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Subject:
Carbamazepine Saliva Concentration Test Kit
Category: Health > Children Asked by: fdelaflor-ga List Price: $30.00 |
Posted:
26 Oct 2005 07:14 PDT
Expires: 25 Nov 2005 06:14 PST Question ID: 585109 |
It is well established that saliva antiepileptic drug (AED) concentrations strongly correlate with serum concentrations. In the October 2005 issue of ?Therapeutic Drug Monitoring? - the Official Journal of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology ? there is a paper published under the title ?Stability of Salivary Concentrations of the Newer Antiepileptic Drugs in the Postal System.? In this document, Doctors Jones, M; Ryan, M; Miles, M; Tang, P; Fakhoury, T; deGrauw, T; and Baumann, R conclude that: ?Saliva collection is painless and noninvasive, and untrained personnel can easily be taught the collection process. Remote patients could mail saliva samples to a laboratory for monitoring, and samples could be obtained in the immediate postictal state to provide a "real-time" concentration.? I am interested in measuring carbamazepine (CBZ) concentration in saliva for therapeutic drug monitoring (TDM) in a child which requires frequent analysis but hates been prick for blood samples more than eating broccoli! I am specifically seeking to find a few specialized lab supply firms that produce and sell saliva test kits for CBZ. As a reference, as this is an international question, so there no need for the kit to be FDA approved. |
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There is no answer at this time. |
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Subject:
Re: Carbamazepine Saliva Concentration Test Kit
From: frde-ga on 27 Oct 2005 07:03 PDT |
Get the child scanned for a 'benign brain tumour' Medics irresponsibly use Carbamazepine (Tegretol) for other problems than epilepsy - it is evil - I was once precribed it for a damaged nerve. The only other person I know who /had/ to use it died, and the autopsy showed a massive 'benign brain tumour' - supposedly a rare cause of epilepsy, but somehow I am very suspicious. |
Subject:
Re: Carbamazepine Saliva Concentration Test Kit
From: fdelaflor-ga on 29 Oct 2005 09:15 PDT |
Frde-ga, thank you for your frank comment and suggestion. Fortunately, all brain scans are negative including magnetic resonance imaging (MRI) and computerized tomography (CT.) In my question, carbamazepine is used to control seizures in a childhood epilepsy diagnostics. |
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