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Subject:
G proteins
Category: Science Asked by: val1-ga List Price: $2.00 |
Posted:
30 Mar 2005 10:23 PST
Expires: 29 Apr 2005 11:23 PDT Question ID: 502731 |
Are all G proteins ADP ribosylated? |
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There is no answer at this time. |
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Subject:
Re: G proteins
From: xarqi-ga on 30 Mar 2005 14:05 PST |
In biology, there is at least one exception for every rule, so right off the bat I can say "No" with great confidence. My knowledge of G proteins is a bit rusty, so I did a very quick survey and reached the opinion that most (but not all) G proteins are NOT ADP-ribosylated under normal circumstances, but most (or even all) MAY be ADP-ribosylated by toxins such as pertussis and cholera toxin. |
Subject:
Re: G proteins
From: zn833-ga on 01 Apr 2005 10:48 PST |
I agree with xarqi's comment, but want to clarify that cholera, pertussis, and many other's are specific in which G protein they ribosylate. For example, Cholera only ribosylates Gsa. If you are looking for G-proteins that don't get ribosylated I would start with those in the eye (Go I believe) that associate with rhodopsin |
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