When does gadolinium come off patent. Further information re: possible
generic suppliers and pricing would be helpful (and may generate more
money for answer).

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Request for Question Clarification by pinkfreud-ga on 14 Nov 2004 11:52 PST

Is this the substance you're asking about?

http://www.mrsc.ucsf.edu/breast/gadolinium.html

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Clarification of Question by drrjv-ga on 14 Nov 2004 12:37 PST

Yes. Compound goes under brand name of Magnevist or Prohance.

Gadolinium is an element. Elements cannot normally be patented.

http://www.webelements.com/webelements/elements/text/Gd/key.html

In addition to Magnevist and Prohance, Dotarem and Omniscan are two
other Gd-based contrast media.

http://www.mr-tip.com/serv1.php?type=db1&dbs=dotarem

http://www.mr-tip.com/serv1.php?type=db1&dbs=omniscan

Sorry if I was not clear. My question is in regards to when the MRI
contrast agent, called gadolinium generically and Magnevist
(Gadopentetate Dimeglumine) or Prohance (gadoteridol) by Brand name
come off patent and when will generic versions of these compounds be
made available.

Here are some links with more information:

http://www.berlex.com/html/products/pi/Magnevist_PI.pdf

http://www.berleximaging.com/magnevist/product_info.html;jsessionid=9A0FA9F2747BFF7FA2CD918B0CEF57D3

http://www.amershamhealth.com/medcyclopaedia/medical/volume%20i/mr%20contrast%20medium.asp

http://www.bracco.com/Bracco/Internet/Imaging/MRI/#

The patent term is 20 years from the filing date.

6,493,571 
Bis ,   et al. 
Filing Date: June 12, 2000
Issue Date: December 10, 2002 
 
Rapid magnetic resonance imaging and magnetic resonance angiography of
multiple anatomical territories

This patent expires on June 12, 2020

For Magnevist:
http://www.thinkpharm.com/patent/preview/detail/index.php?searchtype=alpha&category=Tradename&searchstring=MAGNESIUM%20SULFATE%20IN%20PLASTIC%20CONTAINER

Depending on the form, at the latest, 10/01/2013

Prohance:
http://www.thinkpharm.com/patent/preview/detail/index.php?searchtype=alpha&category=Tradename&searchstring=PROHANCE

Answer: 12/12/2012

I came across this web site too. It is not really clear as to when the
compound will come off patent. I searched the US Patent Office web
site without much success although the Canadian patent office
indicated that it came off patent there earlier this year.

More specific information is required. Thanks for looking.