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Subject:
Pharmacokinetic information on dopamine agonists (half-life request)
Category: Science Asked by: drchopsuey-ga List Price: $8.00 |
Posted:
20 Apr 2005 19:08 PDT
Expires: 20 May 2005 19:08 PDT Question ID: 512075 |
I am having a difficult time locating information on two dopamine agonists: SKF 81297 (D1-like agonist) and quinpirole (D2-like agonist). What is the half-life for these drugs in rats (specifically of the Wistar strain)? And any other pharmacokinetic information (or where I can find such information) would be greatly appreciated. |
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There is no answer at this time. |
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Subject:
Re: Pharmacokinetic information on dopamine agonists (half-life request)
From: linezolid-ga on 25 Apr 2005 06:49 PDT |
I don't think you're going to find a lot of information about the pharmacokinetics of these drugs: they are not common, and doing such studies would likely be difficult, expensive, and not terribly useful. If you are interested in their effects, however, you can go to http://www.pubmed.org and do a MeSH search for "quinpirole" and "SKF 81297". I took a quick look through the results, and didn't see any pharmacokinetic studies, though. Cheers |
Subject:
Re: Pharmacokinetic information on dopamine agonists (half-life request)
From: drchopsuey-ga on 27 Apr 2005 17:42 PDT |
Dear Linezolid: Yeah, I've gone through Pubmed, Medline and ScienceDirect as well as others. I use these two agonists in my thesis. It would be really good to find the info. but no one knows. I've even tried contacting Sigma (the company that I purchased from), Eli-Lilly and others! I guess I can try to convince my committee it is not too important to know this info.... Thank you for the comment! |
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