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Q: About Genes ( Answered,   2 Comments )
Question  
Subject: About Genes
Category: Science > Biology
Asked by: evergreen12-ga
List Price: $2.00
Posted: 27 Aug 2005 08:58 PDT
Expires: 26 Sep 2005 08:58 PDT
Question ID: 561132
The genomic address (locus) for a gene that produces premature
baldness in males is 19s6.7. Which of the following chromosomes
contains this gene?
Answer  
Subject: Re: About Genes
Answered By: nenna-ga on 27 Aug 2005 19:57 PDT
 
Good evening evergreen12  and thank you for your question.

Though I am not sure about the genomic address, according to the
Anti-Aging Library, the chromosome which contains the gene related to
male-pattern baldness is the X chromosome.

"Researchers in Germany have found that variations in a gene related
to male sex hormones may be at the root of male-pattern baldness, the
most common form of hair loss. The culprit is the androgen receptor
gene, and it dwells on the X chromosome, which all men inherit from
their mothers...The androgen receptor gene helps govern the workings
of male sex hormones (androgens), such as testosterone. Though these
hormones promote the growth of body and facial hair, on the scalp
excess androgens may cause hair loss."

Source: Genes in male-pattern baldness identified
( http://www.worldhealth.net/p/genes-in-male-pattern-baldness-identified-2005-06-13.html
)

The Androgen Receptor Gene - Chromosomal location: Xq11-12
(pericentromeric region).

Source:  The Androgen Receptor Gene - 'One gene - two syndromes'
) http://www.ich.ucl.ac.uk/cmgs/argene98.htm )

I hope this answers your question.  If you would like clarification
before rating my answer, please do not hesitate to ask!

Nenna-GA
Google Researcher
Comments  
Subject: Re: About Genes
From: dops-ga on 07 Sep 2005 13:20 PDT
 
Based upon the info given "19s6.7" it is unlikely that the gene your
interested in is on the X chromosome. Instead it probably on the 19th
chromosome. For designating a genetic locus the first numbers (in this
case 19) designates chromosome number, the letter indicates the arm
and the second numbers indicate position. The problem is that there is
no "S" arm only "P" or "Q." Where'd you find the 19s6.7 designation?
What kind of map was it?
Subject: Re: About Genes
From: undone-ga on 14 Sep 2005 06:27 PDT
 
I am quite sure you will find the expression of male patturn bladness
on the X gene since it follows morgans sex linked inheritance
patturns.  This means that it is much more likely for a male to
inherit the condition than a female.  This shys away from the usual
mendalin genetic inheritance patturns which unless the loci are linked
have predictable ratios and are not effected by gender.

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