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Q: Information about a drying nasal spray developed in Europe ( No Answer,   0 Comments )
Question  
Subject: Information about a drying nasal spray developed in Europe
Category: Health > Medicine
Asked by: wannarun-ga
List Price: $15.00
Posted: 22 Sep 2004 19:32 PDT
Expires: 10 Oct 2004 18:13 PDT
Question ID: 405102
"Don't be tempted to try regular use of non-prescription nose drops or
spray to relieve congestion. They work temporarily, but eventually
cause rebound swelling that leaves you even more congested in the long
run. There will be a drying nasal spray developed in Europe available
in the near future, then you may want to obtain a prescription and try
this new drug."

From: http://www.americanrunning.org/displayindustryarticle.cfm?articlenbr=1675

What is the name of this drying nasal spray?

Where can I find more information about it and when/if it will be
availible in the US or even if/how I can get it from Europe?

Thanks!

Request for Question Clarification by pinkfreud-ga on 22 Sep 2004 22:24 PDT
The article that you mention is discussing cold-induced rhinitis (also
called "cold-induced rhinorrhea" or "skier's nose"). This is a
condition in which a person develops a watery, runny nose in response
to cold weather.

I believe the drug referred to in the article is ipratropium bromide
nasal spray, one of the most effective drugs for this condition. After
having been used in Europe, this drug is now available by prescription
in the United States.

"Cold-induced rhinitis in skiers--clinical aspects and treatment with
ipratropium bromide nasal spray: a randomized controlled trial.

Bonadonna P, Senna G, Zanon P, Cocco G, Dorizzi R, Gani F, Landi M,
Restuccia M, Feliciello A, Passalacqua G.

Allergy Unit, Verona General Hospital, Italy.

Cold-induced rhinitis (CIR) is common among skiers and is perceived as
a troublesome disease. We studied the clinical characteristics of CIR
in a population of skiers and we evaluated the effectiveness of
ipratropium bromide nasal spray (IBNS) in relieving symptoms in a
double-blind placebo-controlled fashion. By means of specific
questionnaires, we evaluated 144 subjects (69% men; mean age, 42.2
years). The prevalence of CIR was 48.6% and the distinctive symptom
was rhinorrhea (96%), often severe. The prevalence of atopy was higher
in the CIR patients (chi2; p = 0.004). Twenty-eight CIR subjects
participated in a double-blind placebo-controlled cross-over trial for
evaluating the effectiveness of IBNS (80 microg twice per day
[b.i.d.]). The severity of symptoms was assessed by a visual analog
scale, and the number of cleaning tissues used also was evaluated. The
actively treated group showed a significant improvement of rhinorrhea
(p = 0.0007) and a reduction in the number of cleaning tissues used (p
= 0.0023). Only four mild local side effects were reported. We
conclude that IBNS could be regarded as an optimal therapeutic option
for treating CIR symptoms in skiers."

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11732814

If this is the correct drug, I'll be glad to gather more information
about it for you.
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