Hello poker:
Thanks for the interesting question.
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The product Uroprin, which is used to enhance male sexual performance,
contains the drug tadalafil. The FDA put out a health advisory about
products containing tadalafil just last week:
FDA Public Health Advisory: FDA Warns Consumers Against Taking the
Following Dietary Supplements-SIGRA, STAMINA Rx and STAMINA Rx for
Women, Y-Y, Spontane ES and Uroprin
URL: http://www.fda.gov/bbs/topics/ANSWERS/2003/ANS01235.html
Quote: "FDA has determined that the products actually contain the
prescription-strength drug ingredient, tadalafil. Tadalafil is the
active ingredient in Cialis, an Eli Lilly product approved in Europe
to treat male erectile dysfunction. An interaction between certain
prescription drugs containing nitrates (such as nitroglycerin) and
tadalafil may cause a drastic lowering of blood pressure. There is
real danger that this product may be taken by patients taking nitrates
since erectile dysfunction is often a common problem in people with
diabetes, hypertension (high blood pressure), hyperlipidemia (high
cholesterol), ischemic heart disease and in people who smoke."
I did some research on tadalafil (Cialis) and found the following
specification sheet
Cialis: film-coated tablets Tadalafil
URL: http://www.mauriziobossi.com/Cialis10mg.pdf
that clearly lists both the contraindications:
*********************
Do not take CIALIS:
- if you are taking any form of organic nitrate or nitric oxide donors
such as amyl nitrite. This is a group of medicines ("nitrates") used
in the treatment of angina pectoris ("chest pain"). CIALIS has been
shown to increase the effects of these drugs. If you are taking any
form of nitrate or are unsure tell your doctor.
- if you have serious heart disease or have had a recent heart attack.
- if you have had a recent stroke.
- if you have low blood pressure or uncontrolled high blood pressure.
- if you are (hypersensitive) allergic to tadalafil or any of the
other ingredients of CIALIS.
*********************
and the possible side effects:
*********************
4. POSSIBLE SIDE EFFECTS
Like all medicines, CIALIS can have side effects. These effects are
normally mild to moderate in nature.
The most common undesirable effects are headache and indigestion. Less
commonly reported side effects are back pain, muscle aches, nasal
congestion,
facial flushing and dizziness. Uncommon effects are swelling of the
eyelids, eye pain and red eyes.
If you have any of these side effects and they are troublesome,
severe, or do not go away, tell your doctor.
Allergic reactions (including skin rashes) could occur.
In rare instances it is possible that a prolonged and possibly painful
erection may occur after taking CIALIS. If you have such an erection,
which lasts continuously for more than 4 hours, you should contact a
doctor immediately.
In case of chest pain occurring during or after sexual activity you
should NOT use nitrates but you should seek immediate medical
assistance.
If you notice any side effects not mentioned in this leaflet, please
inform your doctor or pharmacist.
Heart attack, stroke, and irregular heart beats have been reported
rarely in men
taking CIALIS. Most, but not all of these men had known heart problems
before
taking this medicine. It is not possible to determine whether these
events were
directly related to CIALIS.
Effects were seen in one animal species that might indicate impairment
of fertility. Subsequent studies in man suggest that this effect is
unlikely in humans.
*********************
I suggest you read the entire sheet for complete information and
consult your doctor befoer taking any such drug.
I hope this information helps with your research.
If you need any clarification of the information I have provided,
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Thank you.
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