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Q: Detecting platelet storage pool disorder (SPD) in rats ( No Answer,   0 Comments )
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Subject: Detecting platelet storage pool disorder (SPD) in rats
Category: Science > Biology
Asked by: tianakaesha-ga
List Price: $15.00
Posted: 07 Jan 2004 19:21 PST
Expires: 29 Jan 2004 20:04 PST
Question ID: 294258
Thankyou for taking the time to look at my questions.

Through completing my own research I have found information to a
disease called (platelet) Storage Pool Disorder, otherwise known as
SPD.  In the medical research I have looked at, the testing models
were usually Fawn-Hooded rats, occasionally crossed with Wistar or
Norwegian Rats.

Firstly I was wondering if there is any pages that explain this
disorder in laymans terms. (medical pages can be a little confusing!)
I am assuming this disorder, after being referred to as a bleeder,
means that the clotting ability of the subject is slim.

Secondly, I am wondering if there is a specific test (other than blood
flow Answer all three questions (even just post a link or
two!)monitoring after a cut in the skin) similar a blood test like
they have for von Willebrands Disease.

Links:

This site has the most relevant information that I can find:
http://www.ncbi.nlm.nih.gov

Detection of SPD through timing blood flow
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7833250&dopt=Abstract

This has a lot of information about many bleeding disorders - especially in animals
http://www.med.unc.edu/wrkunits/3ctrpgm/thromb/sponher.htm

Clarification of Question by tianakaesha-ga on 08 Jan 2004 15:21 PST
Oooops! Just noticed that there was a problem with my second question.
I did spell check, honest!

What I meant to say was this:

I am wondering if there is a specific test (other than timing how long
it takes for a controlled injury to clot) that is like the von
Willebrands Disease test. eg: Testing the platlet count or protein or
something specific in the blood.

Sorry about my poor wording!
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