Effects of Drug Interactions with Dexedrine
Stimulant medications such as Dexedrine (dextroamphetamine) should not
be taken with Monoamine Oxidase Inhibitors; serious, even fatal,
interactions can occur. At least 14 days should elapse between
discontinuation of a MAOI and initiation of therapy with citalopram.
Similarly, at least 14 days should be allowed after stopping
citalopram before starting a MAOI. Acidifying agents such as
guanethidine, reserpine, and fruit juices can lower absorption of
Dexedrine. Alkalinizing agents such as Diamox (acetazolamide) increase
absorption of amphetamines. Tricyclic antidepressants may increase
their levels when taken with Dexedrine. Thorazine (chlorpromazine),
lithium, and Haldol (haloperidol)can blunt the effects of Dexedrine
(dextroamphetamine). Dexedrine increases the effects norepinephrine.
Effects of Drug Interactions with Risperdal
Risperdal (risperidone) is a relatively new drug in a line of atypical
antipsychotic drugs or "neuroleptics" that are used to combat both
positive and negative symptoms in schizophrenia. The occurance and
intensity of side effects is reduced in Risperdal, compared to other
drugs that treat psychosis, but serious and permanent side effects can
occur from using Risperdal. "Neuroleptic Malignant Syndrome is a
sometimes fatal reaction to certain psychiatric drugs. The reaction is
characterized by fever, rigid muscles, rapid heartbeat, rapid
breathing, sweating, shaking, seizures, and/or unconsiousness/coma.
The death rate is 20 per cent. Tardive Dyskinesia is a condition that
can cause permanent brain damage. Symptoms of TD include uncontrolled
movements of the mouth, tongue, arms, and legs. The earliest symptom
is usually a "snake-like," fine, involuntary movement of the tongue.
If this is experienced, contact your physician immediately." You
should also check with your physician if you are taking central
nervous system depressants (like antihistamines, hay fever medicines,
sedatives, narcotics, anesthetics, barbiturates, or muscle relaxants)
or if you are taking vasodilators (drug that dilate blood vessels.)
Interaction Between Dexedrine and Risperdal
It would appear you are being treated using an "Augmentation Strategy"
in which the use of drugs not typically thought of as antidepressants
are combined with a standard antidepressant. Such strategies are used
for patients who fail standard therapies or need to quickly speed up
the response of the antidepressant. And according to the German
Journal of Psychiatry's Psychopharmacological Drug Interactions
Calculator ( http://www.gjpsy.uni-goettingen.de/gjpinteraction/interaction_main.php
), there is no known interaction between these two drugs. For your own
interest, you should bookmark this website. It allows a person to
check how prescriptions will react with other prescriptions and
over-the-counter drugs. And it is fairly easy to use. Simply follow
the easy instruction and you will get the results in a matter of
seconds.
You may also want to read over these sites:
RXList:Risperidone – http://www.rxlist.com/cgi/generic/risperid.htm
RXList: Risperidone Drug Interactions –
http://www.rxlist.com/cgi/generic/risperid_ad.htm
RXList: Dextroamphetamine --
http://www.rxlist.com/cgi/generic/dextroamphetamine.htm
RXList: Dextroamphetamine Drug Interactions –
http://www.rxlist.com/cgi/generic/dextroamphetamine_ad.htm
Sources/References
ADHDLivingGuide.com: Medical Treatment – Dexedrine
http://www1.adhdlivingguide.com/mentalhealth/adhd/adhdguide/meds/dex.htm
ADHDLivingGuide.com: Medical Treatment – Risperdal
http://www1.adhdlivingguide.com/mentalhealth/adhd/adhdguide/meds/risperdal_risp.htm
Search Parameters
Google Advanced Search
with all the words: risperidone; dextroamphetamine
with the exact phrase: drug interactions |
