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Q: Allergy Question ( Answered 5 out of 5 stars,   0 Comments )
Question  
Subject: Allergy Question
Category: Health > Children
Asked by: aj_work-ga
List Price: $10.00
Posted: 10 Aug 2004 14:10 PDT
Expires: 09 Sep 2004 14:10 PDT
Question ID: 386050
If my daughter is allergic to peanuts, what are the chances my newborn son is also?
Answer  
Subject: Re: Allergy Question
Answered By: pinkfreud-ga on 10 Aug 2004 14:39 PDT
Rated:5 out of 5 stars
 
Studies indicate that if a child has a peanut allergy, the chance that
a sibling will also be allergic to peanuts is around 7%.

"Q: I have a child with peanut allergy. What are the chances of a
younger sibling developing it?

 A: Because there is allergy in your family, there is a high chance
that the younger sibling will also be prone to allergies. But these
will not necessarily be severe. There is only a seven per cent risk of
this second child developing peanut allergy, compared with a 1-2 per
cent risk in a child from a non-allergic family."

Some commonly asked questions: Some commonly asked questions 
http://www.anaphylaxis.org.uk/questions.html 
 
"Skin prick testing of 50 children with reported peanut allergy and
their families: 7 probands (14%) had a negative result for peanut.
Peanut allergy was refuted by food challenge in all those tested
(5/7). No parent and 13% (5/39) of siblings had a positive result on
skin prick testing for peanut. Two of these siblings had negative
challenge with peanuts. The prevalence of peanut allergy in siblings
is therefore 3/39 (7%)."

PubMed: Peanut allergy in relation to heredity
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8789975

"In a study on the genetics of peanut allergy, we found that there is
a 7% risk for peanut allergy in a sibling of a peanut allergic child."

WebMD: Peanut and Other Food Allergies 
http://my.webmd.com/content/article/71/81475.htm

"Genetics play a significant role in peanut allergy say a group of
researchers in the July 2000 Journal of Allergy and Clinical
Immunology... Fifty-eight pairs of twins (14 identical and 44
fraternal) were recruited for this study with at least one member of
each pair having a convincing history of peanut allergy. Seventy
individuals had a history of peanut allergy.

In 64 percent of the identical twin pairs, both twins were allergic to
peanuts, whereas in the fraternal twin pairs, both twins had peanut
allergy 7 percent of the time."

About Allergies: Peanut Allergy May Have Genetic Link
http://allergies.about.com/cs/research/a/blpeanutgenetic.htm

"With peanuts, studies show that a child has a 1-2% chance of having
peanut allergy if the parent is allergic and a 6-10% chance if a
sibling has it."

Parkhurst Exchange: Allergy
http://www.parkhurstexchange.com/qa/A.php?q=/qa/Allergy/2000-02-41.qa 

Google search strategy:

Google Web Search: allergy OR allergic sibling percent OR chance
://www.google.com/search?hl=en&ie=UTF-8&q=allergy+OR+allergic+sibling+percent+OR+chance

Google Web Search: risk sibling allergy peanut OR peanuts
://www.google.com/search?hl=en&ie=UTF-8&q=risk+sibling+allergy+peanut+OR+peanuts

I hope this helps. If anything is unclear, please request
clarification; I'll be glad to offer further assistance before you
rate my answer.

Best regards,
pinkfreud
aj_work-ga rated this answer:5 out of 5 stars
Great succinct introduction and comprehensive answer.

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