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Q: Cabbage Juice for Ulcers ( Answered 5 out of 5 stars,   2 Comments )
Question  
Subject: Cabbage Juice for Ulcers
Category: Health > Alternative
Asked by: mades32388-ga
List Price: $20.00
Posted: 09 Mar 2005 15:33 PST
Expires: 08 Apr 2005 16:33 PDT
Question ID: 490388
I see lots of places online saying that cabbage juice has been proven
in clinical trials in the treatment of ulcers. I would like to find
out the exact details of this trial. Where the trial was conducted,
when (what year), how many people were involved, who the doctor was
etc. I'm tired of just reading about it without any facts.

Also, as a side note (& just for a tip - not required), I'd like to
know if there were any trials done with DGL (deglycyrrhizinated
licorice) & what the details of that were.

Please ask should you have any questions.
Answer  
Subject: Re: Cabbage Juice for Ulcers
Answered By: pinkfreud-ga on 09 Mar 2005 21:39 PST
Rated:5 out of 5 stars
 
There have been studies which found raw cabbage juice to be useful in
treating ulcers. The high glutamine and S-methylmethionine content of
cabbage may be responsible. The studies most often mentioned were
conducted between 1949 and 1952 at Stanford University by Dr. Garrett
Cheney.

"Cabbage (Brassicaoleracea) and its juice contain glutamine and
S-methylmethionine, two compounds with anti-ulcer properties.  Melvyn
Werbach, M.D., assistant clinical professor of psychiatry at the
University of California, Los Angeles, School of Medicine, and author
of Nutritional Influences on Illness, refers to a study using raw
cabbage juice showed remarkable improvement within three weeks,
compared with 32 percent of those taking placebo.  Dr. Garnett Cheney
at Stanford University?s School of Medicine, as well as other
researchers in the 1950s, found that cabbage juice was particularly
beneficial for peptic ulcers (Cal Med 70:10-14, 1949)."

The Baby Sam Show: Peptic Ulcers
http://www.thebabysamshow.com/Vits_Minerals/Peptic%20Ulcers.htm  

"Raw cabbage juice has been remarkably successful in treating ulcers.
One quart of the fresh juice is prepared daily and taken in divided
doses throughout the day. The juice can be prepared by using a
standard juicing machine or putting the cabbage along with some water
in a high-speed blender. In one study, this therapy produced complete
healing of ulcers in approximately ten days...

Cheney G. Rapid healing of peptic ulcers in patients receiving fresh
cabbage juice. Cal Med. 1949;70:10-14."

"Traditionally, raw cabbage juice has been used for stomach ulcers and
raw potato juice for duodenal ulcers. In the 1950s Dr. Garnett Cheney
of Stanford?s School of Medicine studied 181 patients, and found one
litre of raw cabbage juice daily to be highly beneficial. Green
cabbages are best, but red cabbages can also be used and it can be
mixed 50:50 with carrot and/or celery juice for flavor."

TrueStar Health: Natural Solutions for Stomach Ulcers
http://www.truestarhealth.com/members/cm_archives14ML3P1A22.html

NHI on Demand: Peptic Ulcer Disease 
http://content.nhiondemand.com/dse/consumer/HC3.asp?objID=100242&cType=hc#fn106997

"Garnett Cheney, M.D. had 100 peptic ulcer patients drink four glasses
of raw cabbage juice daily.  The patients reported dramatically less
pain, and X-ray examination confirmed faster healing time.  There was
no other change in their diet, and they did not have drug therapy. 
81% of the patients were symptom-free within one week; over two-thirds
were better in just four days.  The average healing time for patients
given standard hospital treatment was over a month. Cabbage juice
worked well for other types of ulcers, also.  (Cheney, G., 'Vitamin U
Therapy of Peptic Ulcer,' California Medicine, Vol. 77, Number 4,
October, 1952)."

Oradix: Home Remedies, Forgotten Cures 
http://www.oradix.com/health-library/idx/0/005/article/Home_Remedies_Forgotten_Cures_and_practical_Medical_Discoveries.html

"Consider the work of Garnett Cheney, M.D.  He had 100 peptic ulcer
patients drink a quart of raw cabbage juice daily.  The patients
reported dramatically less pain, and X-ray examination confirmed
faster healing time.  There was no other change in their diet, and
they did not have drug therapy.  81% of the patients were symptom-free
within one week; over two/thirds were better in just four days. 
Average healing time for patients given standard hospital treatment
was over a month.  (Cheney, G: "Vitamin U Therapy of Peptic Ulcer,"
California Medicine, vol. 77, number 4, October, 1952)

Dr. Cheney used cabbage juice to also treat gastric ulcers and
duodenal ulcers.  He clearly was onto something, which he called
'Vitamin U' (for ulcer) for lack of a better name."

Doctor Yourself: A NATURAL HEALING VIEWPOINT ON COLITIS, ULCER, AND
OTHER GI PROBLEMS
http://www.doctoryourself.com/colitis.html

"Many years ago, researchers reported that cabbage juice accelerated
healing of peptic ulcers.5 6 7 8 Drinking a quart of cabbage juice per
day was necessary for symptom relief in some reports. Although only
preliminary modern research supports this approach,9 many
nutritionally oriented doctors claim considerable success using one
quart per day for ten to fourteen days, with ulcer symptoms frequently
decreasing in only a few days...

5. Cheney G. Rapid healing of peptic ulcers in patients receiving fresh cabbage
juice. Cal Med 1949;70:10.

6. Doll R, Pygott F. Clinical trial of Robaden and of cabbage juice in
the treatment
of gastric ulcer. Lancet 1954;ii:1200.

7. Thaly H. A new therapy of peptic ulcer: The anti-ulcer factor of cabbage. Gaz
Med Fr 1965;72:1992?93.

8. Dunaevskii GA, Migonova DK, Rozka IM, Chibisova SM. Value of preserved
juice of white cabbage in the complex therapy of peptic ulcer. Vopr Pitan
1970;29:29?33."

Village Health Clinic: Peptic Ulcer
http://www.villagehealthclinic.ca/pdf/conditions/Peptic_Ulcer.pdf

"Lancet. 1954 Dec 11;267(6850):1200-4.

Clinical trial of Robaden and of cabbage juice in the treatment of gastric ulcer.

DOLL R, PYGOTT F."

PubMed Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=13213161

"Vopr Pitan. 1970 Jul-Aug;29(4):29-33.  

Value of preserved juice of white cabbage in the complex therapy of peptic ulcer.

[Article in Russian]

Dunaevskii GA, Migunova DK, Rozka IM, Chibisova SM."

PubMed Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=5492107

"Gaz Med Fr. 1965 May 10;72(9):1992-3.

A new therapy of peptic ulcer: "the anti-ulcer factor of cabbage" ("vitamin U")

[Article in French]

Thaly H."

PubMed Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=5839761

======================================================================

Regarding DGL:

"Animal studies and early trials in humans support the value of
licorice for stomach ulcers. One animal study recently found that
aspirin coated with licorice reduced the number of ulcers in rats by
50 percent. (High doses of aspirin often cause ulcers in rats).
Earlier studies in humans have found that preparations containing
glycyrrhizin (an active compound in licorice) may be as effective as
leading anti-ulcer medications in relieving pain associated with
stomach ulcers and preventing the ulcers from recurring. In one study,
licorice root fluid extract was used to treat 100 patients with
stomach ulcers (of which 86 had not improved from conventional
medication) for 6 weeks. Ninety percent of patients improved; ulcers
totally disappeared in 22 of these patients."

University of Maryland Medical Center: Licorice
http://www.umm.edu/altmed/ConsHerbs/Licoricech.html

(Be sure to examine the extensive list of reference sources at the
bottom of the University of Maryland page linked above.)

"A preliminary trial found that while the acid-blocking drug
cimetidine (TagametŪ) led to quicker symptom relief, chewable
deglycyrrhizinated licorice (DGL) tablets were just as effective at
healing and maintaining the healing of stomach ulcers. 5 Chewable DGL
may also be helpful in treating ulcers of the duodenum, the first part
of the small intestine. 6 Capsules of DGL may not work for ulcers,
however, as DGL must mix with saliva to be activated. 7...

5.  Morgan AG, McAdam WAF, Pacsoo C, Darnborough A. Comparison between
cimetidine and Caved-S in the treatment of gastric ulceration, and
subsequent maintenance therapy. Gut 1982;23:545-51.

6.  Kassir ZA. Endoscopic controlled trial of four drug regimens in
the treatment of chronic duodenal ulceration. Irish Med J
1985;78:153-6.

7.  Bardhan KD, Cumberland DC, Dixon RA, Holdsworth CD. Clinical trial
of deglycyrrhizinised liquorice in gastric ulcer. Gut 1978;19:779-82."

University of California, San Diego: Licorice 
http://myhealth.ucsd.edu/library/healthguide/en-us/Cam/topic.asp?hwid=hn-2122006

"In a study of DGL in gastric ulcer, 33 gastric ulcer patients were
treated with either DGL (760 mg, three times a day) or a placebo for
one month. There was a significantly greater reduction in ulcer size
in the DGL group (78%), than in the placebo group (34%). Complete
healing occurred in 44% of those receiving DGL, but in only 6% of the
placebo group.

Subsequent studies have shown DGL to be as effective as Tagamet and
Zantac for both short term treatment and maintenance therapy of
gastric ulcer. For example, in a head to head comparison with Tagamet,
one hundred patients received either DGL (760 mg, 3 times a day
between meals) or Tagamet (200 mg, 3 times a day and 400 mg at
bedtime). The percentage of ulcers healed after 6 and 12 weeks were
similar in both groups. Yet, while Tagamet is associated with some
toxicity, DGL is extremely safe to use...

DGL is also effective in duodenal ulcers. This is perhaps best
illustrated by one study in patients with severe duodenal ulcers. In
the study, forty patients with chronic duodenal ulcers of 4 to 12
years duration and more than 6 relapses during the previous year were
treated with DGL.21 All of the patients had been referred for surgery
because of relentless pain, sometimes with frequent vomiting, despite
treatment with bed rest, antacids, and powerful drugs. Half of the
patients received 3 grams of DGL daily for 8 weeks; the other half
received 4.5 grams per day for 16 weeks. All 40 patients showed
substantial improvement, usually within 5 to 7 days, and none required
surgery during the one year follow-up. Although both dosages were
effective, the higher dose was significantly more effective than the
lower dose...

1.  Berstad K and Berstad A: Helicobacter pylori infection in peptic
ulcer disease. Scand J Gasroenterol 28:561-7, 1993.

2.  Sarker SA and Gyr K: Non-immunological defense mechanisms of the
gut. Gut 33:987-93, 1992.

3.  Weil J, et al.: Prophylactic aspirin and risk of peptic ulcer
bleeding. BMJ 310:827-30, 1995.

4.  Gray GM: Peptic ulcer diseases. In, Dale DC, Federman DD:
Scientific American Medicine. Sci Am, New York, NY, 1995.

5.  Anda RF, Williamson DF, Escobedo L, et al: Self-perceived stress
and the risk of peptic ulcer disease. Arch Int Med 152:829, 1992.

6.  Feldman EJ and Sabovich KA: Stress and peptic ulcer disease.
Gastroenterol78:1087-9, 1980.

7.  Andre C, Moulinier B, Andre F, and Daniere S: Evidence for
anaphylactic reactions in peptic ulcer and varioliform gastritis. Ann
Allergy 51:325-8, 1983.

8.  Siegel J: Immunologic approach to the treatment and prevention of
gastrointestinal ulcers. Ann Allergy 38:27-9, 1977.

9.  Kumar N, Kumar A, Broor SL, et al: Effect of milk on patients with
duodenal ulcers. Brit Med J 293:666, 1986.

10. Rydning A, Berstad A, Aadland E, and Odegaard B: Prophylactic
effects of dietary fiber in duodenal ulcer disease. Lancet 2:736-9,
1982.

11. Kang JY, et al.: Dietary supplementation with pectin in the
maintenance treatment of duodenal ulcer. Scand J Gastroenterol
23:95-9, 1988.

12. Harju E, and Larme TK: Effect of guar gum added to the diet of
patients with duodenal ulcers. J Parenteral Enteral Nutr 9:496-500,
1985.

13. Cheney G: Rapid healing of peptic ulcers in patients receiving
fresh cabbage juice. Cal Med 70:10-14, 1949.

14. Cheney G: Anti-peptic ulcer dietary factor. J Am Diet Assoc 26:668-72, 1950. 

15. Shive W, Snider RN, DuBiler B, et al: Glutamine in treatment of
peptic ulcer. Tex J Med 53:840-3, 1957.

16. Marle, J, et al.: Deglycyrrhizinised liquorice (DGL) and the
renewal of rat stomach epithelium. Eur J Pharm. 72:219, 1981.

17. Morgan Ag, et al.: Comparison between cimetidine and Caved-S in
the treatment of gastric ulceration, and subsequent maintenance
therapy. Gut 23:545-51, 1982.

18. Kassir ZA: Endoscopic controlled trial of four drug regimens in
the treatment of chronic duodenal ulceration. Irish Med J 78:153-6,
1985.

19. Turpie AG, Runcie J and Thomson TJ: Clinical trial of
deglycyrrhizinate liquorice in gastric ulcer. Gut 10:299-303, 1969.

20. Rees WDW, et al.: Effect of deglycyrrhizinated liquorice on
gastric mucosal damage by aspirin. Scand J Gastroent 14:605-7, 1979.

21. Tewari SN and Wilson AK: Deglycyrrhizinated liquorice in duodenal
ulcer. Practitioner 210:820-5, 1972.

22. Zhou H and Jiao D: 312 cases of gastric and duodenal ulcer
bleeding treated with 3 kinds of alcoholic extract rhubarb tablets.
Chung Hsi I Chieh Ho Tsa Chih 10:150-1, 131-2, 1990.

23. Beil W, Birkholz and Sewing KF: Effects of flavonoids on parietal
cell acid secretion, gastric mucosal prostaglandin production and
Helicobacter pylori growth. Arzneim Forsch 45:697-700, 1995."

Dr. Murray Online: DGL: A SPECIAL LICORICE EXTRACT FOR PEPTIC ULCERS
http://www.doctormurray.com/articles/ulcer.htm

Other DGL references:

"Lancet. 1982 Oct 9;2(8302):817. 

Deglycyrrhizinated liquorice for peptic ulcer.

Glick L."

PubMed Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6126680

"J Pharm Pharmacol. 1980 Feb;32(2):151. Related Articles, Links  

Aspirin-induced gastric mucosal damage in rats: cimetidine and
deglycyrrhizinated liquorice together give greater protection than low
doses of either drug alone.

Bennett A, Clark-Wibberley T, Stamford IF, Wright JE."

PubMed Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6103045

"J Assoc Physicians India. 1978 Sep;26(9):811-4. Related Articles, Links  

Deglycyrrhizinated liquorice in the treatment of chronic duodenal ulcer.

Balakrishnan V, Pillai MV, Raveendran PM, Nair CS."

PubMed Abstract
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=370079

======================================================================

My Google search strategy:

Google Web Search: "cabbage juice" ulcers
://www.google.com/search?hl=en&q=%22cabbage+juice%22+ulcers

Google Web Search: "deglycyrrhizinated licorice" OR dgl ulcers
://www.google.com/search?hl=en&q=%22deglycyrrhizinated+licorice%22+OR+dgl+ulcers

I hope this is helpful. If anything is unclear or incomplete, please
request clarification; I'll be glad to offer further assistance before
you rate my answer.

Best regards,
pinkfreud
mades32388-ga rated this answer:5 out of 5 stars and gave an additional tip of: $10.00
Thanks, that was very informative & everything I was looking for!!!

Comments  
Subject: Re: Cabbage Juice for Ulcers
From: stressedmum-ga on 09 Mar 2005 22:05 PST
 
... and while we're talking about the ulcer-healing properties of some
everday foods such as cabbage and licorice, here's some extra
information about the efficacy of Manuka Honey. Whether the ulcer is
peptic or skin, it is well worth considering honey. Dr Peter Molan of
Waikato University in New Zealand has done extensive research and was
very helpful when I contacted him to get further information regarding
my diabetic mother's leg ulcers in 2000. After 5 years of intensive,
daily nursing care and thousands of dollars in medications and
dressings, including 4 long term hospital stays for ulcer treatment,
just 6 months of daily honey dressings (administered by the Royal
District Nurses and requiring morphine half an hour before to
alleviate the pain of application) saw not only a miraculous healing
of her 'horror-movie' wounds, but also saw a stabilisation of her
blood sugar levels, resulting in her no longer requiring medication
for diabetes. I know it's not what you asked for, but I have offered
it in the belief that it's relevant to your question.

Thank you for an interesting question on a topic very close to my heart!

Stressedmum

http://www.worldwidewounds.com/2001/november/Molan/honey-as-topical-agent.html
Subject: Re: Cabbage Juice for Ulcers
From: pinkfreud-ga on 10 Mar 2005 10:23 PST
 
Thank you very much for the five-star rating and the generous tip! 

~pinkfreud

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