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Q: Genetics question ( Answered 5 out of 5 stars,   1 Comment )
Subject: Genetics question
Category: Science > Biology
Asked by: jennifer1000-ga
List Price: $2.00
Posted: 04 Oct 2004 22:27 PDT
Expires: 03 Nov 2004 21:27 PST
Question ID: 410450
In Guinea pigs long hair is domonant over short hair and black is
dominant over white. A homozygous long haired, black guinea pig mated
to a short haired, white guinea pig. Give the genotypes and phenotypes
of the parents and the F1. If the F1 are allowed to breed freely among
themselves what are the expected phenotypes and genotypes in the F2
and what is the phenotypic ratio of the F2?
Subject: Re: Genetics question
Answered By: librariankt-ga on 05 Oct 2004 06:19 PDT
Rated:5 out of 5 stars
Hi Jennifer,

Let's call our gene in this case L (long hair) vs. l (short hair) and
B (black) vs. b (white).

You have one LLBB guinea pig (homozygous for both) mated to a llbb
guinea pig.  You know that the short-haired, white guinea pig MUST be
homozygous for the recessive alleles (l and b) because otherwise it
would be long-haired and black.

So, the parents are LLBB and llbb.

The F1 generation (first children) will ALL be heterozygous for both
genes - meaning they will be 100% LlBb, and 100% phenotypically
long-haired and black.

At this point the phenotypes and genotypes for the F2 (grandchildren)
are a standard Mendelian cross using two genes - which you can figure
out using a 4x4 table.  Each parent can contribute four pairings of
alleles (LB, Lb, lB, or lb), making 16 possible genotype combinations
(number in parentheses is the statistical ratio that the pair will
show up):

LLBB (1/16) - long hair, black
LLBb (2/16) - long hair, black
LLbb (1/16) - long hair, white
LlBB (2/16) - long hair, black
LlBb (4/16) - long hair, black
Llbb (2/16) - long hair, white
llBB (1/16) - short hair, black
llBb (2/16) - short hair, black
llbb (1/16) - short hair, white

The ratios of phenotype are the standard for a heterozygous cross (9:3:3:1):

9 long/black
3 long/white
3 short/black
1 short/white

The links I gave you on a previous question are also applicable to
this one, so I refer you back to them.  This is basic Mendelian
Genetics, and while complicated and a bit confusing, is really just
probability and statistics.  Let me know if anything's not clear!

jennifer1000-ga rated this answer:5 out of 5 stars and gave an additional tip of: $1.00

Subject: Re: Genetics question
From: politicalguru-ga on 05 Oct 2004 01:12 PDT
Thank you for your question.  
However, I believe that to answer it well, your question will require
more time and effort than the average amount of time and effort
associated with this price. Here is a link to guidelines about pricing
your question, in the pricing guide:

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