To whom it concerns,
        I am am indidvidual who is about to begin some research in the
science field of cellular and molecular biology over the summer.
Before I get started, I wanted to gain a very good foundation on the
knowledge of this field. So i have been doing independent work and
have come across some questions that I have not been able to
understand. The following question is one that I have had extreme
problem in solving. I need to thoroughly have a good explanation of
this problem. The information that I have found on this has not helped
me answer this question so i turn to you to help me out. I thank you
very much of your help and your time. So here is the question: This
question deals with overexpression in normal and cancer cells. So.
here it is:

Over-expression of Myc is a common feature of many types of cancer
cells, contributing to their excessive cell growth and proliferation.
By contrast, when Myc is hyperactivated in most normal cells, the
result is not excessive proliferation but cell-cycle arrest or
apoptosis. How is it that over-expression of Myc can have such
different outcomes in normal cells and cancer cells?

Many transformed (i.e., cancerous) cell lines can be "detransformed"
if mixed in culture with normal parental cells; that is, they no
longer exhibit their cancerous
phenotype or behavior. For instance, when non-transformed C3H10 cells
are placed together with a transformed offspring cell line, MC4AB10,
the latter become normal in phenotype. Describe experiments to
determine if this effect results from cell-to-cell contact between the
two types of cells or from the release of a hormone-like factor by the
non-transformed cells.

I need a lot fo assistance with this problem as it requires answers
that are very thorough and complete. Any help would be very
appreciated and it would help me come closer to getting my research
started. Thanks a lot.

This sounds more like you have two weeks to hand in these questions.
It is hard to see what research project would include both Caulobacter
and cancer cells

i must do this background work before being assigned a research project

I'm with mikewa-ga. This and the last question by tellanish-ga makes
me think someone has a take home final.

I'm going to go out on a limb here, and say, if you can't suggest a
way to test if it is cell-cell contact, or a soluble factor, that
research might not be a good idea.

I'm going to give you clues to help answer these "questions" mostly
because I enjoy tourturing people - but more importantly, because you
will benifit more from figuring it out yourself than having someone
else do it for you.
For the first part, consider the following:
c-myc - what does it do in a normal cell? what does it respond to?
what does it activate? what is the effect on the cell cycle in normal
cells? what happens when you over express it in normal cells?
p53 - what is its role in a normal cell? how might the overexpression
of myc drive p53 related apoptosis?
Remember, in cancer cells, there is rarely just one mutation - keep
this in mind when trying to answer the question.

As for the second question...
If a hormone-like factor is released how might you know? What happens
if you culture CHO cells and then use the medium they were cultured in
on the transformed cell line? If they are normal what does this say?
If abnormal still, then....what are some of the important cell-cell
contact molecules? What proteins are membrane bound and expressed in
the CHO cells? What happens if you knock out these components?

In addition, giving you the benifit of the doubt that this is not for
an exam, really take the time to pick up a  few good bio textbooks,
see the ones I suggested in an answer to your other question. If this
is for an exam, then may God have mercy on your cheating soul.  You
are only hurting yourself - and if you want to be part of the
scientific community, this isn't the way to do it.  Learn to think
critically or perish.

Sermon ends here.

Patrick