I am  a  man of 58.
I am taking Effexor since 2, 5  years (37,5 mg) after a minor
depression. Could there be any connexion with my neuropathy?  My first
symptoms of neuropathy showed up about 9 months after starting the
Effexor treatment.

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I found some references listing a possible connection of Effexor and neuropathy:

"ADVERSE REACTIONS"
...
Nervous system -- 
Frequent: emotional lability, trismus, vertigo; 
Infrequent: apathy, ataxia, circumoral paresthesia, CNS stimulation,
euphoria, hallucinations, hostility, hyperesthesia, hyperkinesia,
hypotonia, incoordination, libido increased, manic reaction,
myoclonus, neuralgia, neuropathy,"
from:
Drugs.com 
( http://www.drugs.com/PDR/Effexor_Tablets.html )

Another source states neuropathy as an infrequent effect as well:

"Nervous system - 
Frequent: amnesia, confusion, depersonalization, emotional lability,
hypesthesia, vertigo;
Infrequent: apathy, ataxia, circumoral paresthesia, CNS stimulation,
euphoria, hallucinations, hostility, hyperesthesia, hyperkinesia,
hypotonia, incoordination, libido increased, manic reaction,
myoclonus, neuralgia, neuropathy"
from:
Effexor Side Effects
( http://www.effexor-xr-side-effects-withdrawal.com/new-fda-effexor-report.html )

Source #3 again talks of infrequent effect:
"Infrequent (less than 1%): apathy, ataxia, CNS stimulation, euphoria,
hostility, hyperaesthesia, circumoral paraesthesia, hyperkinesia,
hypotonia, incoordination, manic reaction, myoclonus, neuralgia,
neuropathy, ..."
from:
Inhouse Pharmacy
( http://www.inhousepharmacy.com/anti-depressants/effexor-information.html )

So we can be quite sure that neuropathy  can be an adverse effect of
effexor. As the adverse effect is (in all sources I could find) listed
as "infrequent" it is not very probable, but of course possible.
Again I want to emphasise my recommendation to ask your doctor for
advice, maybe he will prescribe another medicinal drug for your
indication without this undesired effect.

I hope this helps to solve your problem. If anything should still be
unclear please post a clarification request.

till-ga


Search strategy:
( ://www.google.de/search?sourceid=navclient&hl=de&ie=UTF-8&q=Effexor+neuropathy
)
and
( ://www.google.de/search?sourceid=navclient&hl=de&ie=UTF-8&q=Effexor+neuropathy+adverse+reaction
)

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Request for Answer Clarification by robert22-ga on 18 Sep 2004 06:09 PDT

I would like to give you some complimentary informations; I have been
diagnosed with a Charcot Marie Tooth two years ago. But I think I've
had a sleeping CMT because of my hammertoes and arched feet as my
mother also had. I would like to know if taking Effexor could
transform a sleeping CMT into an active state of the disease CMT?

---

Clarification of Answer by till-ga on 18 Sep 2004 07:43 PDT

Sorry, but this request for clarification is far beyond the scope of
the original question. Please post this as a new question.

till-ga