I need a list of the main symptoms/issues people have if they suffer
this genetic disorder.
ie: what are the main afflictions?, are there any published papers
describing this? and in wHat way are 'sufferers' (for want of a better
word) affected by it?
I know all the in and outs of how it happened etc... I just need the
facts as to what it means.
Regards
Kate

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Clarification of Question by oscarb-ga on 05 Mar 2005 14:15 PST

It would also be handy to know if there are any published suffers
within the UK. This info is good if you come across it, but I mainly
would like to know about the afflictions of it.

You could look at these articles:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11063809

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14734219

It would have no effect in the person in which it occured (assuming
the translocation points did not truncate any genes, i.e., the
translocation was balanced). However, it could have drastic (most
likely lethal) effects in the person's offspring. This is because of
unequal recombination that occurs in meiosis I.