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Subject:
Energy drink helps chemotherapy patients - CARNITENE
Category: Health > Medicine Asked by: bdpots-ga List Price: $20.00 |
Posted:
15 Jun 2002 03:56 PDT
Expires: 22 Jun 2002 03:56 PDT Question ID: 27087 |
A Pinapple flavoured drink is helping to reduce fatigue according to an Italian (unknown)scientist. It contains a substance called levocarnitene, which is converted in the body to an amino acid calledcarnitene,vital for delivering energy to muscles. Any information on use and availability would be helpful ( in the UK ) |
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Subject:
Re: Energy drink helps chemotherapy patients - CARNITENE
Answered By: fons-ga on 15 Jun 2002 04:44 PDT |
Hi bdpots-ga, Thanks for your question. Let's first try to get the spelling right. According to the sources I have seen we talk about carnitine and levocarnitine, also called l-carnitine. It is used as a rather generic medicine and if you are interested in the medical information, you can check it at medlineplus. Your question is really very timely, as the Italian research was only recently published in the British Journal of Cancer, and media published about it about one week ago. I could not yet retrieve the original article at the web site of the British Journal of Cancer, but it might be coming online later. It can be administered in several ways, and in some countries it might even bee included in the medical health system. As a drink it is really popular for sport and some websites claim it can reduce your fat. You can get it in any possible taste. I have included a few websites for buying health products online, including carnitine containing tablets and drinks (although you would have to mix it probably yourself with pineapple in the last case - but then delivery in the UK is for free). If I were you, I would go to the nearest trendy sport school. After all the newsstories, they will have it on the shelves. Regards, Fons For medical information, go to http://www.nlm.nih.gov/medlineplus/druginfo/levocarnitinesystemic202325.html Two sites promoting the usage of drinks containing levocarnitine: http://www.marylandmenus.com/surfcity.htm http://www.jpscoffee.com/f&b_menu1.htm Find here a media-report on the findings. I had to use a cache at the google-site, please scroll to June 11: http://216.239.33.100/search?q=cache:erO8zVEmgUYC:www.msnbc.com/news/459645.asp%3F0si%3D-+levocarnitine+pineapple+UK&hl=en&ie=UTF8 Or a Reuters dispatch at http://www.spectrum.ieee.org/htmlCache/ And the site of the British Journal of Cancer: http://www.nature.com/bjc/ For your online shopping: http://www.completenutrition.co.uk/Products.html http://www.worldwideshoppingmall.co.uk/body-soul/product.asp?productref=DL-AB-0 Search strategy: Google: carnitine+pineapple(+UK) |
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Subject:
Re: Energy drink helps chemotherapy patients - CARNITENE
From: mydogrex-ga on 10 Jul 2002 10:55 PDT |
Abstract of BJC article from Pubmed: Br J Cancer 2002 Jun 17;86(12):1854-7 Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. Graziano F, Bisonni R, Catalano V, Silva R, Rovidati S, Mencarini E, Ferraro B, Canestrari F, Baldelli AM, De Gaetano A, Giordani P, Testa E, Lai V. Medical Oncology Unit, Hospital of Urbino, Via Bonconte da Montefeltro, 61029 Urbino, Italy. frada@tin.it Ifosfamide and cisplatin cause urinary loss of carnitine, which is a fundamental molecule for energy production in mammalian cells. We investigated whether restoration of the carnitine pool might improve chemotherapy-induced fatigue in non-anaemic cancer patients. Consecutive patients with low plasma carnitine levels who experienced fatigue during chemotherapy were considered eligible for study entry. Patients were excluded if they had anaemia or other conditions thought to be causing asthenia. Fatigue was assessed by the Functional Assessment of Cancer Therapy-Fatigue quality of life questionnaire. Treatment consisted of oral levocarnitine 4 g daily, for 7 days. Fifty patients were enrolled; chemotherapy was cisplatin-based in 44 patients and ifosfamide-based in six patients. In the whole group, baseline mean Functional Assessment of Cancer Therapy-Fatigue score was 19.7 (+/-6.4; standard deviation) and the mean plasma carnitine value was 20.9 microM (+/-6.8; standard deviation). After 1 week, fatigue ameliorated in 45 patients and the mean Functional Assessment of Cancer Therapy-Fatigue score was 34.9 (+/-5.4; standard deviation) (P<.001). All patients achieved normal plasma carnitine levels. Patients maintained the improved Functional Assessment of Cancer Therapy-Fatigue score until the next cycle of chemotherapy. In selected patients, levocarnitine supplementation may be effective in alleviating chemotherapy-induced fatigue. This compound deserves further investigations in a randomised, placebo-controlled study. Copyright 2002 Cancer Research UK Stores that sell carnitine in the UK. www.dnavitamins.co.uk/ www.weightlossstore.co.uk/thermoserum.htm |
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