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Subject:
Mobile genetic elements
Category: Science > Biology Asked by: msjoyce-ga List Price: $12.00 |
Posted:
29 Nov 2004 12:42 PST
Expires: 29 Dec 2004 12:42 PST Question ID: 435643 |
I am currently researching ICE's - Integrative and Conjugative Elements, using a review called Conjugative transposons: the tip of the iceberg, by Vincent Burrus, et al, and published in Molecular Microbiology (2002), 46: 601-610. What I specifically need to know is what distinguishes these elements from typical plasmids, transposons and other mobile elements etc, as the paper is very confusing. |
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There is no answer at this time. |
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Subject:
Re: Mobile genetic elements
From: robd1752-ga on 11 Dec 2004 11:44 PST |
I'm not going to look at the paper, but I can clarify a few things. Plasmids can be transmitted by bacterial conjugation, but they are by definition extra-chromosomal elements, and do not integrate into the recipient's genome. Transposons do integrate into the host genome, but are not transmitted between bacteria by conjugation The elements these people are talking about do both, and that's what makes them interesting. In animals you see a continuum from retroviruses, to those that lost the ability to replicate outside the cell and have become transposons. I guess this shows that an similar thing occurs in bacteria with plasmids. |
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