|
|
Subject:
Microbiology
Category: Miscellaneous Asked by: mashhour-ga List Price: $5.00 |
Posted:
19 Aug 2002 01:49 PDT
Expires: 18 Sep 2002 01:49 PDT Question ID: 56131 |
CHoose the single most appropriate from those listed below and place it in the left or right the question. (A) CH2 region of molecule (B) CH3 region of molecule (D) CH4 region of molecule (E) None of these 1- The Clq binding site of IgG 2- The Clq binding of IgM 3- The Clq binding of IgD 4- The Clq binding of IgE 5- Neutrophil, monocyte, platelet, and lymphocyte binding site IgG 6- Lymphocyte binding site of IgM 7- J chain binding site of IgG 8- Neutrophil binding site if IgM 9- Antigenic combining site of IgG Choose the single most appropriate answer from those listed below and place it. (A) Allergy capable of transient passive transfer from one person to anothe by serum. (B) Allergy capable of passive transfer by mean of cell only. (C) Both (D) neither 1- Systemic anaphylaxis 2- Tuberculin sensitivity 3- Food Allergy 4- Contact dermatitis 5- Poison Ivy |
|
Subject:
Re: Microbiology
Answered By: nealc-ga on 20 Aug 2002 08:41 PDT Rated: |
After conferring with the resident immunologist in my department we came up with the following answers. (A) CH2 region of molecule (B) CH3 region of molecule (D) CH4 region of molecule (E) None of these 1- The Clq binding site of IgG (A- CH2) 2- The Clq binding of IgM (B- CH3) 3- The Clq binding of IgD (E- none of these) 4- The Clq binding of IgE (E- none of these) 5- Neutrophil, monocyte, platelet, and lymphocyte binding site IgG (A- CH2) 6- Lymphocyte binding site of IgM (If this is monomeric IgM with the transmembrane portion of IgM linked to the surface of a naïve B cell then the answer would be D- CH4, However, if you what the portion of IgM bound to an Fc receptor on a lymphocyte then the answer would be B- CH3) 7- J chain binding site of IgG (E- none of these) 8- Neutrophil binding site of IgM (E- none of these) 9- Antigenic combining site of IgG (E- none of these) Choose the single most appropriate answer from those listed below and place it. (A) Allergy capable of transient passive transfer from one person to another by serum. (B) Allergy capable of passive transfer by means of cells only. (C) Both (D) Neither 1- Systemic anaphylaxis (A)- requires allergen, IgE, and mast cells. If the recipient has sufficient mast cells then passively transferred IgE and allergen will cause mast cell degranulation. 2- Tuberculin sensitivity (B) 3- Food Allergy (A)- same reason as 1 above. 4- Contact dermatitis (If type IV hypersensitivity then it is (B) if type I hypersensitivity then (A)) 5- Poison Ivy (B) A text that might be of help for other questions you may have would be Immunology, 6th edition, by Roitt, Brostoff, and Male, Mosby press, 2001. Hope that helps. Nealc-ga |
mashhour-ga
rated this answer:
In the first Questions, I think the number 1,5 and 6 are wrong |
|
Subject:
Re: Microbiology
From: nealc-ga on 22 Aug 2002 07:40 PDT |
Actually the answer to question 1 of the first question set is correct. See the following websites: http://www.xs4all.nl/~ednieuw/IgGsubclasses/subkl24.htm http://medweb.bham.ac.uk/immunityinfection/research/RoyJefferis/croatia/croatia.html The second website references journal articles that demonstrated the glycosylation of the CH2 site is important for Fc receptor binding to IgG as well as C1q. |
Subject:
Re: Microbiology
From: nealc-ga on 22 Aug 2002 07:49 PDT |
With respect to C1q binding to IgM the Roitt textbook I referred to in our answer states on page 59 that,"IgM is very efficient at complement activation as it contains potentially 10 C1q binding sites in its CH3 domains." Furthermore, the same page of Roitt states that,"the six heads of C1q each contain a binding site for a domain in IgG (CH2)." |
Subject:
Re: Microbiology
From: mashhour-ga on 22 Aug 2002 09:49 PDT |
Sorry you are right not # one of the first Question, i think # 2,5, and 6 of the first Question are wrong |
If you feel that you have found inappropriate content, please let us know by emailing us at answers-support@google.com with the question ID listed above. Thank you. |
Search Google Answers for |
Google Home - Answers FAQ - Terms of Service - Privacy Policy |