Dear Inisfree,
Below you will find the results of my research regarding stem cell
therapy for the regeneration of the heart for patients who have
suffered heart attacks. Full contact information is provided for each
specialist.
Several clinicians in Germany, including heart surgeon Gustav
Steinhoff, from the University of Rostock, and Andreas Zeiher, from
the University of Frankfurt, have started treating patients who have
suffered heart attacks with adult stem cells.
BioMed Central: September 2003
http://www.biomedcentral.com/news/20030926/05
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Prof. Dr. Gustav Steinhoff
--------------------------
A Medscape article discussing the application of stem cell therapy in
the treatment of cardiac damage by Dr. G. Steinhoff of the University
of Rostock, Germany.
http://216.239.37.104/search?q=cache:MW_2U8q9qnkJ:www.medscape.com/viewarticle/457173_4+%22Stem+cell+therapy%22++clinical+trial+myocardial&hl=es&ie=UTF-8
Two Stem Cell Studies Show Heart Tissue Regeneration Following Infarcts
Lancet: 01/02/2003
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256CA2005BFAC3
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Contact Information
-------------------
Prof. Dr. Gustav Steinhoff
Universität Rostock
Klinik und Poliklinik für Herzchirurgie
Schillingallee 35,
18057 Rostock,
Germanye
Mail: gustav.steinhoff@med.uni-rostock.de
Telefone: (0381) 494 6101
Fax: (0381) 494 6102
http://www.herzchirurgie-rostock.de/impressum.html
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Prof. Dr. Andreas Zeiher
------------------------
Stem Cell Therapy Helps Heal Damaged Heart
Andreas M. Zeiher, M.D., chairman, department of medicine, University
of Frankfurt, Germany
?Infusing a patient's own stem cells into a heart artery several days
after a heart attack improves the heart's pumping power and speeds the
healing process, German cardiologists report.?
?The study included only 28 patients, and the journal report covers
just the first four months of treatment. But encouraging longer-term
results have prompted the start of a larger trial, says study author
Dr. Andreas M. Zeiher, chairman of the University of Frankfurt
department of medicine.?
Healthfinder.gov: Oct. 14, 2003
http://www.healthfinder.gov/news/newsstory.asp?docID=515502
?Dr. Andreas Zeiher?s group demonstrated that hematopoietic stem cells
?primed? to become endothelial cells though a brief treatment with
VEGF, are incorporated into new vessels. Using murine infarct models,
Dr. Zeiher?s group demonstrated that ?stem cells? primed with VEGF
localize to the infarcted area. Next, Dr. Zeiher showed the results of
a small trial in which circulating progenitor cells were injected in
patients with acute myocardial infarction, together with standard
therapy, including primary angioplasty. The group of patients treated
with stem-cells showed an improvement of cardiac function, assessed by
LV angiography, echocardiography, FDG-PET as compared to patients
receiving the conventional treatment only. The effect was more
remarkable in patients with larger myocardial infarction. The infusion
of stem cells is safe, since there were no major complications in the
treated group. This treatment has also been applied to patients with
ischemic heart failure. Initial data are promising also for this type
of patients.?
ESC Congress Vienna: 2003
http://www.escardio.org/newscasts/2003/mon_01_sept/candolleri.htm
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Contact Information
-------------------
Prof. Dr. Andreas Zeiher
Zentrum der Inneren Medizin
Frankfurt
Telefone: +49(69)6301-5789
Fax: +49(69)6301-6374
E-Mail: zeiher@em.uni-frankfurt.de
http://www.witrans.uni-frankfurt.de/forschungsbericht/f21/i82/p323/prof.htm
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Prof. Dr. med. Bodo-Eckehard Strauer
--------------------------------------
Dusseldorf, Germany: Professor Dr Bodo E. Strauer principal
investigator in the study of stem-cell infusion after heart attacks.
?Dr. Bodo Strauer of Heinrich Heine University in Dusseldorf and
colleagues tested 40 heart attack patients ? half of whom got bone
marrow cells. (..) They found that the patients given stem cells
seemed to regenerate new heart tissue. The damaged area shrank, and
the heart?s pumping ability improved.?
MSNBC: Nov 2003
http://msnbc.msn.com/id/3475861/
?Twenty patients at Heinrich Heine University who agreed to receive a
bone-marrow stem-cell infusion after heart attack showed improvement
in heart pumping strength three months later. Twenty patients who
refused the treatment had no improvement. The stem cell patients also
had a much smaller area of damage after three months than before the
treatment, said principal investigator Bodo E. Strauer, M.D.?
InteliHealth News Service: November 11, 2003
http://www.intelihealth.com/IH/ihtIH/WSIHW000/24479/33000/371828.html
The Clinic for Cardiology, Pneumology and Angiology of the Düsseldorf
Heinrich Heine University has been recognized both on a national and
an international level as one of the main centers for treating cardiac
and circulatory diseases.
Key treatment areas: Stem-cell transplantation after myocardial infarct
Key research areas: Coronary heart disease including stem-cell therapy
http://www.uniklinik-duesseldorf.de/ukd/englisch/About+UKD/Clinics/Clinic+for+Cardiology%2C+Pneumology+and+Angiology/index_1.html
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Contact Information
-------------------
Professor Dr Bodo E. Strauer
Clinic for Cardiology, Pneumology and Angiology
Department of Medicine
Division of Cardiology
Heinrich-Heine-University
Moorenstrasse 5
40225 Düsseldorf
Germany
Tel.: +49 (0) 2 11-8 11 88 01
Fax: +49 (0) 2 11-8 11 88 12
E-Mail: strauer@med.uni-duesseldorf.de
http://www.uniklinik-duesseldorf.de/ukd/deutsch/Unternehmen/Kliniken/Klinik%20f%FCr%20Kardiologie,%20Pneumologie%20und%20Angiologie/Team%20__%20Kontakt/index_1.html
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Prof. Dr. Med. Helmut Drexler
-----------------------------
According to Helmut Drexler, M.D., chief of cardiovascular medicine at
the University of Hannover:
?There is now the possibility or potential that stem cells from the
bone marrow might [change] into heart muscle and we might enter into a
new era and not only preserve heart muscle but also regenerate it."
?In Dr. Drexler's study, 60 patients were randomly assigned to receive
bone-marrow stem cells or no cells four days after they survived a
heart attack and had balloon angioplasty to open clogged arteries.
Cells were removed from the hip and transferred to the reopened artery
through a thin tube called a catheter. Heart function was measured
before the procedure and six months later by doctors who did not know
who got the cell transplants, Dr. Drexler said. They found pumping
ability had improved nearly 7 percent in those who received the cells
and less than 1 percent in the other group, he said.?
InteliHealth News Service: November 11, 2003
http://www.intelihealth.com/IH/ihtIH/WSIHW000/24479/33000/371828.html
Rebuilding the Heart: Marrow cells boost cardiac recovery
http://www.sciencenews.org/20031122/fob1.asp
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Contact Information
-------------------
Prof. Dr. Helmut Drexler
Department of Cardiology and Angiology
Hannover Medical School
Carl-Neuberg-Strasse 1
30625 Hannover
Germany
Tel. 0511 - 532 -3840/3841
Fax: 0511 - 532 - 5412
Email: Drexler.Helmut@MH-Hannover.de
http://www.mh-hannover.de/kliniken/kardiologie/html/mitarbeiter.html
Secretary:
Frau Dagmar Jenke
Email: Jenke.Dagmar@mh-hannover.de
http://www.mh-hannover.de/kliniken/kardiologie/html/patinfo.html#kontakt
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Dr. Emerson Perin, M.D., Ph.D.
------------------------------
?Doctors at Pro-Cardiaco Hospital in Rio de Janeiro offered a
fast-failing Aguia an opportunity to become the first of 21 patients
enrolled in what is believed to be the largest cardiovascular stem
cell study in the world.?
?Conducted collaboratively between Houston's Texas Heart Institute and
Pro-Cardiaco Hospital, Houston doctors have been making frequent trips
to Brazil since December 2001, when the study began, to treat damaged
human hearts with stem cells taken from the patients' own bone marrow.
When implanted in the heart, would these stem cells, doctors wondered,
help strengthen damaged heart muscle??
?A year later, they had their answer. Patients not only improved, but
they wildly improved, surpassing all expectations. These people are
reborn. The stem cell injections 'woke up' their hearts," says Emerson
Perin, M.D., Ph.D., director of New Interventional Cardiovascular
Technology at the Texas Heart Institute. Perin, a native Brazilian who
maintains close clinical and research ties with Pro-Cardiaco Hospital,
performed the stem cell implantations in Brazil.?
?The Food and Drug Administration may soon agree. Currently, the
agency is negotiating with Perin and other key Texas Heart Institute
and St. Luke's Episcopal Hospital players on the final details for a
similar study to be held in Houston. If approved, the study could
begin as soon as this summer.?
Texas Heart Institute: June 2003
http://www.texasheartinstitute.org/stemart1.html
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Contact Information
-------------------
Emerson C. Perin, MD, F.A.C.C.
Texas Heart Institute
Director, New Cardiovascular Interventional Technology, THI
6624 Fannin, Suite 2220,
Houston, TX 77030
713-791-9400
FAX 713-795-5651
e-mail: eperin@crescentb.net
http://www.texasheartinstitute.org/adult_3.html
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Christopher A. Glover
---------------------
Here is another alternative: Stem-cell drug
?Canadian researchers have found that a drug that stimulates the
production of stem cells in adults holds promise for patients who have
suffered serious heart attacks.?
?Doctors are so encouraged by the results that they will launch a
larger study to determine whether the drug helps hearts grow new cells
to replace damaged tissue.?
?The drug -- granulocyte colony stimulating factor, or G-CSF -- was
tested in only five heart-attack patients, says Chris Glover, a
researcher at the University of Ottawa and the Ottawa Heart Institute.
A clinical trial will begin this spring involving up to 85 to 100
patients?
The Globe and Mail: November 2003
http://www.globeandmail.com/servlet/ArticleNews/TPStory/LAC/20031112/UDRUG12/TPHealth/
?A drug that stimulates bone marrow to produce stem cells helped
regenerate damaged heart muscle in one of the first studies of its
kind, according to a report presented at the American Heart
Association's Scientific Sessions 2003.?
"Research has shown that there are cells in the heart that come from
bone marrow stem cells. We hypothesized increasing these cells after a
heart attack may help the heart regenerate heart muscle cells, and
this is supported by our results," said Glover, assistant professor of
medicine at the University of Ottawa and the Ottawa Heart Institute in
Ontario.?
http://www.globaltechnoscan.com/19thNov-25thNov03/stem_cells.htm
Anormed Announces Initiation Of A New Clinical Program In Heart Attack Patients
?An increasing number of publications have shown that treatment with
stem cells helps repair heart tissue and improves heart function in
patients who have suffered a heart attack. At the 2003 American Heart
Association (AHA) conference last week, a group from the Ottawa Heart
Institute reported that increasing the number of stem cells in
circulation in heart attack patients, after a heart attack, led to
improvements in heart function.1 AnorMED?s preclinical data, also
reported at 2003 AHA Conference, shows that AMD3100 improves heart
tissue and function when administered following a heart attack.2
Combined, these results support further evaluation of AMD3100 as a
potential stem cell agent to help repair damaged heart tissue in
patients who have had a heart attack. The Company plans to initiate
this clinical program in 2004.?
Anormed Press Release: November 2003
http://www.anormed.com/news/details.cfm?release_number=103
-------------------
Contact Information
-------------------
Christopher A. Glover
University of Ottawa Heart Institute
40, rue Ruskin
Ottawa, ON K1Y 4W7
Canada
Telephone +1 613 761-4742
Fax: + 1 613 761-5281
Email: cardiology@ottawaheart.ca
Email:research@ottawaheart.ca
AnorMED Inc.
#200 - 20353 64th Avenue
Langley, British Columbia
Canada V2Y 1N5
Email: info@anormed.com
T: 604.530.1057
F: 604.530.0976
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Dean J. Kereiakes, MD
--------------------------
Cincinnati Surgeons First in U.S. to Perform Stem Cell Transplantation
to Re-grow Heart Muscle
Contact :Erika Turan (513) 585-7200
?On June 5, cardiothoracic surgeons with Ohio Heart Health Center were
the first in the nation to perform stem cell transplantation on a
heart failure patient during coronary artery bypass surgery at The
Christ Hospital in Cincinnati, OH. The procedure is part of a national
clinical trial that tests the safety and efficacy of injecting a
patient's own muscular stem cells into damaged heart muscle in an
attempt to re-grow new functional heart muscle. In Cincinnati, the
trial is being coordinated by The Lindner Clinical Trial Center.?
Dean J. Kereiakes, M.D., medical director of the Lindner Center and a
lead investigator in the study.
The Health Alliance http://www.besthearthealth.com/newsflash.nsf/0/ee24709aae44096985256d3d003eac9c?OpenDocument
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Contact Information
-------------------
Dean J. Kereiakes, MD
The Ohio Heart Health Center
Mt. Auburn Office
2123 Auburn Ave., Ste 139
Cincinnati, OH 45219
513-721-8881
http://www.besthearthealth.com/heart.nsf/webview/kereiakes_dean_j
Correspondence to Dean J. Kereiakes, MD,
The Lindner Center for Research & Education,
2123 Auburn Ave, Suite 424,
Cincinnati, OH 45219.
E-mail lindner@fuse.net
http://circ.ahajournals.org/cgi/content/abstract/108/11/1310
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Search Criteria:
?Stem cell? ?heart attack?
?Stem cell therapy? regeneration heart
?Myocardial infarction? ?stem cell?
?Stem Cell Therapy? ?Cardiac Regeneration?
I hope this information is helpful.
Best regards,
Bobbie7
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