Greetings,
Based upon the following mechanism of action listed for the herb
"rhodiola rosea", would you think it is safe to take with a selective
serotonin reuptake inhibitor, and what would the neurochemical effects
be? Any interpretation and opinion is welcome.
MECHANISM OF ACTION
Rhodiola exerts cardioprotective and central nervous system stimulant
effects by altering the levels of biogenic monoamines such as
dopamine, nor-epinephrine, and serotonin in the brain. This modulation
is believed to result from inhibition of the enzymes monoamine oxidase
and catechol-o-methyl transferase that are responsible for monoamine
degradation (10). Rhodiola also aids the transport of
neurotransmitters in the brain (10). It is thought to help the body
adapt to stressors by preventing release of catecholamine and increase
in cyclic AMP levels in the myocardium, and by depleting adrenal
catecholamine (11). |