as a sleeping pill, but most the time only
prescribed if the person can not take benzodiazepines.
Warnings
This drug may increase the action of anticoagulant drugs. Be very
cautious when combining this drugs.
The liver may loss the ability to remove this drug if combined with:
Ulcer drugs, Birth control pills, propranolol or disulfiram.
Check with your physician if you are taking central nervous system
depressants like antihistamines, hay fever medicines, sedatives,
narcotics, anesthetics, barbiturates or muscle relaxants.
The habit-forming potential is moderate to high.
Do not take this drug if you are pregnant.
Do not take this drug if planning to become pregnant. Do not take if
you are breast-feeding. - Since your friend is in her 60s I doubt very
much if these last two warnings apply. However, the next line will be
very important.
Do not give this drug to children or infants. If over sixty only use
drug for a brief time and with close monitoring.
Do not use if: You had negative reactions to this drug in the past or
if you have kidney or liver disease.
Inform your Doctor if: You had negative reactions to this drug in the
past. If you are taking any other prescription or nonprescription
drug. If you plan to be under anesthesia or having any surgery in the
next few months, also if you will be undergoing any medical tests. If
you have a history of drug or alcohol dependence.
Chloral Hydrate ( Symptoms or Effects )
Common: Nausea/vomiting or drowsiness.
Rare: Stomach pain, dizziness/lightheadedness, diarrhea, rash,
confusion, anxiety/restlessness, memory loss or irritability.
See physician always: Stomach pain, drowsiness,
dizziness/lightheadedness, diarrhea, rash, confusion,
anxiety/restlessness, memory loss or irritability.
See physician if severe: Nausea/vomiting.
Stop taking and see physician NOW: Rash"
http://www.psyweb.com/Drughtm/noctec.html - a commercial website
Psyweb.com
7 - Olanzapine - Once again I'm sending you to a website due to the
amount of information. You will find information on everything from
drug identification and clinical trials and results to manufacturer
information.
http://www.priory.com/focus3.htm - the website is "Focus on
Olanzapine"
8 - didronel - another trip to a website. This is a multipage article
in PDF format so you will have to download a free Acrobat Reader if
you don't already have one. The website is Proctor and gamble
Pharmaceuticals. the PDF report is mid page, just click on it and you
will find the full manufacturers report on the product.
http://www.pgpharma.com/consumer_didronel.shtml
9 - cacit - Another PDF file containing information about the drug,
its actions and interactions.
http://www.nos.org.uk/InfoSheets/CYCLICALETIDRONATE.pdf
Search - Google
Terms - I used your drug list
websites used are included in the text of the answer.
I certainly hope the above answers many of your questions and gives
you some "ammunition" with which to approach the doctor.
If I may clarify anything, please ask before you rate the answer.
Cheers
digsalot |
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