![]() |
|
![]() | ||
|
Subject:
biochemistry --blood test
Category: Science Asked by: starshower-ga List Price: $5.00 |
Posted:
11 Feb 2005 16:18 PST
Expires: 13 Mar 2005 16:18 PST Question ID: 473133 |
Do lab test scores for FREE T-3 and FREE T-4 exclude all the molecules that have been bound with antibodies? |
![]() | ||
|
There is no answer at this time. |
![]() | ||
|
Subject:
Re: biochemistry --blood test
From: john_s-ga on 21 Feb 2005 09:41 PST |
I thought T-3 and T-4 were iodine. The thyroid uses these forms of iodine and a low score on this indicates low iodine levels. Low iodine levels may be problematic to health and cuase goiters. : ) |
Subject:
Re: biochemistry --blood test
From: wileecoyote-ga on 23 Feb 2005 02:44 PST |
If the lab test is a direct measurement, then free T3 (FT3) and free T4 (FT4) values are unbound concentrations in respect to binding to thyroxine-binding globulin (TBG). The predominant binding protein of thyroxine is TBG, in which ~98% of the hormone is bound. Most blood tests for FT3/4 (such as radio-immunoassays, ELISA, etc.) utilize antibodies which bind each of the hormones. As such, special instances are plausible in which an exiting antibody-hormone complex could affect the measured free hormone levels. If the antibody used in the FT3/4 assay binds the SAME epitope as the pre-bound antibody (in blood sample), then the assay WILL NOT recognize the T3/T4 as a free molecule. Likewise, if the two antibodies have DISTINCT epitopes which do not intefere with each other's binding abilities, then the FT3/4 assay WILL recognize the T3/T4 as a free molecule. Hope this helps. -SG |
If you feel that you have found inappropriate content, please let us know by emailing us at answers-support@google.com with the question ID listed above. Thank you. |
Search Google Answers for |
Google Home - Answers FAQ - Terms of Service - Privacy Policy |