Hello Blucken-ga,
Thank you for your question.
The size of the transdermal patch in square cm. for the categories
listed in your question are the following:
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Pain Relief:
Lidoderm: 10 cm x 14 cm = 24 cm2
“Lidoderm® is composed of an adhesive material containing 5%
lidocaine that is applied to a non-woven polyester felt backing. When
applied to intact skin, Lidoderm® provides dermal analgesia by the
release of lidocaine from the patch into the epidermal and dermal
layers of the skin. The patch provides analgesic action, reducing pain
at the damaged and dysfunctional nerves, without the complete loss of
sensation or numbness. The size of the patch is 10 cm x 14 cm.”
http://www.lidoderm.com/2relpat.html
Emla: 10 cm2
“The contact surface area of the EMLA saturated disc is approximately
10 cm2.”
http://www.medsafe.govt.nz/Profs/Datasheet/e/Emlapatch.htm
DUROGESIC: 10 cm2 20 cm2 30 cm2 40cm2
Duragesic Patch Size(cm2) Fentanyl Content mg
Durogesic 25 10 2.5
Durogesic 50 20 5.0
Durogesic 75 30 7.5
Durogesic 100 40 10.0
http://www.medsafe.govt.nz/Profs/Datasheet/d/durogesictts.htm
Fentanyl: 10 cm2 20 cm2 30 cm2 40cm2
“The fentanyl patch is available in sizes of 10, 20, 30, or 40 cm2,
delivering 25, 50, 75, or 100 mcg of fentanyl per hour, respectively,
to the skin. The dose administered varies directly with the size of
the applied patch.”
http://www.mmhc.com/hhcc/articles/HHCC0012/sloan.html
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Hormone Replacement (HRT):
CLIMARA-50: 12.5 cm²
“12.5cm² patch containing 3.8mg of estradiol (equivalent to 3.9mg
estradiol hemihydrate) and releasing a nominal 50mcg per 24 hours”
CLIMARA-100: 25.0 cm²
“25.0cm² patch containing 7.6mg of estradiol (equivalent to 7.8mg
estradiol hemihydrate) and releasing a nominal 100mcg per 24 hours”
http://www.medsafe.govt.nz/Profs/Datasheet/c/Climaratransderm.htm
Estraderm: 11 cm2, 22 cm2, 33 cm2, 44 cm2,
Estraderm MX 25 0.75 mg oestradiol with an 11 cm2 release area.
Estraderm MX 50 1.5 mg oestradiol with a 22 cm2 release area.
Estraderm MX 75 2.25 mg oestradiol with a 33 cm2 release area.
Estraderm MX 100 3.0 mg oestradiol with a 44 cm2 release area.
http://www.appco.com.au/guide/Book%20Spread.pdf.
----------------------------------------------------------------------
Angina – Nitroglycerine:
Nitroglycerine: 3.3 cm2, 6.7 cm2, 13.3 cm2 and 20 cm2
“Transdermal Delivery System: This unit is designed to provide
continuous controlled release of nitroglycerin through intact skin.
the rate of release is linearly dependent upon the area of the applied
system; each cm2 of applied system delivers approximately 0.02 mg of
nitroglycerin per hour. Thus, 3.3, 6.7, 13.3 and 20 cm2 system
delivers approximately 0.1, 0.2. 0.4. and 0.6 mg of nitroglycerin per
hour, respectively.”
http://www.rxlist.com/cgi/generic/ntg.htm
Nitro-Dur: 5 cm2, 10 cm2, 15 cm2, 20 cm2, 30 cm2, and 40-cm2
“The NITRO-DUR (nitroglycerin) Transdermal Infusion System is a flat
unit designed to provide continuous controlled release of itroglycerin
through intact skin. The rate of release of nitroglycerin is linearly
dependent upon the area of the applied system; each cm2 of applied
system delivers approximately 0.02 mg of nitroglycerin per hour. Thus,
the 5-, 10-, 15-, 20-, 30-, and 40-cm2 systems deliver approximately
0.1, 0.2, 0.3, 0.4, 0.6, and 0.8 mg of nitroglycerin per hour,
respectively.”
http://www.sch-plough.com/documents/18143666_Nitro-Dur_PI.pdf
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Smoking Cessation (NRT):
Nicorette 10 cm2, 20 cm2, 30 cm2
“Nicorette Patch is available in 5mg/16h (10cm2), 10mg/16h (20cm2) and
15mg/16h (30cm2) patches. Each system contains nicotine at a
concentration of 0.83 mg/cm2.”
http://www.nicorette.com.au/pdf/patchinfo.pdf
Nicotinell: 10 cm2, 20 cm2, 30 cm2
NICOTINELL TTS 10 10 cm²
NICOTINELL TTS 20 20 cm²
NICOTINELL TTS 30 30 cm²
http://home.intekom.com/pharm/novartis/nicotinl.html
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Hypertension:
Catapress-TTS: 3.5 cm2, 7.0 cm2, and 10.5 cm2
“System Structure and Components: Catapres-TTS is a multilayered film,
0.2 mm thick, containing clonidine as the active agent. System area is
3.5, 7.0, or 10.5 cm2 and the amount of drug released is directly
proportional to area. The composition per unit area of all three
dosages is identical.
http://www.rxlist.com/cgi/generic/clonidderm.htm
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Motion Sickness:
Transderm Scop: 2.5 cm2
“The Transderm Scop system is a tan-colored circular patch, 2.5 cm2,
on a clear, oversized, hexagonal peel strip, which is removed prior to
use.”
http://www.rxlist.com/cgi/generic2/transscop_ids.htm
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I hope this information meets your needs.
Best Regards,
Bobbie7-ga |
