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Subject:
trimethoprim/sulfamethoxazole
Category: Health > Conditions and Diseases Asked by: spark72-ga List Price: $7.00 |
Posted:
31 Mar 2004 19:51 PST
Expires: 30 Apr 2004 20:51 PDT Question ID: 323330 |
Is trimethoprim/sulfamethoxazole, or trimethoprim by itself, commonly used or recommended to doctors in treating gastrointestinal infections or wounds that have become infected? Or is trimethoprim/sulfamethoxazole commonly used in hospitals and given to patients involved in trauma? |
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There is no answer at this time. |
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Subject:
Trimethoprim / Sulfamethoxazole
From: ctheronj-ga on 31 Mar 2004 19:59 PST |
This medication, commonly known as Bactrim or Septra, is an antibiotic most commonly used in treating urinary tract infections but it is useful against a wide range of bacterial infections. It works in combination, so trimethoprim alone is generally not used or available. It would probably not be the first choice in wound infections, GI infection, or trauma patients, but this would vary widely depending on circumstance. |
Subject:
Re: trimethoprim/sulfamethoxazole
From: synarchy-ga on 31 Mar 2004 20:12 PST |
Septra gets more use in those circumstances than you might have thought - a trauma patient/GI infection/Wound infection with coexisting UTI is commonly prescribed Septra if there is no other suspected infection or if the antibiotic coverage of the primary infection has been narrowed by sensitivity testing to the point that it would not cover a coexisting UTI. Also, at least here in North Carolina, a fair amount of the MRSA (methacillin resistant staph aureus) is only sensitive to Septra or Vancomycin. Being that Septra is available orally, is much, much cheaper, and reduces the risk of developing vancomycin resistant MRSA, it is getting a fair amount of use in treating MRSA positive patients (who could fit into either of those categories mentioned above.) Trimethoprim as sole therapy is really only seen in uncomplicated UTI's. The combination of sulfamethoxazole extends the spectrum of the drug considerably, but is not always needed for UTI's. |
Subject:
Re: trimethoprim/sulfamethoxazole
From: voila-ga on 31 Mar 2004 22:24 PST |
According to this document, TMP-SMX is being used in antimicrobial therapy for a variety of foodborne pathogens -- primarily in pediatric and immunocompromised patients. http://www.cidrap.umn.edu/cidrap/content/fs/food-disease/gastro-treat/tx-gastro.html |
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