Google Answers Logo
View Question
 
Q: Folic Acid ( Answered 5 out of 5 stars,   1 Comment )
Question  
Subject: Folic Acid
Category: Science > Agriculture and Farming
Asked by: justadream-ga
List Price: $10.00
Posted: 25 Aug 2005 18:50 PDT
Expires: 24 Sep 2005 18:50 PDT
Question ID: 560605
Folic Acid Used To Fortify Grain Based Foods Is Obtained How????
I Need To Know.There Is A 50$ Tip If You Provide A Clear Answer.
I Searched The Net For A Long Painfull Time Limit,But Nothing Came Up.

Request for Question Clarification by hummer-ga on 26 Aug 2005 06:31 PDT
Hi justadream,

Do you need to know where you can purchase enough Folic Acid for home
baking or in larger quantities?

Thanks,
hummer
Answer  
Subject: Re: Folic Acid
Answered By: hummer-ga on 26 Aug 2005 10:20 PDT
Rated:5 out of 5 stars
 
Hi  justadream,

Here you go - the first link is for wholesale bulk purchases and the
second and third links are for smaller quantities.

>>> 25kg

Nutrimart.com
Wholesale Bulk Raw Materials For Manufacturing Process Only
Folic Acid  	97%-102%  	USP24/BP98  	25 Kgs
Folic Acid 10% 	10% min. 	USP24/BP98 	25 Kgs
3604 Hawkwood Road Diamond Bar, CA. 91765 U.S.A
Fax: (909)861-0588 U.S.A. 24 Hours
Phone: (909)396-6530  Monday - Friday 10AM-5PM Pacific Standard Time
E-mail Sale@nutrimart.com  
(Send A E-mail for Price Quote )
http://www.nutrimart.com/bulkraw.htm

>>> 30g - 120g

Life Extension
 30g: members: $12.00; nonmembers: $16.00
120g: members: $41.24; nonmembers: $55.00
Life Extension Foundation
P.O. Box 229120
Hollywood, FL 33022, USA
Toll Free Phone (Orders): 800-544-4440
Fax 954-761-9199
http://www.lef.org/newshop/items/item00148.html

Health Marketplace.com
Life Extension: 30g: $14.95
6355 Tamar Drive
Columbia, MD 21045
Order Toll Free (800)-616-5411
Fax-(410)-730-4662
customerservice@health-marketplace.com 
http://www.health-marketplace.com/Folic-Acid.htm


Additional Links of Interest:

Wikipedia has an exellent article on Folic Acid:

Wikipedia: Folic acid
http://en.wikipedia.org/wiki/Folic_acid

The Folic-Acid Factor
http://www.foodproductdesign.com/archive/2003/0403INI.html

FOLIC ACID FORTIFICATION
http://www.cfsan.fda.gov/~dms/wh-folic.html

How Folate Can Help Prevent Birth Defects
http://vm.cfsan.fda.gov/~dms/fdafolic.html

DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
21 CFR Parts 136, 137, and 139
Docket No. 91N-100S
RIN 0910-AA19
Food Standards: Amendment of Standards of Identity For Enriched
Grain Products to Require Addition of Folic Acid
AGENCY: Food and Drug Administration, HHS.
ACTION: Final rule.
http://www.cfsan.fda.gov/~lrd/fr96305b.html

DEPARTMENT OF HEALTH AND HUMAN SERVICES
21 CFR Part 172
Docket No. 91N-100F
Food Additives Permitted for Direct Addition to Food for Human
Consumption; Folic Acid (Folacin)
AGENCY: Food and Drug Administration, HHS.
ACTION: Final rule.
http://www.cfsan.fda.gov/~lrd/fr96305c.html

Alfa Chem
1-800-375-6869
2 Harbor Way . Kings Point, NY 11024-2117
T: (516) 504-0059 . F:(516) 504-0039
E-mail: alfachem1@aol.com 
General Product List: FOLIC ACID [59-30-3]
http://www.alfachem1.com/

I hope this is what you've been looking for. If not, or if you have
any questions, please post a clarification request and wait for me to
respond before closing/rating my answer.

Thank you,
hummer

Google Search Terms Used:

dicalcium phosphate folic acid powder wholesale
maltodextrin folic acid powder wholesale
maltodextrin folic acid powder 1 kg
maltodextrin folic acid powder bulk
folic acid suppliers
folic acid food additive
Folacin
Pteroyl Glutamic Acid
folate

Request for Answer Clarification by justadream-ga on 28 Aug 2005 12:53 PDT
Hello Hummer-Ga

You took my question abit wrong,but it was my fault.I didnt specify
clearly enough,but the request was regarding how is the folic acid in
the fortified foods and grains made,from what is it obtained (I.e.
vegetables,fruits,animal derived,etc) and perhaps the process of how
they make it.

Clarification of Answer by hummer-ga on 28 Aug 2005 14:29 PDT
Hi justadream,

I'm sorry for the misunderstanding. The Folic acid which is added to
grain products is the synthetic form.

"Synthetic (manufactured) folic acid is added to grain products,
including flour, rice, pasta, cornmeal, bread and cereals. These foods
are considered ?fortified? with folic acid."
http://www.marchofdimes.com/professionals/14332_1151.asp 

"The synthetic form of folate in fortified foods is 1.7 times greater
bioavailability than forms found naturally in food."
http://www.feinberg.northwestern.edu/nutrition/factsheets/folate.html

As it happens, the Wikipedia link I gives you contains all of its properties.

Folic acid
http://en.wikipedia.org/wiki/Folate

Here are some more links which should give you a pretty good idea what
Folic Acid is.

Folic Acid [view three images]
Folic acid is a water-soluble B complex vitamin that is required for
animal metabolism. Sometimes alternatively known as vitamin B9, the
substance can be found in a wide variety of food items, such as green,
leafy vegetables, brewer?s yeast, soybeans, wheat, and liver."
"Folic acid was initially isolated from spinach leaves, an event that
resulted in its common name, which is derived from the Latin word
folium, meaning ?leaf.? The vitamin was first produced synthetically
in 1945, and since that time has been included in a wide array of
supplements and many fortified foods, such as cereals."
http://www.olympusmicro.com/galleries/polarizedlight/pages/folicacidsmall.html

Folic Acid: Water Soluable
"Folic acid is a conjugated molecule consisting of a pteridine ring
structure linked to para-aminobenzoic acid (PABA) that forms pteroic
acid. Folic acid itself is then generated through the conjugation of
glutamic acid residues to pteroic acid. Folic acid is obtained
primarily from yeasts and leafy vegetables as well as animal liver.
Animal cannot synthesize PABA nor attach glutamate residues to pteroic
acid, thus, requiring folate intake in the diet." [see graphic]
http://isu.indstate.edu/mwking/vitamins.html#folic

Folates are a class of naturally occurring compounds (polyglutamates)
with the vitamin properties of folic acid. The synthetic forms of
folic acid contain only monoglutamates. Polyglutamates must be
converted to absorbable monoglutamates in the upper small intestine.
(7) Synthetic folic acid supplements, therefore, provide better
bioavailability than folate from natural source, an important concept
when determining the best way to deliver adequate amounts of folic
acid to the target population (see below). "
http://www.obfocus.com/nutrition/nutrition1.htm

Although folate (the natural form) and folic acid (the synthetic form)
are very similar in structure, folate is not as stable as folic acid -
it is more easily damaged by cooking and processing. Also, food
folates need to be broken down in the digestive system before the body
can absorb them. This means that folic acid is absorbed more
efficiently than the natural form of the vitamin."
http://www.nutrition.org.uk/upload/Consumer%20booklet%20folate%20final.pdf

Sorry to say, I don't believe a description of the manufacturing
process is available online.

I hope we are finally on the same wavelength!

Regards,
hummer

Request for Answer Clarification by justadream-ga on 02 Sep 2005 15:25 PDT
Hello Hummer,were getting close.

You mentioned in regard to folic acid being possibly derived from animal liver.
I need some information on that,for example,what kind of animal,and
mainly in which kind of products.Another one is if vegetable derived
folic acid is used in enriching grain products like cooking rice,or is
animal liver used instead?
And what about the "Acid" in the Folic Acid,does that mean it has some
alcoholic acidity in it? is folic acid fermented somehow? This might
be alot of work for you,but Im giving you 50$ as a tip whenever the
answer is sufficient.
TY

Clarification of Answer by hummer-ga on 02 Sep 2005 17:27 PDT
Hi justadream. I'll see what else I can come up with and let you know
as soon as possible. I trust that you're not in a rush. Regards,
hummer

Clarification of Answer by hummer-ga on 03 Sep 2005 18:16 PDT
Hi TY,   

1)  You mentioned in regard to folic acid being possibly derived from
animal liver. I need some information on that,for example,what kind of
animal,and mainly in which kind of products.

Liver is a very good source but I don't believe it is being used to
enrich our food supply. Perhaps in some supplements, but not in grain
products. I haven't a clue what kind of animal, I doubt there would be
just one animal but several.

WATER-SOLUBLE VITAMINS
"With the exception of vitamin C (ascorbic acid), water-soluble
vitamins belong mainly to what has been termed the B complex of
vitamins. The better-known B vitamins are thiamine (B-1), riboflavin
(B-2), niacin (B-3), pyridoxine (B-6), pantothenic acid, lecithin,
choline, inositol, and para-aminobenzoic acid (PABA). Two other
members are folic acid and cyanocobalamin (F-12). Yeast and liver are
natural sources of most of these vitamins."
http://hepatitis-c.de/mainvit.htm 

A comprehensive list of ingredients derived from animals
Ingredients that may be derived from animals:
Folic Acid
http://www.fortunecity.com/greenfield/shell/5/ingred.htm

Vitamins Sources Most Frequently Found in Supplements
Folic Acid  
Natural:	   	
Vegetarian Yeast, Brewer?s Yeast, Blackstrap Molasses, Wheat Grass, Nuts 
Synthetic:	  	
Pteroylglutamic Acid
http://iweightloss.com/supplement_labels.htm

2) Another one is if vegetable derived folic acid is used in enriching
grain products like cooking rice,or is animal liver used instead?

Neither, Folic Acid (synthetic form) is added to grain products
because it is less easily damaged by cooking and and it is more more
readily available in the digestive tract.

"Although folate (the natural form) and folic acid (the synthetic form)
are very similar in structure, folate is not as stable as folic acid -
it is more easily damaged by cooking and processing. Also, food
folates need to be broken down in the digestive system before the body
can absorb them. This means that folic acid is absorbed more
efficiently than the natural form of the vitamin."
http://www.nutrition.org.uk/upload/Consumer%20booklet%20folate%20final.pdf

"Folate is a water-soluble B vitamin that occurs naturally in food.
Folic acid is the synthetic form of folate that is found in
supplements and added to fortified foods [1].
In 1996, the Food and Drug Administration (FDA) published regulations
requiring the addition of folic acid to enriched breads, cereals,
flours, corn meals, pastas, rice, and other grain products [6-9].
Since cereals and grains are widely consumed in the U.S., these
products have become a very important contributor of folic acid to the
American diet. The following table suggests a variety of dietary
sources of folate."
Table 1: Selected Food Sources of Folate and Folic Acid [5]
* Items marked with an asterisk (*) are fortified with folic acid as
part of the Folate Fortification Program.
"However, the folic acid fortification program, which was initiated in
1998, has increased folic acid content of commonly eaten foods such as
cereals and grains, and as a result most diets in the United States
(US) now provide recommended amounts of folate equivalents [14]."
http://ods.od.nih.gov/factsheets/folate.asp

Here's a pretty good history -

Epi in Action
http://www.whsc.emory.edu/_pubs/ph/spring01/epi.html

3) And what about the "Acid" in the Folic Acid, does that mean it has
some alcoholic acidity in it? is folic acid fermented somehow?

I would think that the word "acid" comes from "pteroic acid", a
constituent of folic acid.

"pteroic acid (pte·ro·ic ac·id) (t[schwa]-ro˘ik)  a constituent of
folic acid consisting of p-aminobenzoic acid linked to a substituted
pteridine by a methylene bridge."
http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_p_41zPzhtm#1088412

Yes, it is produced by fermentation.

Fabricating folic acid
"Manufacturers create folic acid via numerous fermentation and
purification steps to meet U.S. Pharmacopoeia (USP) or European
Pharmacopoeia (EP) monograph requirements. Once it is fermented and
purified, folic acid becomes a fine chemical, in the form of a fluffy
yellow-orange powder. It is water soluble and very stable in
low-moisture heat. Acidity is the most vexing problem for folic acid
as it degrades easily in low-pH products (below pH 5)."
http://www.foodproductdesign.com/archive/2003/0403INI.html

# Initial Source: Yeast via microbiological fermentation process.
# Processing: Laboratory synthesized
https://www.immunesupport.com/shop/product.cfm/product__code/PH79/tab/Label

Fermentation Biotechnology
edited by Badal C. Saha
2003 ? 287 pages ? $134.00 + shipping
Metabolic Engineering of Folic Acid Production
http://www.chipsbooks.com/fermbiot.htm

Regards,
hummer
justadream-ga rated this answer:5 out of 5 stars and gave an additional tip of: $50.00
Wonderfull work Hummer,Ill have more questions later.Get ready.

Comments  
Subject: Re: Folic Acid
From: hummer-ga on 11 Sep 2005 09:42 PDT
 
Thank you very much, justadream, I'm happy you are happy and I'm glad
to hear we finally managed to get on the same wavelength!  Sincerely,
hummer

Important Disclaimer: Answers and comments provided on Google Answers are general information, and are not intended to substitute for informed professional medical, psychiatric, psychological, tax, legal, investment, accounting, or other professional advice. Google does not endorse, and expressly disclaims liability for any product, manufacturer, distributor, service or service provider mentioned or any opinion expressed in answers or comments. Please read carefully the Google Answers Terms of Service.

If you feel that you have found inappropriate content, please let us know by emailing us at answers-support@google.com with the question ID listed above. Thank you.
Search Google Answers for
Google Answers  


Google Home - Answers FAQ - Terms of Service - Privacy Policy