Although a search at DrugDigest's Drug Interactions  indicated no
interactions, according to drug interaction notices at MedlinePlus,
it's absolutely *imperative* that both your cardiologist *and* your
nephrologist know what the other has prescribed.
 Drug Interactions, searched on acetazolamide (ACTZ) and Lisinopril
ACTZ (acetazolamide) is prescribed to treat a number of conditions,
including glaucoma, altitude sickness, and epilepsy. When presecribed
by a nephrologist, it is intended as a diuretic (water pill). This in
and of itself doesn't appear to pose a problem, except in certain
"Although certain medicines should not be used together at all, in
other cases two different medicines may be used together even if an
interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are
using carbonic anhydrase inhibitors, it is especially important that
your health care professional know if you are using any of the
* Amphetamines or
* Mecamylamine (e.g., Inversine) or
* Quinidine (e.g., Quinidex)?Use of carbonic anhydrase inhibitors
may increase the chance of side effects
* Methenamine (e.g., Mandelamine)?Use of carbonic anhydrase
inhibitors may decrease the effectiveness of methenamine"
Lisinopril, an anti-hypertensive (used to lower blood pressure),
carries this caution:
"This medicine has been tested in a limited number of patients 65
years of age or older and has not been shown to cause different side
effects or problems in older people than it does in younger adults.
Other medicines?Although certain medicines should not be used together
at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may
want to change the dose, or other precautions may be necessary. When
you are taking or receiving ACE inhibitors it is especially important
that your health care professional know if you are taking any of the
* Alcohol or
* Diuretics (water pills)?Effects on blood pressure may be
increased. In addition, some diuretics make the increase in potassium
in the blood caused by ACE inhibitors even greater
* Potassium-containing medicines or supplements or
* Salt substitutes or
* Low-salt milk?Use of these substances with ACE inhibitors may
result in an unusually high potassium level in the blood, which can
lead to heart rhythm and other problems"
Acetazolamide and Lisinopril in combination *may* affect your blood
pressure, so be certain to consult with both of your doctors to ensure
that your dosage is appropriate.
I hope you find this information helpful. If I can be of further
assistance, please just ask for clarification. I'll be glad to help.
Search terms: [ acetazolamide ] and [ lisinopril ] at MedlinePlus