I'm producing my first low budget independent Film a Romantic/Comedy.
My first choice is Patrick Dempsey, but it has been so hard to find
him. Please help me, I need to make sure he get's the Screenplay.
Someone told me that agent's don't help if theres little money
involved for them. PLEASE HELP! My second choice is John Cusack also
need his Contact info. Thanks! Gladys A.

Hi Gladys,

Since you are producing movies, and will probably need contact
information for various actors over a period of time, and whose
details are not easily accessible, you may want to subscribe to
"Contact Any Celebrity".

http://contactanycelebrity.com/

"Your monthly membership includes...
Instant access to over 16,000 accurate celebrity contacts via our
exclusive online database!
  
Unlimited database searches, twenty-four hours a day, seven days a week!
  
Representation information for each celebrity, including their agent,
manager, publicist, attorney, and financial manager if available!
  
Production company, record label, and entertainment industry contacts,
including contacts for the current season's TV shows!
  
The ability to request any contacts that we don't already have!..."


I checked their database and both actors you are looking for are included. 

However, since I am not a registered member, I am not able to access
their information.

I hope that helps.

Regards,
Rainbow

Another idea: 

IMDB Pro subscription could provide you more information on contacts,
projects the actor is involved in, etc.

www.imdb.com