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Subject:
type 4 immunological reaction
Category: Miscellaneous Asked by: cynnryan-ga List Price: $15.00 |
Posted:
01 Jul 2003 19:24 PDT
Expires: 31 Jul 2003 19:24 PDT Question ID: 224102 |
why is it when one person is subjected to a type 4 immunological reaction they only develop hives, while another person goes into anaphyletic shock? |
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Subject:
Re: type 4 immunological reaction
Answered By: synarchy-ga on 04 Jul 2003 18:04 PDT Rated: |
Hello, There are four categories of immunologic reactions. These are: Type I - anaphylactic reaction - Caused by the binding of preformed IgE antibodies to the foreign antigen. The preformed antibodies are formed after the first exposure and cause the anaphlyactic reaction upon subsequent exposure. Type II - cytotoxic - Caused by IgG and IgM antibodies - this is the principle type of reaction seen in autoimmunity Type III - immune complex - Caused by aggregates of antibodies lodging in small capillary beds where neutrophils and other cytotoxic cells become activated and cause damage. Seen most commonly in nephritic syndroms in the kidney. Type IV - delayed-type hypersensitivity - Mediated by T-cells, this type of reaction is most typified by the tuberculin skin test. Antigen is bound and causes a local infiltration (hives" So, in an overall fashion, the answer to your question is that the difference between just having "hives" and having an anyphylactic reaction is the presence of preformed IgE antibodies in the person with the anaphylactic reaction. A short overview of the types of immunologic reactions (at the very bottom): http://www.uta.edu/biology/simecka/classnotes/3312/Immunology_review.htm Another short immunology review that details the roles of various immune cells in inflammation: http://www.austincc.edu/kotrla/BB%203%20Immunology.PDF A veterinary site with pictures of immune reactions: http://www.vetmed.ufl.edu/path/teach/vem5110b/hi/hi.htm Please let me know if you have further questions. synarchy Google search: type iv immunologic reaction delayed-type hypersensitivity immunology review |
cynnryan-ga rated this answer: |
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Subject:
Re: type 4 immunological reaction
From: princesskeisha-ga on 03 Jul 2003 21:24 PDT |
Hives and Anaphylactic Shock are varying degrees of allergic reactions both caused by the production of histamines in your body in response to allergens. Histamines lower your blood pressure which could result (in some people) in shock. Anaphylaxis means a severe or systemic allergic reaction, the shock is caused by the natural consequence of the histamines lowering blood pressure to a dangerous level. But please...never say "just hives", my Epipen stands ready anytime my hives start getting the size of dinner plates, my tongue swells to the point that my breathing becomes labored and my eyes swell shut. (I have hypertension so I have been fortunate that the lowering of my blood pressure due to significant histamine production has not caused me to go into shock...yet.) |
Subject:
Re: type 4 immunological reaction
From: cynnryan-ga on 04 Jul 2003 13:35 PDT |
I need to know why does one get hives while the other goes into shock. I am not following your answer. Can you please help me clarify the difference. Thanks so much.. |
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