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Subject:
Shingles, Postherpetic neuralgia and Nerve Blocks
Category: Health Asked by: crohnietoo-ga List Price: $5.00 |
Posted:
21 Feb 2004 14:20 PST
Expires: 22 Mar 2004 14:20 PST Question ID: 309286 |
I'm a 61 year old female on the immuno suppressant Imuran for Crohn's disease and doing very well. In symptomatic remission and all blood work has been good. I recently developed a case of shingles after a week of severe aching pain at the waistline, sometimes in the left flank, other times at the left lower rib in back. One ER trip and morphine IV plus phenergan for the morphine induced vomiting with an inconclusive Dx of constipation, Crohn's, a 6cm ovarian cyst we've been watching for a year pushing on a nerve or muscle. A second trip to ER two days later and more IV morphine before the rash began to appear and a shingles Dx. Immediately started on Valtrex 500 mg 2 x daily, Elavil 10 mg 1 x daily, Neurontin tapering up to 300 mg 3 x daily, Hydrocodone/APAP 7.5/750 to be taken 1-2 tabs every 3-4 hours. Nerve blocks have been suggested to prevent or reduce the 50% or greater chance of postherpetic neuralgia. I am terrified of sedation and not knowing what they are doing. I'm even more terrified of a needle anywhere near my spine. My rash is considerably milder than the horrible pictures I've seen on the net. Its an intermittent series of rash from the left of my spine to the left of my belly button. The burning or itching has pretty much been non-existent, at least not real troublesome. An OTC 1% Menthol/1% Pryamoxine hydrochloride cream is treating it very well and since the rash erupted on Valentine's day has made the rash more and more pale with only a few still angry red spots and no blistering or scabbing. It seems that nerve blocks to lessen or prevent the occurance of PHN are somewhat controversial or at least the results inconclusive with no current research into their use to lessen or prevent the occurence of PHN. I would feel much better about deciding whether to undergo these "preventive" nerve blocks if I could see a detailed video of one actually being done. My fear of sedation and anesthesia is not not waking up but rather not knowing what they are doing and having no say in what they are doing. But my fear of a needle in or near my spine is even greater. Just numbing my back wouldn't work. The minute someone went behind me or I even felt the gauze alcohol swab on my back they would have to peel me off the ceiling if I was even in the same room at the time! More likely I'd be out the door! Is the sedative given via IV? How do they determine which nerve(s) to block? Does the needle go in the spinal cord/column or into the nerve outside of and next to the spine? Is there a detailed, explicit video of the procedure available that I could view before deciding? Can you get spinal headaches from a nerve block? What are the risks? Given the simplicity of my rash as compared to pictures on the web could that be any indication of less likelihood of my getting PHN? Is the pain I experienced prior to onset of the rash any indication of greater chances of developing PHN? What other questions should I be asking? I've been told that the nerve block(s) should be done before the rash is totally gone for best results in preventing PHN. I have done preliminary searches at PubMed and google using "shingles" "postherpetic neuralgia" and "nerve block". |
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There is no answer at this time. |
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Subject:
Re: Shingles, Postherpetic neuralgia and Nerve Blocks
From: hirobusa-ga on 13 Mar 2004 15:17 PST |
Is the sedative given via IV? It would depend on the practitioner, but probably IV for a quicker effect more dependably and on time. How do they determine which nerve(s) to block? The rash or the pain will be in a distibution consistent with 1-3 dermatomes, or bands- the nerves wrap around your tummy from the backlike a band of sticky tape each corresponding to a spinal level. I presume they would try to do the procedure in the dermatome in the middle because strictly speaking the problem is just in one dermatome or band. I don't know much about nerve bocks so the question is what are they proposing to do? Some attempt to block the actual sensory dorsal root or a "Sympathetic" block blocking the sympathetic nerve plexus or simply an epidural which may modulate root pain????????? An Epidural is the most likely. Does the needle go in the spinal cord/column or into the nerve outside of and next to the spine? Don't know what they are proposing but you can take it that it will be outside of the spinal canal. Is there a detailed, explicit video of the procedure available that I could view before deciding? Sorry, Don't know Can you get spinal headaches from a nerve block? If they enter the spinal canal inadvertantly... What are the risks? At a GUESS: Infection, Bleed, Pain and Discomfort, (All highly unlikely), Procedure failure, Requirement for repeat, Weakness and numbess in other levels Given the simplicity of my rash as compared to pictures on the web could that be any indication of less likelihood of my getting PHN? I don't think it does. But a better indicator may be the absence of burning pain at this stage. Is the pain I experienced prior to onset of the rash any indication of greater chances of developing PHN? I don't think so, _____________________________________ You could look at www.emedicine.com http://www.emedicine.com/med/topic2361.htm for basic VZV information Follow this link which explains the rationale of these treatments which appear to be epidural attempts, in which case they may have the adverse effect of tracking down the epidural space and therefore leaving you a little numb/weak for a while http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=15005813 These are the combined results for a PHN AND in PUBMed 1: Mizuno J, Sugimoto S, Ikeda M, Kamakura T, Machida K, Kusume S. [Treatment with stellate ganglion block, continuous epidural block and ulnar nerve block of a patient with postherpetic neuralgia who developed complex regional pain syndrome (CRPS)] Masui. 2001 May;50(5):548-51. Japanese. PMID: 11424478 [PubMed - indexed for MEDLINE] 2: Wu CL, Marsh A, Dworkin RH. The role of sympathetic nerve blocks in herpes zoster and postherpetic neuralgia. Pain. 2000 Aug;87(2):121-9. Review. PMID: 10924805 [PubMed - indexed for MEDLINE] 3: Boas RA. Sympathetic nerve blocks: in search of a role. Reg Anesth Pain Med. 1998 May-Jun;23(3):292-305. Review. PMID: 9613543 [PubMed - indexed for MEDLINE] If you use the term PHN you will find more in Pubmed than by using Post herpetic Neuralgia ____________________________________ You need to find a good Anaethesiologist and ask their opinion. You need to bare in mind that this is a treatment for which there is no good evidence and which is operator dependant. However as a recent BMJ article suggested, you don't need the proof of an evidence base to use a Parachute.... :) Write your questions down, they won't mind. |
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