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Q: Safety of Metabo-Speed XXX ( Answered,   0 Comments )
Question  
Subject: Safety of Metabo-Speed XXX
Category: Health
Asked by: sasa20-ga
List Price: $5.00
Posted: 23 Mar 2004 20:31 PST
Expires: 22 Apr 2004 21:31 PDT
Question ID: 319863
I have had my thyroid removed and am currently on Thyroxine l50 mgs.
per day.  I also have Artero-sclerosis.  Is it safe for me to take
Metabo-Speed XXX?
Thanks
Answer  
Subject: Re: Safety of Metabo-Speed XXX
Answered By: pinkfreud-ga on 23 Mar 2004 21:14 PST
 
The active ingredients of Metabo-Speed XXX are dicalcium phosphate,
bitter orange, and guarana.

This warning appears on a website that is selling the product:

"Do not use if you are pregnant or nursing or at risk of or being
treated for high blood pressure, heart disease, renal disease,
hyperthyroidism, spasms, psychiatric disease, suffer from migraines,
are allergic to tyramine or chocolate, have asthma, or are taking
asthma medication."

Rock Bottom Rx: Metabo-Speed XXX
https://www.rockbottomrx.com/products.asp?id=112

In case you are curious about the ingredients, these links will tell
you more about what's in Metabo-Speed XXX:

Pharmacy Health: Dicalcium phosphate
http://www.pharmacyhealth.net/d/dicalcium-phosphate-3201.htm

Vitacost: Bitter Orange
http://www.vitacost.com/science/hn/Herb/Bitter_Orange.htm

Pharmacy Health: Guarana
http://www.pharmacyhealth.net/d/guarana-4294.htm

More about bitter orange:

"The market is full of ?ephedra-free? products that claim to be safer.
The products claim to have 'safer' ingredients such as bitter orange
and guarana. The question everyone needs to ask now is 'Are these
herbals any safer than ephedra?' Many of these products might still
have the same dangerous side effects. Just like ephedra, they could
increase your blood pressure and heart rate.

One of the most common herbals that works like ephedra is bitter
orange (also called the Seville orange). Bitter orange is used as a
flavoring agent in such products as orange marmalade, orange candies
and orange liqueurs. The amount in these products is normally not high
enough to be harmful. However, it is also used in many energy drinks
and diet pills. These products might contain enough bitter orange to
cause serious side effects. Bitter orange could be harmful to some
people for two reasons.

Bitter orange contains synephrine, which has some of the same side
effects as ephedra. Bitter orange may interact with some medicines and
cause dangerous side effects. There is an enzyme in bitter orange that
causes this interaction."

Consumer Health: With Ephedra Gone - Are Other Diet Aids Safe?
http://www.consumer-health.com/services/cons_take39.htm

"Other substitutes for ephedra, such as green tea extract, bitter
orange and guarana, which delivers a powerful bolt of caffeine that is
two to three times as much as coffee, are already on the market.
Bitter orange contains synephrine, a chemical that gives effects
similar to ephedra when combined with caffeine, but some scientists
think it could be more harmful than ephedra."

Carolina Reporter: Upcoming ban has made ephedra scarce across Columbia
http://carolinareporter.sc.edu/archive2-25-04/25ephedra.html

"Bitter orange is not safe when used in high doses. Bitter orange,
which contains synephrine and N-methyltyramine, can cause hypertension
and cardiovascular toxicity. The adverse side effects of bitter orange
can be exacerbated when used in combination with other stimulants such
as caffeine, coffee, cola nut, ephedra, guarana, and mate."

US Army Center for Health Promotion and Preventive Medicine: Bitter Orange
http://chppm-www.apgea.army.mil/dhpw/Wellness/dietary/Factsheets/BitterOrange.pdf

"Bitter orange, or Citrus aurantium, is emerging as the central
ingredient in a new generation of herbal weight-loss products...
Gurley [Bill Gurley, professor of pharmaceutical sciences at the
University of Arkansas] said, the herbs guarana and green tea have the
potential to exacerbate the activity of Citrus aurantium].

Another potential problem with Citrus aurantium is that it could
interact with a host of prescription drugs, said Gurley, who is
studying the herb. Citrus aurantium inhibits an enzyme, known as
CYP3A4, in the small intestine that can alter the metabolism of drugs,
boosting their activity.

'We know this enzyme is responsible for the metabolic activity of 50%
of all prescription medications,' he said."

Ephedra Attorney
http://www.ephedraattorney.com/news/12092002.html

I hope this information is useful in helping you to make a decision
about this drug. If anything is unclear, or if a link doesn't work for
you, please request clarification; I'll gladly offer further
assistance before you rate my answer.

Best wishes,
pinkfreud
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