I need the name of the ten top selling drugs in the US.  The name of
the drug, the drug company who distributes it, the annual net profit,
the percentage of sales.

Second, I need the top ten selling drugs in a mental health area such
as Bipolar, Psychosis, Depression, Altzhimers, Parkinson, Autism,
Anxiety.  Same breakdown.  Some of these drugs are: Depakote,
Tegretal, Risperdone or Risperdal, Mellerill, Zyprexa, Zoloft.

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Request for Question Clarification by rainbow-ga on 14 Oct 2005 01:50 PDT

Hi santabarbara,

Since these are two different questions, I suggest you separate and
post them individually, priced accordingly.

I can provide you with the following:

The World's Top-Selling Drugs (2003)
Name of the drug  
Purpose of the drug 
Maker  
Global Sales  
U.S. Sales  
Percentage Of Sales In U.S.  

Looking forward to your clarification.

Best regards,
Rainbow

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Clarification of Question by santabarbara-ga on 14 Oct 2005 02:08 PDT

I will keep it at 2 questions for $25.

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Request for Question Clarification by rainbow-ga on 14 Oct 2005 02:08 PDT

I have also found a list of the top 20 selling drugs in the United
States in 2003, their annual sales, what it treats and its
manufacturer.

Rainbow~

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Clarification of Question by santabarbara-ga on 14 Oct 2005 03:08 PDT

What is your question?

Hi santabarbara,

The following is the result of my research for the data you have
requested on best selling drugs:


A List of the Best-Selling Drugs in the U.S.
(As appeared in the online version of the New York Times 9/30/04)

The top selling drugs in the United States in 2003, their annual
sales, what it treats and its manufacturer. The 2003 data is the most
recent audited figures available.

DRUG                ANNUAL SALES          TREATS         MANUFACTURER
Lipitor             $6.8 billion        cholesterol      Pfizer Inc. 
Zocor               $4.4 billion        cholesterol      Merck & Co. 
Prevacid            $4.0 billion        heartburn        TAP Pharma
Procrit             $3.3 billion        anemia           Johnson & Johnson 
Zyprexa             $3.2 billion        mental illness   Eli Lilly & Co. 
Epogen              $3.1 billion        anemia           Amgen
Nexium              $3.1 billion        heartburn        Merck & Co. 
Zoloft              $2.9 billion        depression       Pfizer Inc. 
Celebrex            $2.6 billion        arthritis        Pfizer Inc. 
Neurontin           $2.4 billion        epilepsy         Pfizer Inc. 
Advair Diskus       $2.3 billion        asthma           GlaxoSmithKline PLC 
Plavix              $2.2 billion        blood clots      Bristol-Myers Squibb  
Norvasc             $2.2 billion        hypertension     Pfizer Inc. 
Effexor XR          $2.1 billion        depression       Wyeth 
Pravachol           $2.0 billion        cholesterol      Bristol-Myers Squibb 
Risperdal           $2.0 billion        mental illness   Johnson & Johnson 
Oxycontin           $1.9 billion        pain             Perdue Pharma 
Fosamax             $1.8 billion        osteoporosis     Merck & Co. 
Protonix            $1.8 billion        gastrointestinal Wyeth 
Vioxx               $1.8 billion        arthritis        Merck & Co. 

Friedman & Simon
http://www.friedmanandsimon.com/CM/Custom/Custom15.asp

========================================

Top 200 Drugs for 2004 by U.S. Sales

"The information contained in this report was derived using NDCHealth
proprietary methodologies and is based on prescription data and
wholesale acquisition cost (WAC) prices for retail, mail order,
clinics, hospitals, long-term care and home health care organizations
and other non-retail channels."

Source: NDCHealth, NDC PHAST, 3/2005
http://www.ndchealth.com/press_center/uspharmaIndustryData/ndchealthtop2002004sales.htm

========================================

TOP 500 PRESCRIPTION DRUGS BY SALES (2004)

PharmaLive
http://www.pharmalive.com/special_reports/sample.cfm?reportID=191

========================================

TOP 200 BRAND-NAME DRUGS BY RETAIL DOLLARS IN 2004

Drug Topics
http://www.drugtopics.com/drugtopics/data/articlestandard/drugtopics/112005/150644/article.pdf

========================================

The World's Top-Selling Drugs
Forbes
http://www.forbes.com/technology/2004/03/16/cx_mh_0316bestselling.html

========================================

Top 10 Selling Prescription Drugs in the Mental Health Segment (2004)

PRODUCT             CORPORATION              TOTAL RETAIL DOLLARS(add 000) 
Zoloft                Pfizer                       2,622,801
Effexor               Wyeth                        2,281,014
Zyprexa               Eli Lilly                    1,881,354
Lexapro               Forest Labs                  1,551,230
Risperdal             Johnson & Johnson            1,436,891
Seroquel              AstraZeneca                  1,378,038
Wellbutrin            GlaxoSmithKline                948,683
Celexa                Forest Labs                    856,665
Paxil                 GlaxoSmithKline                824,433
Abilify               Bristol-Myers Squibb           747,400


Source: I manually compiled this list by using various websites. Some of which are:

Drug Topics
http://www.drugtopics.com/drugtopics/data/articlestandard/drugtopics/112005/150644/article.pdf

Rx List
http://www.rxlist.com/cgi/rxlist.cgi?drug=

PharmaLive
http://www.pharmalive.com/special_reports/sample.cfm?reportID=191
    
 
Search criteria:
"ten top selling" drugs US
"top OR best selling drugs" US 2005
"top * prescription drugs"
"top OR best selling" drugs "mental health" 
best-selling "mental health drugs"

I hope the information provided is helpful.

Best regards,
Rainbow

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Request for Answer Clarification by santabarbara-ga on 14 Oct 2005 14:12 PDT

Prozac aka Fluoxetine is not on the list?

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Clarification of Answer by rainbow-ga on 14 Oct 2005 23:56 PDT

Thank you for the rating and generous tip. 

Prozac (aka Fluoxetine) is number 156 on the list of the top 200
brand-name drugs by retail dollars in 2004.

Best regards,
Rainbow

Very good answer. Thanks.

Not terribly suprising that fluoxetine has dropped from the list,
considering the newer SSRIs (ie Zoloft aka Sertraline) have lower
occurance and less severe side effects.

Furthmore, drugs such as buproprion (welbutrin) are making inroads
into territory formerly solidly locked up by the SSRIs.

Oh, as a side note, Fluox is off patent now, so perhaps this decreases
the percieved drug sale, due to multiple manufacturers (instead of
lily) distributing the drug - it still might be really highly used,
just not all sales coming from lily.

I think part of the popularity of buproprion is its use in nicotine
cessation in conjunction with the mood altering effects. There's a
pretty curious link between nicotine use and mental disorders. I'm not
sure if it's a statistically significant link, since I'm just
theorizing myself, but I think that compared to the general
population, people with major depressive disorder or dysthymia also
tend to use nicotine products at a higher rate. If you can treat both
simultaneously, bonus.

But also, there's no difference between Wellbutrin and Zyban. Zyban
costs more. And it's FDA approved for smoking cessation. Wellbutrin,
despite being an IDENTICAL substance, is not. A smart client and smart
doctor will save money by using buproprion instead of Zyban. It will
reflect as a Wellbutrin sale, however.