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Q: prescription drugs ( Answered,   0 Comments )
Question  
Subject: prescription drugs
Category: Health > Men's Health
Asked by: jerry7777777-ga
List Price: $5.00
Posted: 20 Sep 2003 17:35 PDT
Expires: 20 Oct 2003 17:35 PDT
Question ID: 258682
what is a prescription drug or drugs usually prescribed for recovering alcoholics?
Answer  
Subject: Re: prescription drugs
Answered By: bobbie7-ga on 20 Sep 2003 19:19 PDT
 
Hello jerry7777777-ga,


The following drugs are available worldwide for combating alcoholism.
One of them, disulfiram, sold as Antabuse, makes people feel sick when
they drink.

The other two drugs - acamprosate, available in Europe but not the
United States, and naltrexone - are given to ward off relapses once an
alcoholic has stopped drinking.

Recent studies have shown that the drug topiramate, marketed as
Topamax usually prescribed for epileptic patients is highly effective
in helping alcohol-dependent individuals stop drinking.


 “Only two medications are currently approved for treating alcoholics
in the U.S. -- disulfiram (Antabuse) and naltrexone. Antabuse does not
reduce cravings, it merely makes a drinker feel sick if they consume
alcohol. Naltrexone has been shown to reduce cravings in alcoholics
who have already quit drinking.”

“Another medication, acamprosate has proven to be more effective than
naltrexone, but it has yet to be approved for use in the United
States, although it has been used for years in Europe. Acamprosate is
also designed to reduce cravings after the person has stopped
drinking.”

“Topiramate is the first medication that has been shown to be
effective for persons who are still drinking. Drinkers get pleasure
from alcohol when it releases the chemical dopamine in the brain,
researchers say. Topiramate works by "washing away" the excess
dopamine. In other words, alcoholics no longer get any pleasure from
drinking.”

“Researchers at The University of Texas Health Science Center at San
Antonio reported that heavy drinkers were six times more likely to
remain abstinent for a month if they took the medication, even in
small doses.”
Alcoholism: About.com
http://alcoholism.about.com/cs/meds/a/aa030517.htm



===================================================


Trade and Generic Names of Psychiatric Medications. 
Compiled by, Ivan Goldberg, MD
----------------------------------------------------------------------
Trade name              Generic name         Use of Medication
----------------------------------------------------------------------
Antabuse                     disulfiram             Rx of alcoholism
Nalorex                       naltrexone             Rx of alcoholism
ReVia                          naltrexone             Rx of alcoholism
Phaltrexia                    naltrexone             Rx of alcoholism
Trexan                         naltrexone             Rx of alcoholism
Nalorex                       naltrexone              Rx of alcoholism
-----------------------------------------------------------------------
Psycom.net
http://www.psycom.net/depression.central.drugnames.html



===================================================


From CBS News:

Topiramate

“An epilepsy drug offers significant promise in helping alcoholics
quit drinking and appears to be more effective than drugs now in use
for the problem, a new study shows.

“Researchers found that those given the medication were six times more
likely than those on a dummy pill to abstain from alcohol for a month,
according to the report published Friday in The Lancet”

CBS News: May 2003
http://www.cbsnews.com/stories/2003/05/16/health/main554339.shtml




=============
Disulfiram- Antabuse
=============

“Disuifiram produces a sensitivity to alcohol which results in a
highly unpleasant reaction when the patient under treatment ingests
even small amounts of alcohol.”
RX List 
http://www.rxlist.com/cgi/generic/disulfiram_cp.htm


“Disulfiram is an aid in the management of selected chronic alcohol
patients who want to remain in a state of enforced sobriety so that
supportive and psychotherapeutic treatment may be applied to best
advantage.”

“Disulfiram is not a cure for alcoholism. When used alone, without
proper motivation and supportive therapy, it is unlikely that it will
have any substantive effect on the drinking pattern of the chronic
alcoholic.”
RX List
http://www.rxlist.com/cgi/generic/disulfiram_ids.htm


Disulfiram at Medline Plus:

 “Disulfiram is used to treat chronic alcoholism. It causes unpleasant
effects when even small amounts of alcohol are consumed. These effects
include flushing of the face, headache, nausea, vomiting, chest pain,
weakness, blurred vision, mental confusion, sweating, choking,
breathing difficulty, and anxiety. These effects begin about 10
minutes after alcohol enters the body and last for 1 hour or more.
Disulfiram is not a cure for alcoholism, but discourages drinking.”

Medline Plus
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682602.html



==========
Naltrexone
==========

“Naltrexone is used to help people who have a narcotic or alcohol
addiction stay drug free. Naltrexone is used after the patient has
stopped taking drugs or alcohol. It works by blocking the effects of
narcotics or by decreasing the craving for alcohol.”

“Naltrexone helps decrease the craving for narcotics or alcohol but
does not treat addiction. It is important that you attend all
counseling, support group meetings, and other treatments prescribed by
your doctor. Take naltrexone regularly. Do not stop taking it without
talking to your doctor.”

Medline Plus
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a685041.html



==================
Naltrexone - Revia
==================

REVIA is indicated: “In the treatment of alcohol dependence and for
the blockade of the effects of exogenously administered opioids.”

“REVIA has not been shown to provide any therapeutic benefit except as
part of an appropriate plan of management for the addictions.”

Source: RX List 
http://www.rxlist.com/cgi/generic2/naltrexone_ids.htm


You may read more about Naltrexone for Alcoholism from Your Family
Doctor:
http://familydoctor.org/handouts/130.html



Search Criteria:

Medications alcoholism
Antabuse
Revia
Naltrexone
Topiramate

Please note that answers and comments provided on Google Answers
are general information, and are not intended to substitute 
informed professional medical advice.

If anything is unclear or if a link does not function, please let me
know and I’ll be glad to offer further assistance.


Best Regards,
Bobbie7-ga

Clarification of Answer by bobbie7-ga on 20 Sep 2003 19:29 PDT
Additional information that may interest you:

Drug Therapy of Alcoholism
   
“When other disorders besides alcoholism(depression, bipolar disorder,
anxiety, schizophrenia &etc.) are present along with alcoholism,
appropriate drug treatment of these conditions is necessary lest they
interfere with the recovery from alcoholism. However, successful
treatment of such associated("dual diagnosis") psychiatric conditions
does not itself directly affect the alcoholism, which is a separate
medical condition usually requiring separate medical treatment.”
Behavioral Medicine Associates
http://www.bma-wellness.com/papers/Pharmacotherapy_Alcoholism.html


Medications Can Aid Recovery from Alcoholism
by Paula Kurtzweil
Source: FDA
http://www.fda.gov/fdac/features/496_alco.html


Pharmacotherapy of Alcoholism
Charles P. O’Brien, Margaret R. Rukstalis, and Michael F. Stromberg
http://www.acnp.org/G4/GN401000169/CH.html


New Compounds in the Treatment of Alcoholism
by Arline Kaplan 
Psychiatric Times  May 2000  Vol. XVII  Issue 5 
http://www.psychiatrictimes.com/p000568.html


Evidence Report/Technology Assessment: Number 3
Pharmacotherapy for Alcohol Dependence
The Agency for Health Care Policy and Research
http://www.ahcpr.gov/clinic/epcsums/alcosumm.htm


Researchers Identify Potential Medication
for Early-Onset Alcoholism
News Release from NIAAA
http://alcoholism.about.com/library/blnaanews000822.htm?once=true&terms=acamprosate


Disulfiram 
Brand name: Antabuse  
Drug monograph
http://www.mentalhealth.com/drug/p30-a02.html
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