I found the following information on a website linked to Harvard
Medical School some 2 or 3 years ago. I have since tried to obtain
further details but without success. I have contacted one of the
authors, I think Twiggs, but he was the statstical analzyer and was
unable to help me. I am looking to find out whatever happened to these
projects/papers, and/or have email contact details for the various
authors. In particular S. Ramakrishnan would interest me.

The following trials were carried at at Harvard
Medical School

Ghosh K., Wild R., Carson L.F., Twiggs L.B., and
Ramakrishnan S. Noscapine, a novel agent that induces
cytotoxicity and apoptosis in cervical cancer cells.
(Manuscript in Preparation)


Ghosh K., Wild R., Carson L.F., Twiggs L.B., and
Ramakrishnan S. Noscapine: a new drug with antitumor
activity in breast cancer. (Manuscript in
Preparation)"

Dear solars,

Although it proved impossible to find information on what became of
the project papers, my research has produced results that should be
useful. I am sure that I have successfully identified three of the
five authors, L. F. Carson, S. Ramakrishnan and L. B. Twiggs. Much to
my surprise, they are all members of the University of Minnesota
faculty, in the departments of Obstetrics and Gynecology respectively
of Pharmacology, where they concern themselves among other issues with
cancer research.



-- Linda Frances Carson, M.D. --
Professor at the University of Minnesota, Department of Obstetrics and Gynecology.

Contact information:

Linda F. Carson
Obstetrics and Gynecology
12-284 Moos T
515 Delaware St SE
Minneapolis, MN 55455
 -
Phone: 612-626-4338
E-Mail: carso001@umn.edu



-- Sundaram Ramakrishnan, Ph.D. --
Associate Professor at the University of Minnesota, Department of Pharmacology.

Contact information:

Sundaram Ramakrishnan
Pharmacology
3-134 BS and BE
312 Church St SE
Minneapolis, MN 55455
 -
Phone: 612-626-6461
E-Mail: sunda001@umn.edu
Website: http://www.pharmacology.med.umn.edu/stafframakrishnan.html



-- Leo Brookhart Twiggs, M.D. --
Professor at the University of Minnesota, Department of Obstetrics and Gynecology.

Contact information:

Leo B. Twiggs
Obstetrics and Gynecology
12-216 Moos T
515 Delaware St SE
Minneapolis, MN 55455
 -
Phone: 612-626-3347
E-Mail: twigg001@umn.edu




I hope that this contact information will be useful for you!
Best regards,
Scriptor





Sources:

University of Minnesota Cancer Center: Gynecological Cancer
http://www.cancer.umn.edu/page/clinical/gyneca.html

Women's Cancer Center: Physicians
http://www.wccenter.com/cvmdc.html

University of Minnesota: Pharmacology Faculty
http://www.pharmacology.med.umn.edu/faculty.html

American Medical Association: Physician Database
http://dbapps.ama-assn.org/iwcf/iwcfmgr206/SESSION_ID=3681231/SESSION_AR=576/frm_name=aps_disclaimer

Cancer Research: Vascular permeability factor gene expression in
normal and neoplastic human ovaries
http://cancerres.aacrjournals.org/cgi/content/abstract/54/1/276

Journal of the American Medical Association: Archive
http://jama.ama-assn.org/search.dtl

University of Minnesota: People Search
http://www1.umn.edu/twincities/00_peoplesearch.php


Search terms used:
"university of minnesota" carson pharmacology
://www.google.de/search?hl=de&newwindow=1&q=%22university+of+minnesota%22+carson+pharmacology&btnG=Suche&meta=
"linda f carson"
://www.google.de/search?hl=de&q=%22linda+f+carson%22&btnG=Google-Suche&meta=
"leo b twiggs"
://www.google.de/search?hl=de&newwindow=1&q=%22leo+b+twiggs%22&btnG=Suche&meta=
"ramakrishnan ph d"
://www.google.de/search?hl=de&newwindow=1&q=%22ramakrishnan+ph+d%22&btnG=Suche&meta=
"ghosh phd"
://www.google.de/search?hl=de&q=%22ghosh+phd%22&btnG=Google-Suche&meta=
"leo twiggs" harvard cancer
://www.google.de/search?hl=de&newwindow=1&q=%22leo+twiggs%22+harvard+cancer&btnG=Suche&meta=
"l f carson" "harvard medical school"
://www.google.de/search?hl=de&newwindow=1&q=%22l+f+carson%22+%22harvard+medical+school%22&btnG=Suche&meta=
"Obstetrics and Gynecology" "linda carson"
://www.google.de/search?hl=de&newwindow=1&q=%22Obstetrics+and+Gynecology%22+%22linda+carson%22&btnG=Suche&meta=

well done, and extremely fast

Noscapine is a compound that is still under pre-clinical investigation
for cancer therapy.  Probably the original notice you found for these
manuscripts was a bulletiin board message.   The following link
contains the orriginal information.
http://www.cancerconf.com/physicians/bulletin_board/messages/16.html

A simple search at the National Library of Medicines PubMed website,
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi , will give you the
latest publications on the subject.    Any paper that is listed as
being in preparation should not be taken as vaporware.    Though I
don't know what the Noscapine project was with the U Minn group, the
only Clinical Trial that I could find was run at the USC Norris Cancer
center looking at the effects on lymphoma.
http://ccnt.hsc.usc.edu/ClTrials/ViewProtocol.aspx?protocol_num=0C-99-16&protocol_id=1212
.

Though I don't know Scriptor-ga from the above reply I suspect he is
not a biomedical researcher and is just not familar with the field. 
If you are specifically interested in the latest advances in clinical
treatement in the United States please check,
http://clinicaltrials.gov/.  This site keeps up with all the latest
clinical trials being funded or monitored by the National Insitutes of
Health.