Hi again 11boomer,
I found your information in a 2003 Annual Report put out by Allergan.
Allergan spent 200 Million in three years: 2000, 2001, and 2003; in
R&D projects relating specifically to further development (and
regulatory approval for new uses) of Botox. Migraine treatment is not
broken out specifically, and the 2004 numbers are not out yet, however
by extrapolation, this number would now be 266 Million.
Bottom of Page 12:
http://www.shareholder.com/AGN/downloads/2003AnnualReport.pdf
..."With 15 years of history in the United States, approval in 73
countries around the world and over 1 million patients treated with
BOTOX in 2002 alone,BOTOX has a virtually unparalleled record in the
pharmaceutical industry of use for many serious medical conditions.
Allegan continues to invest heavily in BOTOX R&D; over $200 million in
the past three years, to investigate and secure regulatory approval
for new indications for BOTOX as well as to further improve the
product..."
Additionally, Allergan spent 305 Million in 2003 for R&D. By dividing
the 200 Million figure above by three (for 2003 only), new
applications for the Botox product used 21.786% of those Research
dollars. Indeed, new uses and further development of Botox is high on
their agenda. Of course my numbers are very rough, but you get the
idea.
The PDF document above is 52 pages, I skimmed it for relevant facts,
but you may want to read it all.
The information below is available here:
http://www.botox.com/site/consumers/home.asp
BOTOX® is currently approved for the following conditions:
Blepharospasm (approved December 1989)
..."is a disorder of the muscles that control eyelid movement..."
Cervical Dystonia (approved in 2000)
..."Patients with CD have involuntary contractions of the neck and
shoulder muscles that cause the head to twist in abnormal
positions..."
Severe Primary Axillary Hyperhidrosis that is inadequately managed by
topical agents. (date ?)
..." or severe underarm sweating, is a medical condition that involves
hyperactive sweat glands..."
Strabismus (approved December 1989)
..."also known as crossed eyes, is a disorder in which eyes are misaligned..."
For information on BOTOX® approved uses in countries outside of the
United States, please see our global contacts list.
I went to the Allergan web site and they are having a live "webcast"
in regards to 4th Quarter 2004 earnings...
http://www.allergan.com/site/
..."A live Webcast can be heard Monday, February 7, 2005 at 7 a.m. (Pacific Time)
A replay will be available through Friday, February 11, 2005 at 9 p.m
(Pacific Time)..."
By clicking on R&D, you are taken to a a page with many links to
follow that describe the entire development of new drugs, it's
fascinating.
Here's a page for Botox Research Strategies:
http://www.allergan.com/site/r_and_d/research_neuromuscular_disorders.asp
You can look at all of their recent Annual Reports (and other filings) here:
Annual Reports - Financial Downloads
http://www.shareholder.com/AGN/annual_download.cfm?id=&largeText=
To locate information quickly in these long PDF documents, click on
the BINOCULARS in the toolbar. This opens a SEARCH BOX. Enter
keywords and click on the results in the right pane to see if they are
relevant to your search.
You may find more relevant results here:
SEC Filings
http://www.shareholder.com/AGN/edgar.cfm
I hope this information is satisfactory. If I can be of further
assistance in regards to R&D costs for new uses of Botox, please don't
hesitate to ask via the "Request For Clarification" feature.
~~Cynthia
Search terms used at Google:
allergan botox migraine research
botox "cost of development"
"botox cost * to develop" migraine
botox R&D "white paper" migraine |
