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| Subject:
control of striated muscle
Category: Science > Biology Asked by: jkhansard-ga List Price: $2.00 |
Posted:
28 Sep 2003 00:07 PDT
Expires: 27 Oct 2003 23:07 PST Question ID: 260901 |
what would happen if you bathed the inside of the muscle fiber with EGTA? |
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| Subject:
Re: control of striated muscle
Answered By: synarchy-ga on 29 Sep 2003 18:41 PDT |
Hello - Calcium is necessary for the contraction of muscle - EGTA is a chelator (compound which binds to metals) that effectively "depletes" the calcium. If EGTA is put into a muscle cell, it will "sop up" the calcium, producing a decrease in contractile force and muscle relaxation. One nice page: http://www.biosci.ohio-state.edu/~patches/eeob410/muscle.html A longer description: http://www.uic.edu/classes/phyb/phyb516/regulationmusclecontru3.htm A historical account of the investigations that led to our understanding of the role of calcium in muscle contraction (used EGTA): http://www.actabp.pl/pdf/3_2000/493-516s.pdf synarchy Search terms EGTA muscle contraction |
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