Request for Question Clarification by
pinkfreud-ga
on
22 Sep 2004 22:24 PDT
The article that you mention is discussing cold-induced rhinitis (also
called "cold-induced rhinorrhea" or "skier's nose"). This is a
condition in which a person develops a watery, runny nose in response
to cold weather.
I believe the drug referred to in the article is ipratropium bromide
nasal spray, one of the most effective drugs for this condition. After
having been used in Europe, this drug is now available by prescription
in the United States.
"Cold-induced rhinitis in skiers--clinical aspects and treatment with
ipratropium bromide nasal spray: a randomized controlled trial.
Bonadonna P, Senna G, Zanon P, Cocco G, Dorizzi R, Gani F, Landi M,
Restuccia M, Feliciello A, Passalacqua G.
Allergy Unit, Verona General Hospital, Italy.
Cold-induced rhinitis (CIR) is common among skiers and is perceived as
a troublesome disease. We studied the clinical characteristics of CIR
in a population of skiers and we evaluated the effectiveness of
ipratropium bromide nasal spray (IBNS) in relieving symptoms in a
double-blind placebo-controlled fashion. By means of specific
questionnaires, we evaluated 144 subjects (69% men; mean age, 42.2
years). The prevalence of CIR was 48.6% and the distinctive symptom
was rhinorrhea (96%), often severe. The prevalence of atopy was higher
in the CIR patients (chi2; p = 0.004). Twenty-eight CIR subjects
participated in a double-blind placebo-controlled cross-over trial for
evaluating the effectiveness of IBNS (80 microg twice per day
[b.i.d.]). The severity of symptoms was assessed by a visual analog
scale, and the number of cleaning tissues used also was evaluated. The
actively treated group showed a significant improvement of rhinorrhea
(p = 0.0007) and a reduction in the number of cleaning tissues used (p
= 0.0023). Only four mild local side effects were reported. We
conclude that IBNS could be regarded as an optimal therapeutic option
for treating CIR symptoms in skiers."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11732814
If this is the correct drug, I'll be glad to gather more information
about it for you.