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Q: history of the OTC drug GUAIFENISEN ( Answered 5 out of 5 stars,   1 Comment )
Question  
Subject: history of the OTC drug GUAIFENISEN
Category: Health > Medicine
Asked by: timespacette-ga
List Price: $5.00
Posted: 26 Oct 2005 15:45 PDT
Expires: 25 Nov 2005 14:45 PST
Question ID: 585360
Can someone out there give a layperson's account of the history of guaifenisen?  

Was it a plant derivitive originally?   Or is it still?   If so, what plant?
Answer  
Subject: Re: history of the OTC drug GUAIFENISEN
Answered By: tlspiegel-ga on 26 Oct 2005 16:23 PDT
Rated:5 out of 5 stars
 
Hi timespacette,

Thank you for your question.  


Treating Fibromyalgia (cached page)
http://66.102.7.104/search?q=cache:koTYekXkCDUJ:www.alifemassage.com/december%2520archive.htm+guaicum+guaifenesin+extract&hl=en

"In 1530; in it's original form, a tree bark extract called guaicum,
was used for rheumatism. A paper written in 1928 showed it's value for
easing growing pains and Several other symptoms that are now
recognized as fibromyalgia. Guaicum was later purified to guaiacolate;
now synthesized and named Guaifenesin, and pressed into tablet form."

=========

Section II - Guaifenesin 
http://www.cfs-recovery.org/guaifenesin.htm

"In the 1500s, the guaicum plant was discovered and it was found to be
useful in treating "rheumatism".  As recently as 1920, a study was
published showing guaifenesin extracted from that plant to be an
effective treatment.

=========

Voxau.com
http://www.voxau.com/fib/fibro/51gufaq.htm

"The drug is extremely safe and was even used in 1928 as "Guaicum"
(extract of a tree bark) by some GP who reported its use for children
with several symptoms and "growing pains."

=========

Botanical.com
http://botanical.com/site/column_poudhia/publish/journal.cgi?folder=journal&next=1459

"From the traditional healers of Chhattisgarh Plains, I got new
information. The healers use the herb named Chobehyat for this
purpose. The scientific name of Chobehyat is Guaicum officinale. It is
a small tree introduced from the West Indies and is grown as an
ornamental. Gum Guaiacum or Guaiac resin, obtained either as natural
exudation from tree or by burning logs of wood, is used in medicine as
mild laxative and also for treating chronic rheumatism and gout. In
form of lozenges it is used for treating tonsillitis and pharyngitis
and also rheumatism. The traditional healers of Chhattisgarh Plains
use the gum internally to nullify the harmful effects of snake poison.
The gum is given in very small amount to the patients. The
disappearance of symptoms are considered as the time to stop the
medicine."

=========

FRLHT's Encyclopedia of Indian Medicinal Plants
http://66.102.7.104/search?q=cache:-Gfk14Z5LxgJ:www.medicinalplants.in/index.php%3Fplantid%3D3025%26calledFrom%3DVIEW_ALL_SPECIES%26sortBy%3DG%26gPAGE_NO%3D10%26gLOWER_LIMIT%3D180+Chobehyat&hl=en

Scroll to middle of Page for Plant Profile - Guaiacum officinale
(ZYGOPHYLLACEAE) and image

=========

keyword search:

Guaiacum or Guaiac resin herbal remedy
guaifenesin origins history
guaicum tree bark extract

=========


Best regards,
tlspiegel
timespacette-ga rated this answer:5 out of 5 stars
thanks so much

Comments  
Subject: Re: history of the OTC drug GUAIFENISEN
From: tlspiegel-ga on 26 Oct 2005 18:49 PDT
 
Hi timespacette,

Thank you for the 5 star rating and comment.  :)

Best regards,
tlspiegel

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