can anyone tell me what company originally developed this drug?  It
was stopped in development due to safety issues but I can't track down
which company was investigating it.  THanks!

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Request for Question Clarification by pinkfreud-ga on 24 Feb 2005 13:00 PST

Please let me know if this is the information you seek:

"In 1982, Takeda Chemical Industries, in Osaka, Japan, identified the first
thiazolidinedione, called ciglitazone, in its search for an agent that
had lipid-lowering properties."

www.fda.gov/ohrms/dockets/ac/99/transcpt/3507t2a.pdf

"The lead for the drug discovery programme was the thiazolidinedione,
ciglitazone, found in the early 1980s by Takeda, when searching for
fibrate-like hypolipidaemic agents."

http://smr.org.uk/previous_meetings/reportdec97.pdf

If this is fully satisfactory, I'll be glad to repost this material as
your official answer. If this is not what you're looking for, it would
be very helpful if you could give us a few more details about your
needs.

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Clarification of Question by aprillee76-ga on 24 Feb 2005 14:30 PST

that's it, thanks

I am glad to have been able to help you find the information you need.
I've reposted it below.

"In 1982, Takeda Chemical Industries, in Osaka, Japan, identified the
first thiazolidinedione, called ciglitazone, in its search for an
agent that had lipid-lowering properties."

US Food & Drug Administration
www.fda.gov/ohrms/dockets/ac/99/transcpt/3507t2a.pdf

"The lead for the drug discovery programme was the thiazolidinedione,
ciglitazone, found in the early 1980s by Takeda, when searching for
fibrate-like hypolipidaemic agents."

The Society for Medicines Research
http://smr.org.uk/previous_meetings/reportdec97.pdf

My Google search strategy:

Google Web Search: ciglitazone "developed by"
://www.google.com/search?hl=en&q=ciglitazone+%22developed+by%22

Google Web Search: ciglitazone takeda
://www.google.com/search?hl=en&q=ciglitazone+takeda

Best regards,
pinkfreud