Trying to find the paper presented by Milton Packer at the 49th Annual
meeting of the American College of Cardiology on march 12-15 2000
entitled PRAISE 2: Prospective Randomized Amlodipine Survival
Evaluation.

Hi Christine,

Dr. Packer presented the findings of the PRAISE-2 study, which was
published in the American Heart Journal.  A summary, and the fact that
this was the paper he presented, can be found at:
[ http://www.chfpatients.com/meds.htm#amlodipine2 ]

The abstract can be found on PubMed at: 
[ http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14691434&dopt=Abstract
]

The link for the full article from PubMed does NOT work.  Rather, I
found the full-text article at:
[ http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W9H-4B89Y8P-16&_user=10&_handle=B-WA-A-A-BY-MsSAYWA-UUA-AUEACAWDCD-AUYEUEBCCD-CUWBYCZAA-BY-U&_fmt=full&_coverDate=01%2F31%2F2004&_rdoc=29&_orig=browse&_srch=%23toc%236683%232004%23998529998%23475124!&_cdi=6683&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=0197352b719bc0c77c4e09e12e059e8d
]

I should note that it appears Dr. Packer was NOT one of the authors,
and I find it unusual that someone other than the author would present
the study, however this depends on the scale and scope of the meeting
and other factors.


I trust this information has shed light on your question, but if you
require a clarification, please request one, especially before rating
this answer.  Thank you for bringing this question to Google Answers!

Regards,
Andrewxmp


Search terms used:
"Milton Packer" "Prospective Randomized Amlodipine Survival"
Elsevier
"Am Heart J. 2004 Jan;147(1):151-7."

---

Request for Answer Clarification by christine32-ga on 05 Jul 2004 15:59 PDT

The study provided was done from the PRAISE 2 results, but was not the
paper written by Dr. Packer and presented at that meeting, clarifying
why the results of PRAISE 1 and PRAISE 2 were so different...thanks
for the try

---

Clarification of Answer by andrewxmp-ga on 05 Jul 2004 19:59 PDT

I'm very sorry about the mistake. I felt as though the paragraph at [
http://www.chfpatients.com/meds.htm#amlodipine2 ]implied this was the
paper you were referring to, but apparently not.

I did a more intensive search, and found two articles that may be the
ones you are looking for:

1) "Circadian rhythm and sudden death in heart failure: results from
Prospective Randomized Amlodipine Survival Trial
The purpose of this study was to address the timing of sudden death in
advanced heart failure patients."
"We analyzed data from Prospective Randomized Amlodipine Survival
Trial (PRAISE). Sudden deaths were analyzed by time of death in 4-h
and 1-h blocks for uniformity of distribution in the entire cohort,
and in the prespecified ischemic and nonischemic stratum. Further
analyses were undertaken in the treatment groups of amlodipine and
placebo, and among those receiving background therapy of aspirin and
warfarin."
[ http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T18-40TY46P-10&_coverDate=08%2F01%2F2000&_alid=184143586&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=4884&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=09e9e9d137702f9c2b244e306ad92800
]

2) "Clinical trials update: OPTIME-CHF, PRAISE-2, ALL-HAT 
This is a summary of reports of presentation made at the American
College of Cardiology 49th Scientific Sessions, Anaheim, 12?15 March
2000. Studies with a particular interest for heart failure physicians
have been reviewed.
[ http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VS9-424KY1R-G&_coverDate=06%2F01%2F2000&_alid=184143038&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=6257&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=64bdbcae1ab8bda8aed791a38588151b
]"


The first one lists Packer as an author, and seems to fit your
description.  The second one does not list him as an outhor, but
otherwise seems to fit, a a follow-up to the PRASE-2 study.

Please let me know if these are the studies you are looking for.  In
either case, I'll keep persistantly looking....