A hell of a lot might happen, or nothing might happen. Now, I assume
that your motivation towards asking this question is to find out what
will happen when this sequence is translated to protein. Each amino
acid is coded for by a 3 base sequence of DNA, which is transcribed
into its respective 3 base RNA prior to protein translation. There is
redundancy in the sequences that code for amino acids. Two or more
different 3 base sequences can code for the same amino acid. If your
sequence after the point mutation (changing one base) happens to code
for the same amino acid as the original, there is no functional
change. There are two other possibilities: the most likely is that you
have changed the amino acid that the original was coding for, and this
may have a dramatic effect on the peptide-to-be. Imagine substituting
an alanine for a proline... that could dramatically change your
peptide's properties. Alternatively, you could code for a "stop"
codon, which signals an end to translation. In this case, you chop
your peptide short, and end up with an incomplete protein. I might
also add that a 30 base sequence would only code for a string of 10
amino acids, which isn't much of a protein. Presumably, these 30 bases
are part of a much larger sequence, if they are actually used in
forming a protein. |
